Disregulating processes in the blood system during cancer
Hematologic disturbances in patients with solid malignant tumors, their development mechanism, value, modern pathogenetic principles of correction are considered in the article. The role of cytokines, erythropoietin, blood loss, metastasing of tumors, depressing bone marrow hemopoiesis and increased...
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| Published in: | Bi͡u︡lletenʹ Sibirskoĭ medit͡s︡iny Vol. 5; no. 2; pp. 75 - 83 |
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| Main Authors: | , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Siberian State Medical University (Tomsk)
30-06-2006
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| Subjects: | |
| Online Access: | Get full text |
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| Summary: | Hematologic disturbances in patients with solid malignant tumors, their development mechanism, value, modern pathogenetic principles of correction are considered in the article. The role of cytokines, erythropoietin, blood loss, metastasing of tumors, depressing bone marrow hemopoiesis and increased destroying erythrocytes, microcirculatory disturbances, iron exchange and vitamin B12 in pathogenesis of cancer anemia and also disregulating processes in myeloid hemopoiesis which manifest in the development of neutrophil leucocytosis , eosinophylia and leukemoid reactions in patients having malignant neoplasms is described in details. Hematologic disturbances in malignant growth are frequent manifestations of paraneoplastic syndrome which is a result of system influence of the tumor on the organism. Radial and chemotherapy increase disregulating processes in this vitally important system which require improved methods of their correction. |
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| ISSN: | 1682-0363 1819-3684 |
| DOI: | 10.20538/1682-0363-2006-2-75-83 |