Search Results - "Téllez, Jair"

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  1. 1

    Drug transporter and oxidative stress gene expression in human macrophages infected with benznidazole-sensitive and naturally benznidazole-resistant Trypanosoma cruzi parasites treated with benznidazole by Téllez, Jair, Romero, Ibeth, Romanha, Alvaro José, Steindel, Mario

    Published in Parasites & vectors (24-05-2019)
    “…Chagas disease is a potentially life-threatening disease caused by the protozoan parasite Trypanosoma cruzi. Current therapeutic management is limited to…”
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    Journal Article
  2. 2

    Anti-SpCas9 IgY Polyclonal Antibodies Production for CRISPR Research Use by León, Esteban, Ortiz, Valentina, Pérez, Alexander, Téllez, Jair, Díaz, Gonzalo J., Ramírez H, María H., Contreras R, Luis E.

    Published in ACS omega (19-09-2023)
    “…The CRISPR/Cas adaptative immune system has been harnessed as an RNA-guided, programmable genome editing tool, allowing for diverse biotechnological…”
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    Journal Article
  3. 3

    Transsulfuration is an active pathway for cysteine biosynthesis in Trypanosoma rangeli by Romero, Ibeth, Téllez, Jair, Eiko Yamanaka, Lais, Steindel, Mario, José Romanha, Alvaro, Carlos Grisard, Edmundo

    Published in Parasites & vectors (24-04-2014)
    “…BACKGROUND: Cysteine, a sulfur-containing amino acid, plays an important role in a variety of cellular functions such as protein biosynthesis, methylation, and…”
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    Journal Article
  4. 4

    Viability and burden of Leishmania in extralesional sites during human dermal leishmaniasis by Romero, Ibeth, Téllez, Jair, Suárez, Yazmín, Cardona, Maria, Figueroa, Roger, Zelazny, Adrian, Gore Saravia, Nancy

    Published in PLoS neglected tropical diseases (14-09-2010)
    “…The clinical and epidemiological significance of Leishmania DNA in extralesional sites is obscured by uncertainty of whether the DNA derives from viable…”
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    Journal Article
  5. 5

    Prediction of potential cysteine synthase inhibitors of Leishmania braziliensis and Leishmania major parasites by computational screening by Téllez, Jair, Amarillo, Alejandra, Suarez, Carolina, Cardozo, Carlos, Guerra, Diego, Ochoa, Rodrigo, Muskus, Carlos, Romero, Ibeth

    Published in Acta tropica (01-01-2022)
    “…•Virtual screening allowed us to predict potential new CS inhibitors for Leishmania parasites.•The ZINC16524774 compound predicted to have a high affinity for…”
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    Journal Article
  6. 6

    Upregulation of Cysteine Synthase and Cystathionine β-Synthase Contributes to Leishmania braziliensis Survival under Oxidative Stress by Romero, Ibeth, Téllez, Jair, Romanha, Alvaro José, Steindel, Mario, Grisard, Edmundo Carlos

    Published in Antimicrobial agents and chemotherapy (01-08-2015)
    “…Cysteine metabolism is considered essential for the crucial maintenance of a reducing environment in trypanosomatids due to its importance as a precursor of…”
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    Journal Article
  7. 7

    Knockdown of Host Antioxidant Defense Genes Enhances the Effect of Glucantime on Intracellular Leishmania braziliensis in Human Macrophages by Téllez, Jair, Romero, Ibeth, Soares, Maurilio José, Steindel, Mario, Romanha, Alvaro José

    Published in Antimicrobial agents and chemotherapy (01-07-2017)
    “…Leishmaniasis is a neglected tropical disease that affects millions of people worldwide and represents a major public health problem. Information on protein…”
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    Journal Article
  8. 8

    Use of liposomal nanoformulations in antileishmania therapy: challenges and perspectives by Téllez, Jair, Echeverry, Maria Clara, Romero, Ibeth, Guatibonza, Andrea, Santos Ramos, Guilherme, Borges De Oliveira, Ana Carolina, Frézard, Frédéric, Demicheli, Cynthia

    Published in Journal of liposome research (03-04-2021)
    “…Leishmaniasis is a parasitic disease treatable and curable, however, the chemotherapeutic agents for their treatment are limited. In South American countries,…”
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    Journal Article
  9. 9

    Lupeol acetate and alpha-amyrin terpenes activity against 'Trypanosoma cruzi': Insights into toxicity and potential mechanisms of action by Pardo-Rodriguez, Daniel, Cifuentes-López, Andres, Bravo-Espejo, Juan, Romero, Ibeth, Robles, Jorge, Cuervo, Claudia, Mejía, Sol M., Tellez, Jair

    Published in Tropical medicine and infectious disease (03-05-2023)
    “…Background: Chagas disease is a potentially fatal disease caused by the parasite 'Trypanosoma cruzi'. There is growing scientific interest in finding new and…”
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    Journal Article
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    Nanoencapsulamiento como estrategia para mejorar la entrega de medicamentos para el tratamiento de enfermedades infecciosas: una visión general by Tellez Meneses, Jair Alexander

    Published in Revista Colombiana de biotecnologia (31-01-2022)
    “…El control quimioterapéutico es una de las principales formas de combatir las enfermedades infecciosas, sin embargo, existen varias limitaciones que ponen en…”
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    Journal Article
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    Biological characterization of Trypanosoma cruzi stocks from domestic and sylvatic vectors in Sierra Nevada of Santa Marta, Colombia by Téllez-Meneses, Jair, Mejía-Jaramillo, Ana María, Triana-Chávez, Omar

    Published in Acta tropica (01-10-2008)
    “…Sierra Nevada of Santa Marta is one of the most endemic regions of Chagas disease in Colombia. In this study, we compared the biological behavior and genetic…”
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    Journal Article
  14. 14

    Lupeol Acetate and α-Amyrin Terpenes Activity against ITrypanosoma cruzi/I: Insights into Toxicity and Potential Mechanisms of Action by Pardo-Rodriguez, Daniel, Cifuentes-López, Andres, Bravo-Espejo, Juan, Romero, Ibeth, Robles, Jorge, Cuervo, Claudia, Mejía, Sol M, Tellez, Jair

    Published in Tropical medicine and infectious disease (01-05-2023)
    “…Background: Chagas disease is a potentially fatal disease caused by the parasite Trypanosoma cruzi. There is growing scientific interest in finding new and…”
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    Journal Article
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