Search Results - "Tökes, Z A"

Matrix metalloproteinases in the neocortex and spinal cord of amyotrophic lateral sclerosis patients by Lim, G P, Backstrom, J R, Cullen, M J, Miller, C A, Atkinson, R D, Tökés, Z A

“…Matrix metalloproteinases (MMPs) were analyzed by immunohistochemistry and zymography in amyotrophic lateral sclerosis (ALS) and control brain and spinal cord…”
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The 84-kDa form of human matrix metalloproteinase-9 degrades substance P and gelatin by Backstrom, J R, Tökés, Z A

“…Matrix metalloproteinase-9 (MMP-9) is secreted from cells and, once activated, is thought to degrade collagen in the extracellular matrix. Because collagen is…”
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Characterization of neutral proteinases from Alzheimer-affected and control brain specimens: identification of calcium-dependent metalloproteinases from the hippocampus by Backstrom, J R, Miller, C A, Tökés, Z A

“…Three neutral proteinases from human hippocampal tissue have been identified and partially characterized using substrate gel electrophoresis. The proteinases…”
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Proteolytic activity associated with the nuclear scaffold. The effect of self-digestion on lamins by TOKES, Z. A, CLAWSON, G. A

“…The inner aspect of the nuclear envelope is supported by a peripheral framework called the nuclear scaffold, which consists of both structural and functional…”
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Matrix Metalloproteinase-9 (MMP-9) Is Synthesized in Neurons of the Human Hippocampus and Is Capable of Degrading the Amyloid-beta Peptide (1-40) by Backstrom, Jon R, Lim, Giselle P, Cullen, Michael J, Tokes, Zoltan A

“…We reported earlier that the levels of Ca2+-dependent metalloproteinases are increased in Alzheimer's disease (AD) specimens, relative to control specimens…”
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Matrix Metalloproteinases in Dog Brains Exhibiting Alzheimer‐Like Characteristics by Lim, Giselle P., Russell, Michael J., Cullen, Michael J., Tökés, Zoltán A.

“…: We have previously reported that the amount of the neuronal matrix metalloproteinase (MMP) MMP‐9, capable of cleaving β‐amyloid1–40 predominantly at…”
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Use of Anionic Liposomes for the Reduction of Chronic Doxorubicin-Induced Cardiotoxicity by Forssen, Eric A., Tokes, Zoltan A.

“…Anionic liposomes containing doxorubicin were evaluated in mice for therapeutic potential in reducing the risks of chronic cardiotoxicity characteristic of…”
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Synthesis of Adriamycin-Coupled Polyglutaraldehyde Microspheres and Evaluation of Their Cytostatic Activity by Tokes, Zoltan A., Rogers, Kathryn E., Rembaum, Alan

“…Adriamycin was coupled to polyglutaraldehyde microspheres having an average diameter of 4500 angstrom. The coupled microspheres remained stable during…”
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Induction of erythroid differentiation in human leukemic K-562 cells by membrane-directed action of adriamycin covalently bound to microspheres by JEANNESSON, P, TRENTESAUX, C, GERARD, B, JARDILLIER, J.-C, ROSS, K. L, TOKES, Z. A

“…Covalent coupling of Adriamycin (ADR) to polyglutaraldehyde microspheres focuses the drug action to the plasma membrane which leads to growth inhibition and…”
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Synthesis, biological evaluation, and quantitative structure-activity relationship analysis of 2-hydroxy-1H-isoindolediones as new cytostatic agents by Chan, Carcy L, Lien, Eric J, Tokes, Zoltan A

“…A series of 16 derivatives of 2-hydroxy-1H-isoindole-1,3-diones was designed and synthesized as potential antitumor agents. The cytostatic activity against…”
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The 46-kDa nucleoside triphosphatase of rat liver nuclear scaffold represents the N-terminal portion of lamins A/C by Clawson, G A, Lackey, A, Tokes, Z A

“…The major nucleoside triphosphatase (NTPase) of rat liver nuclear scaffold (NS) or envelope, which is thought to participate in nucleocytoplasmic transport,…”
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Phenotypic variations dictate the intracellular compartmentalization of doxorubicin in normal human bone marrow cells by AGHAÏ, E, TOKES, Z. A

“…In vitro accumulation of doxorubicin in intracellular compartments of normal bone marrow cells was studied with the use of fluorescent microscopy. Both the…”
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Creatine kinase BB: a new tumor-associated marker by Silverman, L M, Dermer, G B, Zweig, M H, Van Steirteghem, A C, Tökés, Z A

“…Creatine kinase isoenzyme BB (CK-BB) is found in the serum of patients with various types of cancer. Using both radioimmunoassay and agarose electrophoresis,…”
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Immunoperoxidase localization of a glycoprotein on plasma membrane of secretory epithelium from human breast by Imam, A, Tokes, ZA

“…A glycoprotein component of human milk-fat globule membrane, which is said to derive form apical plasma membrane of mammary secretory epithelium, has been…”
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Immunohistochemical study of the expression of human milk fat globule membrane glycoprotein 70 by ASHRAF IMAM, TAYLOR, C. R, TOKES, Z. A

“…Human milk fat globule membrane, which is said to derive from apical plasma membrane of secretory epithelial cells in breast, was analyzed by sodium dodecyl…”
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Immunohistochemical localization of keratin in human prostate by Kitajima, K, Tökés, Z A

“…The localization of keratin was investigated in normal human prostate, benign prostatic hyperplasia (BPH), and prostatic adenocarcinoma using…”
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Preferential expression of a Mr 155,000 milk-fat-globule membrane glycoprotein on luminal epithelium of lobules in human breast by IMAM, A, DRUSHELLA, M. M, TAYLOR, C. R, TOKES, Z. A

“…An integral membrane glycoprotein with an apparent molecular weight of 155,000 and isoelectric points ranging from 7.2 to 7.6 has been found to be…”
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Active proteinase inhibitors associated with human breast epithelial cells by Gendler, S J, Tökés, Z A

“…The major glycoproteins synthesized by human breast epithelial cells have been characterized [6,8]. The most consistently observed and prominent component in…”
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Neurotoxicity and dermatotoxicity of cyanomorpholinyl adriamycin by CRAMER, S. C, RHODES, R. H, ACTON, E. M, TOKES, Z. A

“…The highly lipophilic cyanomorpholinyl adriamycin (CMA) is the most potent antineoplastic anthracycline yet described. CNS distribution and toxicity were…”
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Inhibition of tumor cell growth by Schiff bases of hydroxysemicarbazide by Ren, S, Tokes, Z A, Csipke, C, Zhou, B, Yen, Y, Lien, E J

“…The inhibitory activities of Schiff bases of hydroxysemicarbazide (HSC) against eight human and murine tumor cell lines and one non-cancer cell line were…”
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