Search Results - "T Khayyal, Mohamed"

Antidiabetic Effects of a Standardized Egyptian Rice Bran Extract by Kaup, Rebecca M., Khayyal, Mohamed T., Verspohl, Eugen J.

“…An extract was prepared from Egyptian stabilized rice bran and standardized to contain 2% γ‐oryzanol in addition to its content of other bioactives, notably…”
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GPR84 and TREM-1 Signaling Contribute to the Pathogenesis of Reflux Esophagitis by Abdel-Aziz, Heba, Schneider, Mathias, Neuhuber, Winfried, Meguid Kassem, Abdel, Khailah, Saleem, Müller, Jürgen, Gamal Eldeen, Hadeel, Khairy, Ahmed, T Khayyal, Mohamed, Shcherbakova, Anastasiia, Efferth, Thomas, Ulrich-Merzenich, Gudrun

“…Gastro-esophageal reflux disease (GERD) is one of the most common disorders in gastroenterology. Patients present with or without increased acid exposure…”
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Effect of the standard herbal preparation, STW5, treatment on dysbiosis induced by dextran sodium sulfate in experimental colitis by Mohamed, Sarah S, Abdeltawab, Nourtan F, Wadie, Walaa, Ahmed, Lamiaa A, Ammar, Ramy M, Rabini, Sabine, Abdel-Aziz, Heba, Khayyal, Mohamed T

“…The standardized herbal preparation, STW 5, is effective clinically in functional gastrointestinal disorders and experimentally in ulcerative colitis (UC). The…”
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Intestinal injury can be effectively prevented by Dunaliella salina in gamma irradiated rats by Khayyal, Mohamed T., El-Baz, Farouk K., Meselhy, Meselhy R., Ali, Gamila H., El-Hazek, Rania M.

“…Dunaliella salina (D. salina) is one of the most common microalgae that is used as human food. It is isolated from the salty lakes in El-Fayoum and Lake of…”
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Effect of an Herbal Preparation, STW 5, in an Acute Model of Reflux Oesophagitis in Rats by Abdel-Aziz, Heba, Zaki, Hala F., Neuhuber, Winfried, Kelber, Olaf, Weiser, Dieter, Khayyal, Mohamed T.

“…A multitarget herbal preparation, STW 5, has been used clinically in different gastrointestinal disorders including functional dyspepsia and irritable bowel…”
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Niacin modulates depressive-like behavior in experimental colitis through GPR109A-dependent mechanisms by Wadie, Walaa, Mohamed, Sarah S., Abd El-Haleim, Enas A., Khayyal, Mohamed T.

“…Depression is one of the common neurological comorbidities in patients with inflammatory bowel disease (IBD). The current study aimed to investigate the…”
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Effect of methimazole treatment on doxorubicin-induced cardiotoxicity in mice by Osman, Abdel-Moneim M., Nemnem, Marwa M., Abou-Bakr, Amany A., Nassier, Omimah A., Khayyal, Mohamed T.

“…The major limiting factor in long-term administration of doxorubicin is the development of cumulative dose-dependent cardiomyopathy and congestive heart…”
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Rice bran extract mitigates depressive-like behavior in dextran sulfate sodium-induced colitis: Involvement of the gut-brain axis and Sirt1 signaling pathway by Shendy, Hagar M., Mohamed, Sarah S., Abd El-Haleim, Enas A., Galal, Omneya, Wadie, Walaa, Helal, Amr, Khayyal, Mohamed T.

“…Inflammatory bowel disease (IBD) patients frequently suffer from depressive disorders as well. The present study was carried out to explore whether treatment…”
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Corrigendum to “Rice bran extract mitigates depressive-like behavior in dextran sulfate sodium-induced colitis: Involvement of the gut-brain axis and Sirt1 signaling pathway” [Food and Chemical Toxicology 184 (2024) 114386] by Shendy, Hagar M., Mohamed, Sarah S., Abd El-Haleim, Enas A., Galal, Omneya, Wadie, Walaa, Helal, Amr, Khayyal, Mohamed T.

