Search Results - "Tóth, Ádám V."

Reviewing critical TRPM2 variants through a structure-function lens by Tóth, Ádám V., Bartók, Ádám

“…The transient receptor potential melastatin 2 (TRPM2) channel plays a central role in connecting redox state with calcium signaling in living cells. This…”
Get full text

High-throughput ligand profile characterization in novel cell lines expressing seven heterologous insect olfactory receptors for the detection of volatile plant biomarkers by Zboray, Katalin, Toth, Adam V., Miskolczi, Tímea D., Pesti, Krisztina, Casanova, Emilio, Kreidl, Emanuel, Mike, Arpad, Szenes, Áron, Sági, László, Lukacs, Peter

“…Agriculturally important crop plants emit a multitude of volatile organic compounds (VOCs), which are excellent indicators of their health status and their…”
Get full text

Characterization of Compound-Specific, Concentration-Independent Biophysical Properties of Sodium Channel Inhibitor Mechanism of Action Using Automated Patch-Clamp Electrophysiology by Pesti, Krisztina, Földi, Mátyás C, Zboray, Katalin, Toth, Adam V, Lukacs, Peter, Mike, Arpad

“…We have developed an automated patch-clamp protocol that allows high information content screening of sodium channel inhibitor compounds. We have observed that…”
Get full text

An Advanced Automated Patch Clamp Protocol Design to Investigate Drug—Ion Channel Binding Dynamics by Lukacs, Peter, Pesti, Krisztina, Földi, Mátyás C., Zboray, Katalin, Toth, Adam V., Papp, Gábor, Mike, Arpad

“…Standard high throughput screening projects using automated patch-clamp instruments often fail to grasp essential details of the mechanism of action, such as…”
Get full text

The mechanism of non‐blocking inhibition of sodium channels revealed by conformation‐selective photolabeling by Földi, Mátyás C., Pesti, Krisztina, Zboray, Katalin, Toth, Adam V., Hegedűs, Tamás, Málnási‐Csizmadia, András, Lukacs, Peter, Mike, Arpad

“…Background and Purpose Sodium channel inhibitors can be used to treat hyperexcitability‐related diseases, including epilepsies, pain syndromes, neuromuscular…”
Get full text