Search Results - "Szymonifka, Jackie"

Static and dynamic assessment of myocardial perfusion by computed tomography by Danad, Ibrahim, Szymonifka, Jackie, Schulman-Marcus, Joshua, Min, James K

“…Recent developments in computed tomography (CT) technology have fulfilled the prerequisites for the clinical application of myocardial CT perfusion (CTP)…”
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Effect of Neprilysin Inhibition on Various Natriuretic Peptide Assays by Ibrahim, Nasrien E., McCarthy, Cian P., Shrestha, Shreya, Gaggin, Hanna K., Mukai, Renata, Szymonifka, Jackie, Apple, Fred S., Burnett, John C., Iyer, Seethalakshmi, Januzzi, James L.

“…With sacubitril/valsartan treatment, B-type natriuretic peptide (BNP) concentrations increase; it remains unclear whether change in BNP concentrations is…”
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Preliminary results of a phase II trial of proton radiotherapy for pediatric rhabdomyosarcoma by Ladra, Matthew M, Szymonifka, Jackie D, Mahajan, Anita, Friedmann, Alison M, Yong Yeap, Beow, Goebel, Claire P, MacDonald, Shannon M, Grosshans, David R, Rodriguez-Galindo, Carlos, Marcus, Karen J, Tarbell, Nancy J, Yock, Torunn I

“…This prospective phase II study was designed to assess disease control and to describe acute and late adverse effects of treatment with proton radiotherapy in…”
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Identification of Three Rheumatoid Arthritis Disease Subtypes by Machine Learning Integration of Synovial Histologic Features and RNA Sequencing Data by Orange, Dana E., Agius, Phaedra, DiCarlo, Edward F., Robine, Nicolas, Geiger, Heather, Szymonifka, Jackie, McNamara, Michael, Cummings, Ryan, Andersen, Kathleen M., Mirza, Serene, Figgie, Mark, Ivashkiv, Lionel B., Pernis, Alessandra B., Jiang, Caroline S., Frank, Mayu O., Darnell, Robert B., Lingampali, Nithya, Robinson, William H., Gravallese, Ellen, Bykerk, Vivian P., Goodman, Susan M., Donlin, Laura T.

“…Objective In this study, we sought to refine histologic scoring of rheumatoid arthritis (RA) synovial tissue by training with gene expression data and machine…”
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Extramedullary disease portends poor prognosis in multiple myeloma and is over-represented in high-risk disease even in the era of novel agents by USMANI, Saad Z, HEUCK, Christoph, VAN RHEE, Frits, CROWLEY, John, BARLOGIE, Bart, MITCHELL, Alan, SZYMONIFKA, Jackie, NAIR, Bijay, HOERING, Antje, ALSAYED, Yazan, WAHEED, Sarah, HAIDER, Sajjad, RESTREPO, Alejandro

“…Extramedullary disease is an uncommon manifestation in multiple myeloma and can either accompany newly diagnosed disease or develop with disease progression or…”
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Prediction of Late Disease Recurrence and Extended Adjuvant Letrozole Benefit by the HOXB13/IL17BR Biomarker by SGROI, Dennis C, CARNEY, Erin, SCHNABEL, Catherine A, ERLANDER, Mark G, INGLE, James N, PORTER, Peggy, MUSS, Hyman B, PRITCHARD, Katherine I, DONGSHENG TU, RIMM, David L, GOSS, Paul E, ZARRELLA, Elizabeth, STEFFEL, Lauren, BINNS, Shemeica N, FINKELSTEIN, Dianne M, SZYMONIFKA, Jackie, BHAN, Atul K, SHEPHERD, Lois E, YI ZHANG

“…Biomarkers to optimize extended adjuvant endocrine therapy for women with estrogen receptor (ER)-positive breast cancer are limited. The HOXB13/IL17BR (H/I)…”
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FOLFIRINOX in Locally Advanced Pancreatic Cancer: The Massachusetts General Hospital Cancer Center Experience by Faris, Jason E., Blaszkowsky, Lawrence S., McDermott, Shaunagh, Guimaraes, Alexander R., Szymonifka, Jackie, Huynh, Mai Anh, Ferrone, Cristina R., Wargo, Jennifer A., Allen, Jill N., Dias, Lauren E., Kwak, Eunice L., Lillemoe, Keith D., Thayer, Sarah P., Murphy, Janet E., Zhu, Andrew X., Sahani, Dushyant V., Wo, Jennifer Y., Clark, Jeffrey W., Fernandez‐del Castillo, Carlos, Ryan, David P., Hong, Theodore S.

