Search Results - "T M de Rosales, Rafael"

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    Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging by Gawne, Peter J., Man, Francis, Blower, Philip J., T. M. de Rosales, Rafael

    Published in Chemical reviews (08-06-2022)
    “…The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical application in a rational manner depends on reliable, clinically…”
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    Journal Article
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    Imaging Nanomedicine-Based Drug Delivery: a Review of Clinical Studies by Man, Francis, Lammers, Twan, T. M. de Rosales, Rafael

    Published in Molecular imaging and biology (01-10-2018)
    “…Imaging plays a key role in the preclinical evaluation of nanomedicine-based drug delivery systems and it has provided important insights into their mechanism…”
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    Journal Article
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    Harnessing Nanomedicine to Potentiate the Chemo-Immunotherapeutic Effects of Doxorubicin and Alendronate Co-Encapsulated in Pegylated Liposomes by Gabizon, Alberto, Shmeeda, Hilary, Draper, Benjamin, Parente-Pereira, Ana, Maher, John, Carrascal-Miniño, Amaia, de Rosales, Rafael T. M, La-Beck, Ninh M

    Published in Pharmaceutics (01-11-2023)
    “…Encapsulation of Doxorubicin (Dox), a potent cytotoxic agent and immunogenic cell death inducer, in pegylated (Stealth) liposomes, is well known to have major…”
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    Fucoidan Prolongs the Circulation Time of Dextran-Coated Iron Oxide Nanoparticles by Abdollah, Maha R. A, Carter, Thomas J, Jones, Clare, Kalber, Tammy L, Rajkumar, Vineeth, Tolner, Berend, Gruettner, Cordula, Zaw-Thin, May, Baguña Torres, Julia, Ellis, Matthew, Robson, Mathew, Pedley, R. Barbara, Mulholland, Paul, T. M. de Rosales, Rafael, Chester, Kerry Ann

    Published in ACS nano (27-02-2018)
    “…The magnetic properties and safety of dextran-coated superparamagnetic iron oxide nanoparticles (SPIONs) have facilitated their clinical use as MRI contrast…”
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    Rapid short-pulses of focused ultrasound and microbubbles deliver a range of agent sizes to the brain by Lim Kee Chang, William, Chan, Tiffany G., Raguseo, Federica, Mishra, Aishwarya, Chattenton, Dani, de Rosales, Rafael T. M., Long, Nicholas J., Morse, Sophie V.

    Published in Scientific reports (28-04-2023)
    “…Focused ultrasound and microbubbles can non-invasively and locally deliver therapeutics and imaging agents across the blood–brain barrier. Uniform treatment…”
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    Microwave-assisted synthesis of [52Mn]Mn-porphyrins: Applications in cell and liposome radiolabelling by Gawne, Peter J., Pinto, Sara M.A., Nielsen, Karin M., Keeling, George P., Pereira, Mariette M., T. M. de Rosales, Rafael

    Published in Nuclear medicine and biology (01-11-2022)
    “…Manganese porphyrins have several therapeutic/imaging applications, including their use as radioprotectants (in clinical trials) and as paramagnetic MRI…”
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    Liposome delivery to the brain with rapid short-pulses of focused ultrasound and microbubbles by Morse, Sophie V., Mishra, Aishwarya, Chan, Tiffany G., T. M. de Rosales, Rafael, Choi, James J.

    Published in Journal of controlled release (01-01-2022)
    “…Liposomes are clinically used drug carriers designed to improve the delivery of drugs to specific tissues while minimising systemic distribution. However,…”
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    NHS-Functionalized THP Derivative for Efficient Synthesis of Kit-Based Precursors for 68Ga Labeled PET Probes by Floresta, Giuseppe, Keeling, George P., Memdouh, Siham, Meszaros, Levente K., de Rosales, Rafael T. M., Abbate, Vincenzo

    Published in Biomedicines (01-04-2021)
    “…Hexadentate tris(3,4-hydroxypyridinone) ligands (THP) complex Fe3+ at very low iron concentrations and their high affinities for oxophilic trivalent metal ions…”
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    68Ga-bisphosphonates for the imaging of extraosseous calcification by positron emission tomography by Keeling, George P., Baark, Friedrich, Katsamenis, Orestis L., Xue, Jing, Blower, Philip J., Bertazzo, Sergio, T. M. de Rosales, Rafael

    Published in Scientific reports (05-09-2023)
    “…Radiolabelled bisphosphonates (BPs) and [ 18 F]NaF ( 18 F-fluoride) are the two types of radiotracers available to image calcium mineral (e.g. bone), yet only…”
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    PET Imaging of Small Extracellular Vesicles via [89Zr]Zr(oxinate)4 Direct Radiolabeling by Khan, Azalea A, Man, Francis, Faruqu, Farid N, Kim, Jana, Al-Salemee, Fahad, Carrascal-Miniño, Amaia, Volpe, Alessia, Liam-Or, Revadee, Simpson, Paul, Fruhwirth, Gilbert O, Al-Jamal, Khuloud T, T. M. de Rosales, Rafael

    Published in Bioconjugate chemistry (16-03-2022)
    “…Exosomes or small extracellular vesicles (sEVs) are increasingly gaining attention for their potential as drug delivery systems and biomarkers of disease…”
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    On the Versatility of Nanozeolite Linde Type L for Biomedical Applications: Zirconium-89 Radiolabeling and In Vivo Positron Emission Tomography Study by Lacerda, Sara, Zhang, Wuyuan, T. M. de Rosales, Rafael, Da Silva, Isidro, Sobilo, Julien, Lerondel, Stéphanie, Tóth, Éva, Djanashvili, Kristina

    Published in ACS applied materials & interfaces (27-07-2022)
    “…Porous materials, such as zeolites, have great potential for biomedical applications, thanks to their ability to accommodate positively charged metal-ions and…”
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    [68Ga]Ga-THP-Pam: A Bisphosphonate PET Tracer with Facile Radiolabeling and Broad Calcium Mineral Affinity by Keeling, George P, Sherin, Billie, Kim, Jana, San Juan, Belinda, Grus, Tilmann, Eykyn, Thomas R, Rösch, Frank, Smith, Gareth E, Blower, Philip J, Terry, Samantha Y. A, T. M. de Rosales, Rafael

    Published in Bioconjugate chemistry (21-07-2021)
    “…Calcium minerals such as hydroxyapatite (HAp) can be detected noninvasively in vivo using nuclear imaging agents such as [18F]­NaF (available from cyclotrons),…”
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    [Ga]Ga-THP-tetrazine for bioorthogonal click radiolabelling: pretargeted PET imaging of liposomal nanomedicines by Mishra, Aishwarya, Carrascal-Miniño, Amaia, Kim, Jana, de Rosales, Rafael

    Published in RSC chemical biology (03-07-2024)
    “…Pretargeted PET imaging using bioorthogonal chemistry is a leading strategy for the tracking of long-circulating agents such as antibodies and…”
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