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Naphthoquinone derivatives as P-glycoprotein inducers in inflammatory bowel disease: 2D monolayers, 3D spheroids, and in vivo models by Mahmoud, Nuha, Hegazy, Mohamed-Elamir F., Wadie, Walaa, Elbadawi, Mohamed, Fleischer, Edmond, Klinger, Anette, Bringmann, Gerhard, Khayyal, Mohamed T., Efferth, Thomas

“…Inflammatory bowel disease (IBD) represents a chronic inflammation of the gastrointestinal tract characterized by an overreaction of immune responses and…”
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Micellar solubilisation enhances the antiinflammatory activities of curcumin and boswellic acids in rats with adjuvant-induced arthritis by Khayyal, Mohamed T., El-Hazek, Rania M., El-Sabbagh, Walaa A., Frank, Jan, Behnam, Dariush, Abdel-Tawab, Mona

“…•Micellar curcumin is much more active than the native extract in inhibiting paw edema induced by adjuvant inoculation.•Reduction in paw volume is associated…”
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Micellar solubilization enhances the anti-inflammatory effect of xanthohumol by Khayyal, Mohamed T., El-Hazek, Rania M., El-Sabbagh, Walaa A., Frank, Jan, Behnam, Dariush, Abdel-Tawab, Mona

“…•Micellization of xanthohumol enhances its anti-inflammatory activity in adjuvant-induced arthritis.•Micellar xanthohumol was more potent than the native form…”
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Propolis extract protects against radiation-induced intestinal mucositis through anti-apoptotic mechanisms by Khayyal, Mohamed T., Abdel-Naby, Doaa H., El-Ghazaly, Mona A.

“…Intestinal mucositis is a common side effect during radiotherapy that could be largely prevented by compounds possessing anti-inflammatory or anti-oxidant…”
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Rice bran extract compensates mitochondrial dysfunction in a cellular model of early Alzheimer's disease by Hagl, Stephanie, Grewal, Rekha, Ciobanu, Ion, Helal, Amr, Khayyal, Mohamed T, Muller, Walter E, Eckert, Gunter P

“…Mitochondrial dysfunction plays an important role in brain aging and has emerged to be an early event in Alzheimer's disease (AD), contributing to…”
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Bacteria-Derived Compatible Solutes Ectoine and 5α-Hydroxyectoine Act as Intestinal Barrier Stabilizers to Ameliorate Experimental Inflammatory Bowel Disease by Abdel-Aziz, Heba, Wadie, Walaa, Scherner, Olaf, Efferth, Thomas, Khayyal, Mohamed T

“…Earlier studies showed that the compatible solute ectoine (1) given prophylactically before induction of colitis by 2,4,6-trinitrobenzenesulfonic acid (TNBS)…”
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Comparative Pharmacokinetic Study of Standard Astaxanthin and its Micellar Formulation in Healthy Male Volunteers by Khayyal, Mohamed T., Teaima, Mahmoud H., Marzouk, Hoda M., -Hazek, Rania M. El, Behnam, Frank, Behnam, Dariush

“…Background and Objective Astaxanthin is a naturally occurring carotenoid with high anti-oxidant properties, but it is a very lipophilic compound with low oral…”
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Novel effects of ectoine, a bacteria-derived natural tetrahydropyrimidine, in experimental colitis by Abdel-Aziz, Heba, Wadie, Walaa, Abdallah, Dalaal M., Lentzen, Georg, Khayyal, Mohamed T.

“…Evidence suggests an important role of intestinal barrier dysfunction in the etiology of inflammatory bowel disease (IBD). Therefore stabilizing mucosal…”
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Effect of the Herbal Preparation, STW 5, on the Microbiome in an Experimental Model of Functional Dyspepsia by Khayyal, Mohamed T, Abdeltawab, Nourtan F, El-Sayed, Sarah, Vinson, Bettina, Abdel-Aziz, Heba

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The herbal preparation STW 5 affects serotonergic pathways in the brain and colon as well as stress parameters in experimental irritable bowel syndrome by gamal, Nehal G., Abd El‐Salam, Rania M., Gadelrub, Laila N., Ahmed‐Farid, Omar A., Khayyal, Mohamed T.

“…Background Exposure to stress has been related to disturbance in 5‐hydroxytryptamine (5‐HT) signaling in the brain‐gut axis and is considered as a major…”
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Effect of a chamomile extract in protecting against radiation‐induced intestinal mucositis by Khayyal, Mohamed T., Kreuter, Matthias Heinrich, Kemmler, Michael, Altmann, Peter, Abdel‐Naby, Doaa H., El‐Ghazaly, Mona A.

“…Compounds that prevent radiation‐induced mucositis may offer new therapeutic strategies for maintaining intestinal integrity in patients undergoing…”
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