Search Results - "Türkay, Metin"

Multiobjective Optimization of Mixed-Integer Linear Programming Problems: A Multiparametric Optimization Approach by Pappas, Iosif, Avraamidou, Styliani, Katz, Justin, Burnak, Baris, Beykal, Burcu, Türkay, Metin, Pistikopoulos, Efstratios N

“…Industrial process systems need to be optimized, simultaneously satisfying financial, quality, and safety criteria. To meet all of those potentially…”
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A CLOCK-binding small molecule disrupts the interaction between CLOCK and BMAL1 and enhances circadian rhythm amplitude by Doruk, Yagmur Umay, Yarparvar, Darya, Akyel, Yasemin Kubra, Gul, Seref, Taskin, Ali Cihan, Yilmaz, Fatma, Baris, Ibrahim, Ozturk, Nuri, Türkay, Metin, Ozturk, Narin, Okyar, Alper, Kavakli, Ibrahim Halil

“…Proper function of many physiological processes requires a robust circadian clock. Disruptions of the circadian clock can result in metabolic diseases, mood…”
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31st European Symposium on Computer Aided Process Engineering: Escape-31 by Türkay, Metin, Gani, Rafiqul

“…The 31st European Symposium on Computer Aided Process Engineering: ESCAPE-31, Volume 50 contains the papers presented at the 31st European Symposium of…”
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Structure based discovery of small molecules to regulate the activity of human insulin degrading enzyme by Çakir, Bilal, Dağliyan, Onur, Dağyildiz, Ezgi, Bariş, İbrahim, Kavakli, Ibrahim Halil, Kizilel, Seda, Türkay, Metin

“…Insulin-degrading enzyme (IDE) is an allosteric Zn(+2) metalloprotease involved in the degradation of many peptides including amyloid-β, and insulin that play…”
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Optimal estimation of physical properties of the products of an atmospheric distillation column using support vector regression by Serfidan, Ahmet Can, Uzman, Firat, Türkay, Metin

“…Atmospheric distillation column is one of the most important units in an oil refinery where crude oil is fractioned into its more valuable constituents. Almost…”
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Optimal locations of electric public charging stations using real world vehicle travel patterns by Shahraki, Narges, Cai, Hua, Turkay, Metin, Xu, Ming

“…•Formulating an optimization model for selecting public charging stations.•Maximizing electrified vehicle-miles-traveled for potential environmental…”
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Sustainability in Supply Chain Management: Aggregate Planning from Sustainability Perspective by Türkay, Metin, Saraçoğlu, Öztürk, Arslan, Mehmet Can

“…Supply chain management that considers the flow of raw materials, products and information has become a focal issue in modern manufacturing and service…”
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A bi-criteria optimization model to analyze the impacts of electric vehicles on costs and emissions by Kabatepe, Bora, Türkay, Metin

“…•Impact assesment of electric vehicles.•A bi-criteria optimization model is constructed for electricity dispatching needs for charging electric…”
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SASS: slicing with adaptive steps search method for finding the non-dominated points of tri-objective mixed-integer linear programming problems by Rasmi, Seyyed Amir Babak, Fattahi, Ali, Türkay, Metin

“…Multi-objective optimization problems (MOOP) reflect the complexity of many real-world decision problems where objectives are conflicting. The presence of more…”
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Structure-based design and classifications of small molecules regulating the circadian rhythm period by Gul, Seref, Rahim, Fatih, Isin, Safak, Yilmaz, Fatma, Ozturk, Nuri, Turkay, Metin, Kavakli, Ibrahim Halil

“…Circadian rhythm is an important mechanism that controls behavior and biochemical events based on 24 h rhythmicity. Ample evidence indicates disturbance of…”
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Optimizing product assortment under customer-driven demand substitution by Yücel, Eda, Karaesmen, Fikri, Salman, F. Sibel, Türkay, Metin

“…The problem of product assortment and inventory planning under customer-driven demand substitution is analyzed and a mathematical model for this problem is…”
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Discovery of a small molecule that selectively destabilizes Cryptochrome 1 and enhances life span in p53 knockout mice by Gul, Seref, Akyel, Yasemin Kubra, Gul, Zeynep Melis, Isin, Safak, Ozcan, Onur, Korkmaz, Tuba, Selvi, Saba, Danis, Ibrahim, Ipek, Ozgecan Savlug, Aygenli, Fatih, Taskin, Ali Cihan, Akarlar, Büşra Aytül, Ozlu, Nurhan, Ozturk, Nuri, Ozturk, Narin, Ünal, Durişehvar Özer, Guzel, Mustafa, Turkay, Metin, Okyar, Alper, Kavakli, Ibrahim Halil

“…Cryptochromes are negative transcriptional regulators of the circadian clock in mammals. It is not clear how reducing the level of endogenous CRY1 in mammals…”
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GoNDEF: an exact method to generate all non-dominated points of multi-objective mixed-integer linear programs by Rasmi, Seyyed Amir Babak, Türkay, Metin

“…Most real-world problems involve multiple conflicting criteria. These problems are called multi-criteria/multi-objective optimization problems (MOOP). The main…”
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Bicriteria optimization approach to analyze incorporation of biofuel and carbon capture technologies by Ozturk, Ali, Turkay, Metin

“…Environmental considerations has become a central issue in the process industries. The energy sector attracts the majority of attention, since it is…”
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Optimization based tumor classification from microarray gene expression data by Dagliyan, Onur, Uney-Yuksektepe, Fadime, Kavakli, I Halil, Turkay, Metin

“…An important use of data obtained from microarray measurements is the classification of tumor types with respect to genes that are either up or down regulated…”
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A multi-criteria decision analysis to include environmental, social, and cultural issues in the sustainable aggregate production plans by Rasmi, Seyyed Amir Babak, Kazan, Cem, Türkay, Metin

“…•A quad-objective MILP (QOMILP) aggregate planning problems is developed.•A solution method for finding the non-dominated points (ND) of QOMILPs is…”
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Disjunctive Programming Techniques for the Optimization of Process Systems with Discontinuous Investment Costs−Multiple Size Regions by Türkay, Metin, Grossmann, Ignacio E

“…This paper addresses the optimization of process models that involve discontinuous investment cost functions with fixed charges and are defined over several…”
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A mixed-integer programming approach to multi-class data classification problem by Turkay, Metin, Uney, Fadime

“…This paper presents a new data classification method based on mixed-integer programming. Traditional approaches that are based on partitioning the data sets…”
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Optimization of Operations in Supply Chain Systems Using Hybrid Systems Approach and Model Predictive Control by Mestan, Esen, Türkay, Metin, Arkun, Yaman

“…This paper addresses the optimal operation of multiproduct supply chain systems, using Model Predictive Control (MPC). The supply chain considered in this…”
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A mixed-integer programming approach to the clustering problem with an application in customer segmentation by Sağlam, Burcu, Salman, F. Sibel, Sayın, Serpil, Türkay, Metin

“…This paper presents a mathematical programming based clustering approach that is applied to a digital platform company’s customer segmentation problem…”
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