Search Results - "T'Kindt, Ruben"

Profiling and Characterizing Skin Ceramides Using Reversed-Phase Liquid Chromatography–Quadrupole Time-of-Flight Mass Spectrometry by t’Kindt, Ruben, Jorge, Lucie, Dumont, Emmie, Couturon, Pauline, David, Frank, Sandra, Pat, Sandra, Koen

“…An LC-MS based method for the profiling and characterization of ceramide species in the upper layer of human skin is described. Ceramide samples, collected by…”
Get full text

Joint GC–MS and LC–MS platforms for comprehensive plant metabolomics: Repeatability and sample pre-treatment by t’Kindt, Ruben, Morreel, Kris, Deforce, Dieter, Boerjan, Wout, Van Bocxlaer, Jan

“…Metabolomics nowadays mostly comprises the application of both LC–MS and GC–MS based approaches. Here we investigate different extraction set-ups for these two…”
Get full text

Untargeted Lipidomic Analysis in Chronic Obstructive Pulmonary Disease: Uncovering Sphingolipids by TELENGA, Eef D, HOFFMANN, Roland F, POSTMA, Dirkje S, SANDRA, Koen, TEN HACKEN, Nick H. T, T'KINDT, Ruben, HOONHORST, Susan J. M, WILLEMSE, Brigitte W. M, VAN OOSTERHOUT, Antoon J. M, HEIJINK, Irene H, VAN DEN BERGE, Maarten, JORGE, Lucie, SANDRA, Pat

“…Cigarette smoke is the major risk factor in the development of chronic obstructive pulmonary disease (COPD). Lipidomics is a novel and emerging research field…”
Get full text

2-Methyl-pentanoyl-carnitine (2-MPC): a urine biomarker for patent Ascaris lumbricoides infection by Lagatie, Ole, Verheyen, Ann, Van Asten, Stijn, Odiere, Maurice R., Djuardi, Yenny, Levecke, Bruno, Vlaminck, Johnny, Mekonnen, Zeleke, Dana, Daniel, T’Kindt, Ruben, Sandra, Koen, van Outersterp, Rianne, Oomens, Jos, Lin, Ronghui, Dillen, Lieve, Vreeken, Rob, Cuyckens, Filip, Stuyver, Lieven J.

“…Infections with intestinal worms, such as Ascaris lumbricoides, affect hundreds of millions of people in all tropical and subtropical regions of the world…”
Get full text

Profiling over 1500 Lipids in Induced Lung Sputum and the Implications in Studying Lung Diseases by t’Kindt, Ruben, Telenga, Eef D, Jorge, Lucie, Van Oosterhout, Antoon J. M, Sandra, Pat, Ten Hacken, Nick H. T, Sandra, Koen

“…Induced lung sputum is a valuable matrix in the study of respiratory diseases. Although the methodology of sputum collection has evolved to a point where it is…”
Get full text

Metabolomics to unveil and understand phenotypic diversity between pathogen populations by t'Kindt, Ruben, Scheltema, Richard A, Jankevics, Andris, Brunker, Kirstyn, Rijal, Suman, Dujardin, Jean-Claude, Breitling, Rainer, Watson, David G, Coombs, Graham H, Decuypere, Saskia

“…Leishmaniasis is a debilitating disease caused by the parasite Leishmania. There is extensive clinical polymorphism, including variable responsiveness to…”
Get full text

LC–MS metabolic profiling of Arabidopsis thaliana plant leaves and cell cultures: Optimization of pre-LC–MS procedure parameters by t’Kindt, Ruben, De Veylder, Lieven, Storme, Michael, Deforce, Dieter, Van Bocxlaer, Jan

“…This study treats the optimization of methods for homogenizing Arabidopsis thaliana plant leaves as well as cell cultures, and extracting their metabolites for…”
Get full text

Towards an unbiased metabolic profiling of protozoan parasites: optimisation of a Leishmania sampling protocol for HILIC-orbitrap analysis by t’Kindt, Ruben, Jankevics, Andris, Scheltema, Richard A., Zheng, Liang, Watson, David G., Dujardin, Jean-Claude, Breitling, Rainer, Coombs, Graham H., Decuypere, Saskia

“…Comparative metabolomics of Leishmania species requires the simultaneous identification and quantification of a large number of intracellular metabolites…”
Get full text

The potential of metabolomics for Leishmania research in the post-genomics era by Scheltema, Richard A, Decuypere, Saskia, T'kindt, Ruben, Dujardin, Jean-Claude, Coombs, Graham H, Breitling, Rainer

“…The post-genomics era has provided researchers with access to a new generation of tools for the global characterization and understanding of pathogen…”
Get more information

Evaluation of hydrophilic interaction chromatography versus reversed-phase chromatography in a plant metabolomics perspective by t'Kindt, Ruben, Storme, Michael, Deforce, Dieter, Van Bocxlaer, Jan

“…The metabolomics goal, the unbiased relative quantification of all metabolites in a biological system, still lacks a universal analytical approach. In the…”
Get full text

