Search Results - "Tőzsér, József"

Changes in the Chemical Barrier Composition of Tears in Alzheimer's Disease Reveal Potential Tear Diagnostic Biomarkers by Kalló, Gergő, Emri, Miklós, Varga, Zsófia, Ujhelyi, Bernadett, Tőzsér, József, Csutak, Adrienne, Csősz, Éva

“…Alzheimer's disease (AD) is one of the most common neurodegenerative diseases, with increasing prevalence affecting millions of people worldwide. Currently,…”
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Aloe vera downregulates LPS-induced inflammatory cytokine production and expression of NLRP3 inflammasome in human macrophages by Budai, Marietta M., Varga, Aliz, Milesz, Sándor, Tőzsér, József, Benkő, Szilvia

“…•Aloe vera reduces inflammatory cytokine production in LPS-treated human macrophages.•Aloe vera inhibits the expression of IL-1beta and Nlrp3 inflammasome…”
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Analysis of the efficacy of HIV protease inhibitors against SARS-CoV-2′s main protease by Mahdi, Mohamed, Mótyán, János András, Szojka, Zsófia Ilona, Golda, Mária, Miczi, Márió, Tőzsér, József

“…Abstract Background The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in millions of infections worldwide. While…”
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Proteomics investigation of OSCC-specific salivary biomarkers in a Hungarian population highlights the importance of identification of population-tailored biomarkers by Csősz, Éva, Lábiscsák, Péter, Kalló, Gergő, Márkus, Bernadett, Emri, Miklós, Szabó, Adrienn, Tar, Ildikó, Tőzsér, József, Kiss, Csongor, Márton, Ildikó

“…Oral squamous cell carcinoma (OSCC) accounting for about 90% of malignant oral lesions is the 6th most common malignancy worldwide. Diagnostic delay may…”
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Biochemical characterization of Ty1 retrotransposon protease by Gazda, Lívia Diána, Joóné Matúz, Krisztina, Nagy, Tibor, Mótyán, János András, Tőzsér, József

“…Ty1 is one of the many transposons in the budding yeast Saccharomyces cerevisiae. The life-cycle of Ty1 shows numerous similarities with that of retroviruses,…”
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Research applications of proteolytic enzymes in molecular biology by Mótyan, Janos Andras, Tóth, Ferenc, Tozser, József

“…Proteolytic enzymes (also termed peptidases, proteases and proteinases) are capable of hydrolyzing peptide bonds in proteins. They can be found in all living…”
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Effect of inducible bone morphogenetic protein 2 expression on the osteogenic differentiation of dental pulp stem cells in vitro by Tóth, Ferenc, Gáll, József M., Tőzsér, József, Hegedűs, Csaba

“…Bone morphogenetic protein 2 (BMP-2) is a member of the transforming growth factor-β superfamily, it is known to be a factor involved in skeletal development…”
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Quantitative analysis of proteins in the tear fluid of patients with diabetic retinopathy by Csősz, Éva, Boross, Péter, Csutak, Adrienne, Berta, András, Tóth, Ferenc, Póliska, Szilárd, Török, Zsolt, Tőzsér, József

“…Diabetic retinopathy is the leading cause of new cases of legal blindness among adults in the developed countries. Approximately 40% of all people with…”
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Analysis of networks of host proteins in the early time points following HIV transduction by Csősz, Éva, Tóth, Ferenc, Mahdi, Mohamed, Tsaprailis, George, Emri, Miklós, Tőzsér, József

“…Utilization of quantitative proteomics data on the network level is still a challenge in proteomics data analysis. Currently existing models use sophisticated,…”
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Identification of Host Cellular Protein Substrates of SARS-COV-2 Main Protease by Miczi, Márió, Golda, Mária, Kunkli, Balázs, Nagy, Tibor, Tőzsér, József, Mótyán, János András

“…The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease-19 (COVID-19) being associated with severe…”
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Plasminogen activator activity in tears of pregnant women by Csutak, Adrienne, Steiber, Zita, Tőzsér, József, Jakab, Attila, Berta, András, Silver, David M

“…Plasminogen activator activity (PAA) in tears of pregnant women was investigated at various gestation times to assess the availability of plasminogen activator…”
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Efficacy of Integrase Strand Transfer Inhibitors and the Capsid Inhibitor Lenacapavir against HIV-2, and Exploring the Effect of Raltegravir on the Activity of SARS-CoV-2 by Kiarie, Irene Wanjiru, Hoffka, Gyula, Laporte, Manon, Leyssen, Pieter, Neyts, Johan, Tőzsér, József, Mahdi, Mohamed

