Search Results - "TÖRN, Carina"

Presence of GAD Antibodies During Gestational Diabetes Mellitus Predicts Type 1 Diabetes by Nilsson, Charlotta, Ursing, Dag, Törn, Carina, Aberg, Anders, Landin-Olsson, Mona

“…Presence of GAD Antibodies During Gestational Diabetes Mellitus Predicts Type 1 Diabetes Charlotta Nilsson , MD 1 , Dag Ursing , MD 1 , Carina Törn , BSC, PHD…”
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β-cell function and metabolic control in latent autoimmune diabetes in adults with early insulin versus conventional treatment: a 3-year follow-up by Thunander, Maria, Thorgeirsson, Hlin, Törn, Carina, Petersson, Christer, Landin-Olsson, Mona

“…ObjectivesThe optimal treatment of latent autoimmune diabetes in adults (LADA) is not established. We explored whether early insulin treatment, which has shown…”
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Long-Term GAD-alum Treatment Effect on Different T-Cell Subpopulations in Healthy Children Positive for Multiple Beta Cell Autoantibodies by Salami, Falastin, Spiliopoulos, Lampros, Maziarz, Marlena, Lundgren, Markus, Brundin, Charlotte, Bennet, Rasmus, Hillman, Magnus, Törn, Carina, Elding Larsson, Helena

“…Objective. The objective of this study was to explore whether recombinant GAD65 conjugated hydroxide (GAD-alum) treatment affected peripheral blood T-cell…”
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Complete blood counts with red blood cell determinants associate with reduced beta‐cell function in seroconverted Swedish TEDDY children by Salami, Falastin, N.Tamura, Roy, Elding Larsson, Helena, Lernmark, Åke, Törn, Carina

“…Objectives To investigate whether changes in complete blood count (CBC) in islet autoantibody positive children with increased genetic risk for type 1 diabetes…”
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Role of Type 1 Diabetes-Associated SNPs on Risk of Autoantibody Positivity in the TEDDY Study by Törn, Carina, Hadley, David, Lee, Hye-Seung, Hagopian, William, Lernmark, Åke, Simell, Olli, Rewers, Marian, Ziegler, Anette, Schatz, Desmond, Akolkar, Beena, Onengut-Gumuscu, Suna, Chen, Wei-Min, Toppari, Jorma, Mykkänen, Juha, Ilonen, Jorma, Rich, Stephen S, She, Jin-Xiong, Steck, Andrea K, Krischer, Jeffrey

“…The Environmental Determinants of Diabetes in the Young (TEDDY) study prospectively follows 8,677 children enrolled from birth who carry HLA-susceptibility…”
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Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study by Lönnrot, Maria, Lynch, Kristian F., Elding Larsson, Helena, Lernmark, Åke, Rewers, Marian J., Törn, Carina, Burkhardt, Brant R., Briese, Thomas, Hagopian, William A., She, Jin-Xiong, Simell, Olli G., Toppari, Jorma, Ziegler, Anette-G., Akolkar, Beena, Krischer, Jeffrey P., Hyöty, Heikki

“…Aims/hypothesis Respiratory infections and onset of islet autoimmunity are reported to correlate positively in two small prospective studies. The Environmental…”
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Evaluation of the RSR 3 screen ICA™ and 2 screen ICA™ as screening assays for type 1 diabetes in Sweden by Törn, Carina, Vaziri-Sani, Fariba, Ramelius, Anita, Elding Larsson, Helena, Ivarsson, Sten Anders, Amoroso, Marie, Furmaniak, Jadwiga, Powell, Michael, Smith, Bernard Rees

“…Aim The study aim was to evaluate the RSR 3 Screen ICA™ and 2 Screen ICA™ for detection of islet cell autoimmunity in healthy Swedish subjects and patients…”
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Autoantibodies in Pandemrix®-induced narcolepsy: Nine candidate autoantigens fail the conformational autoantibody test by Wallenius, Madeleine, Lind, Alexander, Akel, Omar, Karlsson, Emma, Svensson, Markus, Arvidsson, Elin, Ramelius, Anita, Törn, Carina, Palm, Lars, Lernmark, Åke, Elding Larsson, Helena

