Search Results - "TÖRN, C"

Diabetes Antibody Standardization Program: evaluation of assays for autoantibodies to glutamic acid decarboxylase and islet antigen-2 by Törn, C, Mueller, P. W, Schlosser, M, Bonifacio, E, Bingley, P. J

“…Aims/hypothesis Islet autoantibodies are important in diabetes classification and risk assessment, and as endpoints in observational studies. The Diabetes…”
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Diabetes Antibody Standardization Program: evaluation of assays for insulin autoantibodies by Schlosser, M, Mueller, P. W, Törn, C, Bonifacio, E, Bingley, P. J

“…Aims/hypothesis Insulin autoantibodies (IAA) are important in type 1 diabetes risk assessment. However, their determination varies more between laboratories…”
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No evidence of association of the PDCD1 gene with Type 1 diabetes by Fawwaz, S., Nikamo, P., Törn, C., Landin-Olsson, M., Lernmark, Å., Alarcón-Riquelme, M., Kockum, I.

“…Aims  To test the association between the immunoreceptor PD‐1 (PDCD1) gene and Type 1 diabetes mellitus (T1DM). This gene has been reported to be associated…”
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Country-specific birth weight and length in type 1 diabetes high-risk HLA genotypes in combination with prenatal characteristics by Sterner, Y, Törn, C, Lee, H-S, Larsson, H, Winkler, C, McLeod, W, Lynch, K, Simell, O, Ziegler, A, Schatz, D, Hagopian, W, Rewers, M, She, J-X, Krischer, J P, Akolkar, B, Lernmark, Å

“…Objective: To examine the relationship between high-risk human leukocyte antigen (HLA) genotypes for type 1 diabetes and birth size in combination with…”
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glutamic acid decarboxylase 65 immunoglobulin G subclass profile differs between adult-onset type 1 diabetes and latent autoimmune diabetes in adults (LADA) up to 3 years after clinical onset by Hillman, M, Törn, C, Landin-Olsson, M

“…Autoantibodies against glutamic acid decarboxylase 65 (GADA) are found frequently in patients with autoimmune diabetes. Immunoglobulin (Ig)G₁ is the most…”
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Prognostic factors for the course of β cell function in autoimmune diabetes by TÖRN, C, LANDIN-OLSSON, M, SUNDKVIST, G, WIBELL, L, ÖSTMAN, J, LERNMARK, A, PALMER, J. P, ARNQVIST, H. J, BLOHME, G, LITHNER, F, LITTORIN, B, NYSTRÖM, L, SCHERSTEN, B

“…This study presents a 2-yr follow-up of 281 patients, aged 15-34 yr, diagnosed with diabetes between 1992 and 1993. At diagnosis, 224 (80%) patients were…”
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Determination of glutamic acid decarboxylase antibodies (GADA) IgG subclasses - comparison of three immunoprecipitation assays (IPAs) by Hillman, M, Törn, C, Landin-Olsson, M

“…IgG subclasses of glutamic acid decarboxylase (GAD₆₅) antibodies (GADA) may reflect the immunological state in the pancreas of GADA-positive patients with…”
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Islet cell autoantibody levels after the diagnosis of young adult diabetic patients by Jensen, R., Gilliam, L., Torn, C., Landin-Olsson, M., Palmer, J., Åkesson, K., Kockum, I., Lernmark, B., Karlsson, A. F., Lynch, K. F., Breslow, N., Lernmark, Å., Sundkvist, G.

“…Aims  The aim was to determine the course of islet cell antibodies [glutamate decarboxylase (GADA), tyrosine phosphatase‐like islet antigen 2 (IA‐2A) and islet…”
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IgG4-subclass of glutamic acid decarboxylase antibody is more frequent in latent autoimmune diabetes in adults than in type 1 diabetes by HILLMAN, M, TÖRN, C, THORGEIRSSON, H, LANDIN-OLSSON, M

“…Glutamic acid decarboxylase autoantibodies (GADA) are the most frequent beta-cell-specific autoantibodies in type 1 diabetes and in latent autoimmune diabetes…”
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Incidence of type 1 and type 2 diabetes in adults and children in Kronoberg, Sweden by Thunander, M, Petersson, C, Jonzon, K, Fornander, J, Ossiansson, B, Torn, C, Edvardsson, S, Landin-Olsson, M

“…Abstract All newly diagnosed diabetes in Kronoberg during 3 years was registered, with blood samples from 1630/1666 (97.8%) adults. Those positive for GADab…”
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Doubly Reactive INS‐IGF2 Autoantibodies in Children with Newly Diagnosed Autoimmune (type 1) Diabetes by Kanatsuna, N., Delli, A., Andersson, C., Nilsson, A.‐L., Vaziri‐Sani, F., Larsson, K., Carlsson, A., Cedervall, E., Jönsson, B., Neiderud, J., Elding Larsson, H., Ivarsson, S.‐A., Törn, C., Fex, M., Lernmark, Å.