“…The objective of our retrospective institutional experience is to report the overall response rate, R0 resection rate, progression‐free survival, and…”
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A dosimetric comparison of proton and intensity modulated radiation therapy in pediatric rhabdomyosarcoma patients enrolled on a prospective phase II proton study by Ladra, Matthew M, Edgington, Samantha K, Mahajan, Anita, Grosshans, David, Szymonifka, Jackie, Khan, Fazal, Moteabbed, Maryam, Friedmann, Alison M, MacDonald, Shannon M, Tarbell, Nancy J, Yock, Torunn I

“…Abstract Background Pediatric rhabdomyosarcoma (RMS) is highly curable, however, cure may come with significant radiation related toxicity in developing…”
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High-dose proton-based radiation therapy in the management of spine chordomas: outcomes and clinicopathological prognostic factors by Rotondo, Ronny L, Folkert, Wendy, Liebsch, Norbert J, Chen, Yen-Lin E, Pedlow, Frank X, Schwab, Joseph H, Rosenberg, Andrew E, Nielsen, G Petur, Szymonifka, Jackie, Ferreira, Al E, Hornicek, Francis J, DeLaney, Thomas F

“…Spinal chordomas can have high local recurrence rates after surgery with or without conventional dose radiation therapy (RT). Treatment outcomes and prognostic…”
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Validation of the Hip Disability and Osteoarthritis Outcome Score and Knee Injury and Osteoarthritis Outcome Score Pain and Function Subscales for Use in Total Hip Replacement and Total Knee Replacement Clinical Trials by Goodman, Susan M., Mehta, Bella Y., Mandl, Lisa A., Szymonifka, Jackie D., Finik, Jackie, Figgie, Mark P., Navarro-Millán, Iris Y., Bostrom, Mathias P., Parks, Michael L., Padgett, Douglas E., McLawhorn, Alexander S., Antao, Vinicius C., Yates, Adolph J., Springer, Bryan D., Lyman, Stephen L., Singh, Jasvinder A.

“…Total hip replacement (THR)/total knee replacement (TKR) studies do not uniformly measure patient centered domains, pain, and function. We aim to validate…”
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Head-to-Head Comparison of Serial Soluble ST2, Growth Differentiation Factor-15, and Highly-Sensitive Troponin T Measurements in Patients With Chronic Heart Failure by Gaggin, Hanna K., MD, MPH, Szymonifka, Jackie, MA, Bhardwaj, Anju, MD, Belcher, Arianna, BA, De Berardinis, Benedetta, MD, Motiwala, Shweta, MD, Wang, Thomas J., MD, Januzzi, James L., MD

“…Objectives This analysis aimed to perform a head-to-head comparison of 3 of the promising biomarkers of cardiovascular (CV) outcomes in heart failure…”
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Quality of life outcomes in proton and photon treated pediatric brain tumor survivors by Yock, Torunn I, Bhat, Sundeep, Szymonifka, Jackie, Yeap, Beow Y, Delahaye, Jennifer, Donaldson, Sarah S, MacDonald, Shannon M, Pulsifer, Margaret B, Hill, Kristen S, DeLaney, Thomas F, Ebb, David, Huang, Mary, Tarbell, Nancy J, Fisher, Paul Graham, Kuhlthau, Karen A

