Search Results - "T., Pragna Lakshmi"

Molecular interaction of 2,4-diacetylphloroglucinol (DAPG) with human serum albumin (HSA): The spectroscopic, calorimetric and computational investigation by T., Pragna Lakshmi, Mondal, Moumita, Ramadas, Krishna, Natarajan, Sakthivel

“…Drug molecule interaction with human serum albumin (HSA) affects the distribution and elimination of the drug. The compound, 2,4-diacetylphloroglucinol (DAPG)…”
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A novel homozygous synonymous splicing variant in SELENOI gene causes spastic paraplegia 81 by Sarma, Asodu Sandeep, Siddardha, Bathula, T, Pragna Lakshmi, Ranganath, Prajnya, Dalal, Ashwin

“…Background Hereditary spastic paraplegia 81 is a recently identified, rare autosomal recessive disease, caused by biallelic pathogenic variants in the SELENOI…”
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Short stature and dysmorphic features in Asian Indian siblings with DAAM2‐associated steroid‐resistant nephrotic syndrome: Expansion of the phenotypic spectrum or a blended phenotype? by Pragna Lakshmi, T., Saini, Neelam, Shah, Mehul A., Gowrishankar, Swarnalata, Dalal, Ashwin, Ranganath, Prajnya

“…Variants in more than 60 different genes, most of which code for podocyte‐related proteins, have been found to be associated with monogenic forms of nephrotic…”
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A novel guaiane sesquiterpene derivative, guai-2-en-10α-ol, from Ulva fasciata Delile inhibits EGFR/PI3K/Akt signaling and induces cytotoxicity in triple-negative breast cancer cells by Pragna Lakshmi, T., Vajravijayan, S., Moumita, Mondal, Sakthivel, Natarajan, Gunasekaran, K., Krishna, Ramadas

“…A novel guaiane sesquiterpene derivative, guai-2-en-10α-ol, from Ulva fasciata Delile exhibits antimicrobial property. U. fasciata extract was reported to…”
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Identification of natural allosteric inhibitor for Akt1 protein through computational approaches and in vitro evaluation by Pragna Lakshmi, T., Kumar, Amit, Vijaykumar, Veena, Natarajan, Sakthivel, Krishna, Ramadas

“…•Q7G was identified as natural allosteric inhibitor for Akt1 by performing in silico studies.•It induced apoptosis, decreased p-Akt (Ser473) expression and…”
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The quorum sensing molecule N-acyl homoserine lactone produced by Acinetobacter baumannii displays antibacterial and anticancer properties by John, James, Saranathan, Rajagopalan, Adigopula, Lakshmi Narayana, Thamodharan, Vasanth, Singh, Satya Prakash, Lakshmi, T. Pragna, CharanTej, Mallu Abhiram, Rao, R. Srinivasa, Krishna, R, Rao, H. Surya Prakash, Prashanth, K.

“…Secretory N-acyl homoserine lactones (AHLs) mediate quorum sensing (QS) in bacteria. AHLs are shown to be inhibitory for an unrelated group of bacteria and…”
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Molecular interaction between human serum albumin (HSA) and phloroglucinol derivative that shows selective anti-proliferative potential by Mondal, Moumita, T, Pragna Lakshmi, Krishna, Ramadas, Sakthivel, Natarajan

“…Phloroglucinol and its derivatives possess wide array of biopotentials such as antimicrobial, antioxidant, anti-inflammatory, anticancer and anti-metastatic…”
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A novel guaiane sesquiterpene derivative, guai-2-en-10[alpha]-ol, from Ulva fasciata Delile inhibits EGFR/PI3K/Akt signaling and induces cytotoxicity in triple-negative breast cancer cells by Pragna Lakshmi, T, Vajravijayan, S, Moumita, Mondal, Sakthivel, Natarajan, Gunasekaran, K, Krishna, Ramadas

“…A novel guaiane sesquiterpene derivative, guai-2-en-10[alpha]-ol, from Ulva fasciata Delile exhibits antimicrobial property. U. fasciata extract was reported…”
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