“…Retroviruses perpetuate their survival by incorporating a copy of their genome into the host cell, a critical step catalyzed by the virally encoded integrase…”
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Compounds with Antiviral, Anti-Inflammatory and Anticancer Activity Identified in Wine from Hungary's Tokaj Region via High Resolution Mass Spectrometry and Bioinformatics Analyses by Kalló, Gergő, Kunkli, Balázs, Győri, Zoltán, Szilvássy, Zoltán, Csősz, Éva, Tőzsér, József

“…(1) Background: Wine contains a variety of molecules with potential beneficial effects on human health. Our aim was to examine the wine components with…”
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Wound-Healing Markers Revealed by Proximity Extension Assay in Tears of Patients following Glaucoma Surgery by Csősz, Éva, Tóth, Noémi, Deák, Eszter, Csutak, Adrienne, Tőzsér, József

“…Tears are a constantly available and highly valuable body fluid collectable by non-invasive techniques. Although it can give information on ocular status and…”
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Comparative Analysis of Differential Cellular Transcriptome and Proteome Regulation by HIV-1 and HIV-2 Pseudovirions in the Early Phase of Infection by Linkner, Tamás Richárd, Ambrus, Viktor, Kunkli, Balázs, Szojka, Zsófia Ilona, Kalló, Gergő, Csősz, Éva, Kumar, Ajneesh, Emri, Miklós, Tőzsér, József, Mahdi, Mohamed

“…In spite of the similar structural and genomic organization of human immunodeficiency viruses type 1 and 2 (HIV-1 and HIV-2), striking differences exist…”
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P1′ specificity of the S219V/R203G mutant tobacco etch virus protease by Golda, Mária, Hoffka, Gyula, Cherry, Scott, Tropea, Joseph E., Lountos, George T., Waugh, David S., Wlodawer, Alexander, Tőzsér, József, Mótyán, János András

“…Proteases that recognize linear amino acid sequences with high specificity became indispensable tools of recombinant protein technology for the removal of…”
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Specificity Studies of the Venezuelan Equine Encephalitis Virus Non-Structural Protein 2 Protease Using Recombinant Fluorescent Substrates by Bozóki, Beáta, Mótyán, János András, Hoffka, Gyula, Waugh, David S, Tőzsér, József

“…The non-structural protein 2 (nsP2) of alphavirus Venezuelan equine encephalitis virus (VEEV) is a cysteine protease that is responsible for processing of the…”
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Alternatively spliced exon regulates context-dependent MEF2D higher-order assembly during myogenesis by Gönczi, Mónika, Teixeira, João M. C., Barrera-Vilarmau, Susana, Mediani, Laura, Antoniani, Francesco, Nagy, Tamás Milán, Fehér, Krisztina, Ráduly, Zsolt, Ambrus, Viktor, Tőzsér, József, Barta, Endre, Kövér, Katalin E., Csernoch, László, Carra, Serena, Fuxreiter, Monika

“…During muscle cell differentiation, the alternatively spliced, acidic β-domain potentiates transcription of Myocyte-specific Enhancer Factor 2 (Mef2D)…”
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Metabolomic Analysis of Serum and Tear Samples from Patients with Obesity and Type 2 Diabetes Mellitus by Nokhoijav, Erdenetsetseg, Guba, Andrea, Kumar, Ajneesh, Kunkli, Balázs, Kalló, Gergő, Káplár, Miklós, Somodi, Sándor, Garai, Ildikó, Csutak, Adrienne, Tóth, Noémi, Emri, Miklós, Tőzsér, József, Csősz, Éva

“…Metabolomics strategies are widely used to examine obesity and type 2 diabetes (T2D). Patients with obesity ( = 31) or T2D ( = 26) and sex- and age-matched…”
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Identification of SARS-CoV-2 Main Protease (Mpro) Cleavage Sites Using Two-Dimensional Electrophoresis and In Silico Cleavage Site Prediction by Miltner, Noémi, Kalló, Gergő, Csősz, Éva, Miczi, Márió, Nagy, Tibor, Mahdi, Mohamed, Mótyán, János András, Tőzsér, József

“…The main protease (Mpro) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays a crucial role in its life cycle. The Mpro-mediated limited…”
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