Erratum to: Towards an unbiased metabolic profiling of protozoan parasites: optimisation of a Leishmania sampling protocol for HILIC-orbitrap analysis by t’Kindt, Ruben, Jankevics, Andris, Scheltema, Richard A., Zheng, Liang, Watson, David G., Dujardin, Jean-Claude, Breitling, Rainer, Coombs, Graham H., Decuypere, Saskia

Get full text

Multimodal biomarker discovery for active Onchocerca volvulus infection by Lagatie, Ole, Njumbe Ediage, Emmanuel, Van Roosbroeck, Dirk, Van Asten, Stijn, Verheyen, Ann, Batsa Debrah, Linda, Debrah, Alex, Odiere, Maurice R, T'Kindt, Ruben, Dumont, Emmie, Sandra, Koen, Dillen, Lieve, Verhaeghe, Tom, Vreeken, Rob, Cuyckens, Filip, Stuyver, Lieven J

“…The neglected tropical disease onchocerciasis, or river blindness, is caused by infection with the filarial nematode Onchocerca volvulus. Current estimates…”
Get full text

Improved analyte detectability of proteins and peptide lysates by means of multiple large-volume injection in LC-MS by Storme, Michael L, t'Kindt, Ruben S, Van Bocxlaer, Jan F

“…A 'multiple (trapping) large-volume injection' approach was developed for the analysis of peptides and proteins. In this way, a maximally 10-fold gain in…”
Get full text

Psoralen and Ultraviolet A Light Treatment Directly Affects Phosphatidylinositol 3-Kinase Signal Transduction by Altering Plasma Membrane Packing by Van Aelst, Britt, Devloo, Rosalie, Zachée, Pierre, t'Kindt, Ruben, Sandra, Koen, Vandekerckhove, Philippe, Compernolle, Veerle, Feys, Hendrik B.

“…Psoralen and ultraviolet A light (PUVA) are used to kill pathogens in blood products and as a treatment of aberrant cell proliferation in dermatitis, cutaneous…”
Get full text

Cov-MS: A Community-Based Template Assay for Mass-Spectrometry-Based Protein Detection in SARS-CoV-2 Patients by Van Puyvelde, Bart, Van Uytfanghe, Katleen, Tytgat, Olivier, Van Oudenhove, Laurence, Gabriels, Ralf, Bouwmeester, Robbin, Daled, Simon, Van Den Bossche, Tim, Ramasamy, Pathmanaban, Verhelst, Sigrid, De Clerck, Laura, Corveleyn, Laura, Willems, Sander, Debunne, Nathan, Wynendaele, Evelien, De Spiegeleer, Bart, Judak, Peter, Roels, Kris, De Wilde, Laurie, Van Eenoo, Peter, Reyns, Tim, Cherlet, Marc, Dumont, Emmie, Debyser, Griet, t’Kindt, Ruben, Sandra, Koen, Gupta, Surya, Drouin, Nicolas, Harms, Amy, Hankemeier, Thomas, Jones, Donald J. L., Gupta, Pankaj, Lane, Dan, Lane, Catherine S., El Ouadi, Said, Vincendet, Jean-Baptiste, Morrice, Nick, Oehrle, Stuart, Tanna, Nikunj, Silvester, Steve, Hannam, Sally, Sigloch, Florian C., Bhangu-Uhlmann, Andrea, Claereboudt, Jan, Anderson, N. Leigh, Razavi, Morteza, Degroeve, Sven, Cuypers, Lize, Stove, Christophe, Lagrou, Katrien, Martens, Geert A., Deforce, Dieter, Martens, Lennart, Vissers, Johannes P. C., Dhaenens, Maarten

“…Rising population density and global mobility are among the reasons why pathogens such as SARS-CoV-2, the virus that causes COVID-19, spread so rapidly across…”
Get full text

Lipidomics of tobacco leaf and cigarette smoke by Dunkle, Melissa N., Yoshimura, Yuta, t⿿Kindt, Ruben, Ortiz, Alexia, Masugi, Eri, Mitsui, Kazuhisa, David, Frank, Sandra, Pat, Sandra, Koen

“…⿢Lipidomics study of cured tobacco leaf and cigarette smoke is described.⿢Automated fractionation increases lipidome coverage and allows large-scale…”
Get full text

Evaluation of hydrophilic interaction chromatography versus reversed-phase chromatography in a plant metabolomics perspective: Hydrophilic interaction chromatography by T'KINDT, Ruben, STORME, Michael, DEFORCE, Dieter, VAN BOCXLAER, Jan

Get full text

LC-MS metabolic profiling ofArabidopsis thaliana plant leaves and cell cultures : Optimization of pre-LC-MS procedure parameters by T'KINDT, Ruben, DE VEYLDER, Lieven, STORME, Michael, DEFORCE, Dieter, VAN BOCXLAER, Jan

Get full text

Broad-spectrum separations in metabolomics using enhanced polar LC stationary phases: A dedicated evaluation using plant metabolites by t'Kindt, Ruben, Alaerts, Goedele, Vander Heyden, Yvan, Deforce, Dieter, Van Bocxlaer, Jan

“…In metabolomics, major efforts are invested in the development of suitable analytical approaches. A tendency towards the use of LC-MS is nowadays very obvious…”
Get full text