“…The splice variant INS‐IGF2 entails the preproinsulin signal peptide, the insulin B‐chain, eight amino acids of the C‐peptide and 138 unique amino acids from…”
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Species-specific autoantibodies in type 1 diabetes by HAMPE, C. S, ÖRTQVIST, E, ROLANDSSON, O, LANDIN-OLSSON, M, TÖRN, C, AGREN, A, PERSSON, B, SCHRANZ, D. B, LERNMARK, A

“…GAD65 autoantibodies (GAD65Ab) are important markers for type 1 (insulin-dependent) diabetes mellitus. Although most patients have GAD65Ab at the time of…”
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Ketoacidosis in young adults is not related to the islet antibodies at the diagnosis of Type 1 diabetes mellitus - a nationwide study by Östman, J., Landin-Olsson, M., Törn, C., Palmer, J., Lernmark, Å., Arnqvist, H., Björk, E., Bolinder, J., Blohmé, G., Eriksson, J., Littorin, B., Nyström, L., Scherstén, B., Sundkvist, G., Wibell, L.

“…Aims To test the hypothesis that there is lower prevalence of islet antibodies in subjects with newly diagnosed Type 1 diabetes mellitus in young adulthood…”
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Combinations of Beta Cell Specific Autoantibodies at Diagnosis of Diabetes in Young Adults Reflects Different Courses of Beta Cell Damage by Törn, C., Landin-Olsson, M., Lernmark, A., Scherstén, B., Östman, J., Arnqvist, H. J., Björk, E., Blohmé, G., Bolinder, J., Eriksson, J., Littorini, B., Nyström, L., Sundkvist, G.

“…To explore the natural course of beta cell function in recent onset diabetes, a subgroup (n=157) of all incident cases (n=879) 15-34 years old, 1992-1993 in…”
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Immunoglobulin Subclass Profiles of Anti‐idiotypic Antibodies to GAD65Ab Differ Between Type 1 Diabetes Patients and Healthy Individuals by Oak, S., Radtke, J., Törn, C., Landin‐Olsson, M., Hampe, C. S.

“…Previously we reported the presence of anti‐idiotypic antibodies (anti‐Id)‐specific to autoantibodies against GAD65 (GAD65Ab) in healthy individuals while the…”
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A simple and rapid microSepharose assay for GAD65 and ICA512 autoantibodies in diabetes by Schranz, Dorota B, Bekris, Lynn, Landin-Olsson, Mona, Törn, Carina, Niläng, Anna, Toll, Åsa, Grönlund, Hans, Toivola, Bert, Lernmark, Åke

“…GAD65Ab and ICA512Ab are strongly associated with insulin-dependent (Type 1) diabetes mellitus. A novel, simple radio-antigen binding assay with microSepharose…”
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Islet cell antibodies represent autoimmune response against several antigens by Månsson, L, Törn, C, Landin-Olsson, M

“…To study the antigens involved in the islet cell antibody (ICA) reaction we selected 30 patient serum samples (ten in each group) positive for ICA and one…”
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Prognostic Factors for the Course of   Cell Function in Autoimmune Diabetes by Torn, C.

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Species-Specific Autoantibodies in Type 1 Diabetes1 by Hampe, C. S, Örtqvist, E, Rolandsson, O, Landin-Olsson, M, Törn, C, Ågren, Å, Persson, B, Schranz, D. B, Lernmark, Å

“…GAD65 autoantibodies (GAD65Ab) are important markers for type 1 (insulin-dependent) diabetes mellitus. Although most patients have GAD65Ab at the time of…”
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Normal weight promotes remission and low number of islet antibodies prolong the duration of remission in Type 1 diabetes by Schölin, A., Törn, C., Nyström, L., Berne, C., Arnqvist, H., Blohmé, G., Bolinder, J., Eriksson, J. W., Kockum, I., Landin-Olsson, M., Östman, J., Karlsson, F. A., Sundkvist, G., Björk, E.

“…Aim  To identify clinical, immunological and biochemical factors that predict remission, and its duration in a large cohort of young adults with Type 1…”
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