“…Study objectives: Narcolepsy type 1 (NT1) is a chronic sleep disorder characterized by loss of hypocretin-producing neurons. Increased NT1 incidence was…”
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Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort by Sharma, Ashok, Liu, Xiang, Hadley, David, Hagopian, William, Chen, Wei-Min, Onengut-Gumuscu, Suna, Törn, Carina, Steck, Andrea K., Frohnert, Brigitte I., Rewers, Marian, Ziegler, Anette-G., Lernmark, Åke, Toppari, Jorma, Krischer, Jeffrey P., Akolkar, Beena, Rich, Stephen S., She, Jin-Xiong

“…Traditional linkage analysis and genome-wide association studies have identified HLA and a number of non-HLA genes as genetic factors for islet autoimmunity…”
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Levels of C-peptide, body mass index and age, and their usefulness in classification of diabetes in relation to autoimmunity, in adults with newly diagnosed diabetes in Kronoberg, Sweden by Thunander, Maria, Törn, Carina, Petersson, Christer, Ossiansson, Birger, Fornander, Jan, Landin-Olsson, Mona

“…ObjectiveC-peptide is a main outcome measure in treatment trials of diabetes. C-peptide also has a role in the classification of diabetes, which is often…”
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HbA1c as a time predictive biomarker for an additional islet autoantibody and type 1 diabetes in seroconverted TEDDY children by Salami, Falastin, Tamura, Roy, You, Lu, Lernmark, Åke, Larsson, Helena Elding, Lundgren, Markus, Krischer, Jeffrey, Ziegler, Anette‐Gabriele, Toppari, Jorma, Veijola, Riitta, Rewers, Marian, Haller, Michael J., Hagopian, William, Akolkar, Beena, Törn, Carina

“…Objective Increased level of glycated hemoglobin (HbA1c) is associated with type 1 diabetes onset that in turn is preceded by one to several autoantibodies…”
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Gestational respiratory infections interacting with offspring HLA and CTLA-4 modifies incident β-cell autoantibodies by Lynch, Kristian F., Lee, Hye-Seung, Törn, Carina, Vehik, Kendra, Krischer, Jeffrey P., Larsson, Helena Elding, Haller, Michael J., Hagopian, William A., Rewers, Marian J., She, Jin-Xiong, Simell, Olli G., Toppari, Jorma, Ziegler, Anette-G., Akolkar, Beena, Hyöty, Heikki, Bonifacio, Ezio, Lernmark, Åke

“…β-cell autoantibodies against insulin (IAA), GAD65 (GADA) and IA-2 (IA-2A) precede onset of childhood type 1 diabetes (T1D). Incidence of the first appearing…”
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Autoimmunity against INS-IGF2 Protein Expressed in Human Pancreatic Islets by Kanatsuna, Norio, Taneera, Jalal, Vaziri-Sani, Fariba, Wierup, Nils, Larsson, Helena Elding, Delli, Ahmed, Skärstrand, Hanna, Balhuizen, Alexander, Bennet, Hedvig, Steiner, Donald F., Törn, Carina, Fex, Malin, Lernmark, Åke

“…Islet INS-IGF2 was examined as a possible autoantigen in type 1 diabetes. Results: INS-IGF2 expression was inversely related to donor HbA1c and…”
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Childhood screening for type 1 diabetes comparing automated multiplex Antibody Detection by Agglutination-PCR (ADAP) with single plex islet autoantibody radiobinding assays by Lind, Alexander, Freyhult, Eva, de Jesus Cortez, Felipe, Ramelius, Anita, Bennet, Rasmus, Robinson, Peter V., Seftel, David, Gebhart, David, Tandel, Devangkumar, Maziarz, Marlena, Larsson, Helena Elding, Lundgren, Markus, Carlsson, Annelie, Nilsson, Anna-Lena, Fex, Malin, Törn, Carina, Agardh, Daniel, Tsai, Cheng-ting, Lernmark, Åke, Persson, Martina, Forsander, Gun, Ludvigsson, Johnny, Samuelsson, Ulf, Marcus, Claude

“…Two or more autoantibodies against either insulin (IAA), glutamic acid decarboxylase (GADA), islet antigen-2 (IA-2A) or zinc transporter 8 (ZnT8A) denote stage…”
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An Increased Diagnostic Sensitivity of Truncated GAD65 Autoantibodies in Type 1 Diabetes May Be Related to HLA-DQ8 by Wester, Axel, Skärstrand, Hanna, Lind, Alexander, Ramelius, Anita, Carlsson, Annelie, Cedervall, Elisabeth, Jönsson, Björn, Ivarsson, Sten A, Elding Larsson, Helena, Larsson, Karin, Lindberg, Bengt, Neiderud, Jan, Fex, Malin, Törn, Carina, Lernmark, Åke

“…N-terminally truncated (96-585) GAD65 (tGAD65) autoantibodies may better delineate type 1 diabetes than full-length GAD65 (fGAD65) autoantibodies. We aimed to…”
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Beta cell function in participants with single or multiple islet autoantibodies at baseline in the TEDDY Family Prevention Study: TEFA by Martinez, Maria Månsson, Salami, Falastin, Larsson, Helena Elding, Toppari, Jorma, Lernmark, Åke, Kero, Jukka, Veijola, Riitta, Koskenniemi, Jaakko J, Tossavainen, Päivi, Lundgren, Markus, Borg, Henrik, Katsarou, Anastasia, Maziarz, Marlena, Törn, Carina

“…Aim The aim of the present study was to assess beta cell function based on an oral glucose tolerance test (OGTT) in participants with single islet autoantibody…”
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lack of anti-idiotypic antibodies, not the presence of the corresponding autoantibodies to glutamate decarboxylase, defines type 1 diabetes by Oak, Shilpa, Gilliam, Lisa K, Landin-Olsson, Mona, Törn, Carina, Kockum, Ingrid, Pennington, Christina R, Rowley, Merrill J, Christie, Michael R, Banga, J. Paul, Hampe, Christiane S

“…Autoantibodies to glutamate decarboxylase 65 (GAD65Ab) are commonly believed to be a major characteristic for type 1 diabetes (T1D). We investigated the…”
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HLA genes, islet autoantibodies and residual C-peptide at the clinical onset of type 1 diabetes mellitus and the risk of retinopathy 15 years later by Jensen, Richard A, Agardh, Elisabet, Lernmark, Ake, Gudbjörnsdottir, Soffia, Smith, Nicholas L, Siscovick, David S, Törn, Carina

“…HLA genes, islet autoantibodies and residual C-peptide were studied to determine the independent association of each exposure with diabetic retinopathy (DR),…”
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Elevated Serum GAD65 and GAD65-GADA Immune Complexes in Stiff Person Syndrome by Gu Urban, Gucci Jijuan, Friedman, Mikaela, Ren, Ping, Törn, Carina, Fex, Malin, Hampe, Christiane S., Lernmark, Åke, Landegren, Ulf, Kamali-Moghaddam, Masood

“…Glutamic acid decarboxylase 65 (GAD65) and autoantibodies specific for GAD65 (GADA) are associated with autoimmune diseases including Stiff Person Syndrome…”
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ZnT8 autoantibody titers in type 1 diabetes patients decline rapidly after clinical onset by Vaziri-Sani, Fariba, Oak, Shilpa, Radtke, Jared, Lernmark, ke, Lynch, Kristian, Agardh, Carl.-D., Cilio, Corrado M., Lethagen, sa L., Örtqvist, Eva, Landin-Olsson, Mona, Törn, Carina, Hampe, Christiane S.

“…Autoantibodies to the islet-specific zinc transporter isoform 8 (ZnT8) are detected in the majority of type 1 diabetes patients prior to and at clinical…”
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