“…Abstract Background Radiotherapy can impair Health Related Quality of Life (HRQoL) in survivors of childhood brain tumors, but proton radiotherapy (PRT) may…”
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Development and Validation of a Simple-to-Use Nomogram for Predicting 5-, 10-, and 15-Year Survival in Asymptomatic Adults Undergoing Coronary Artery Calcium Scoring by Ó Hartaigh, Bríain, PhD, Gransar, Heidi, MS, Callister, Tracy, MD, Shaw, Leslee J., PhD, Schulman-Marcus, Joshua, MD, Stuijfzand, Wijnand J., MD, Valenti, Valentina, MD, Cho, Iksung, MD, Szymonifka, Jackie, MA, Lin, Fay Y., MD, Berman, Daniel S., MD, Chang, Hyuk-Jae, MD, Min, James K., MD

“…Abstract Objectives The purpose of this study was to develop and validate a simple-to-use nomogram for prediction of 5-, 10-, and 15-year survival among…”
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Spatial environmental factors predict cardiovascular and all-cause mortality: Results of the SPACE study by Hadley, Michael B, Nalini, Mahdi, Adhikari, Samrachana, Szymonifka, Jackie, Etemadi, Arash, Kamangar, Farin, Khoshnia, Masoud, McChane, Tyler, Pourshams, Akram, Poustchi, Hossein, Sepanlou, Sadaf G, Abnet, Christian, Freedman, Neal D, Boffetta, Paolo, Malekzadeh, Reza, Vedanthan, Rajesh

“…Background Environmental exposures account for a growing proportion of global mortality. Large cohort studies are needed to characterize the independent impact…”
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Long-Term Follow-Up of Autotransplantation Trials for Multiple Myeloma: Update of Protocols Conducted by the Intergroupe Francophone du Myelome, Southwest Oncology Group, and University of Arkansas for Medical Sciences by BARLOGIE, Bart, ATTAL, Michel, CROWLEY, John, VAN RHEE, Frits, SZYMONIFKA, Jackie, MOREAU, Philippe, DURIE, Brian G. M, HAROUSSEAU, Jean-Luc

“…The purpose of this study was to update outcomes of autotransplantation trials for myeloma conducted by the Intergroupe Francophone du Myelome (IFM), the…”
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Desmoid Tumor: Analysis of Prognostic Factors and Outcomes in a Surgical Series by Mullen, John T., DeLaney, Thomas F., Kobayashi, Wendy K., Szymonifka, Jackie, Yeap, Beow Y., Chen, Yen-Lin, Rosenberg, Andrew E., Harmon, David C., Choy, Edwin, Yoon, Sam S., Raskin, Kevin A., Petur Nielsen, G., Hornicek, Francis J.

“…Background Desmoid tumors are rare and exhibit a highly unpredictable natural history. We sought to analyze prognostic factors associated with recurrence in a…”
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Total Therapy 3 for multiple myeloma: prognostic implications of cumulative dosing and premature discontinuation of VTD maintenance components, bortezomib, thalidomide, and dexamethasone, relevant to all phases of therapy by van Rhee, Frits, Szymonifka, Jackie, Anaissie, Elias, Nair, Bijay, Waheed, Sarah, Alsayed, Yazan, Petty, Nathan, Shaughnessy, John D., Hoering, Antje, Crowley, John, Barlogie, Bart

“…The impact of cumulative dosing and premature drug discontinuation (PMDD) of bortezomib (V), thalidomide (T), and dexamethasone (D) on overall survival (OS),…”
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Diffuse coronary artery disease among other atherosclerotic plaque characteristics by coronary computed tomography angiography for predicting coronary vessel-specific ischemia by fractional flow reserve by Rizvi, Asim, Hartaigh, Bríain ó, Danad, Ibrahim, Han, Donghee, Lee, Ji Hyun, Gransar, Heidi, Szymonifka, Jackie, Lin, Fay Y, Min, James K

“…Abstract Background and aims Coronary computed tomography angiography (CCTA) permits effective identification of diffuse CAD and atherosclerotic plaque…”
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Mutational analysis and clinical correlation of metastatic colorectal cancer by Russo, Andrea L., Borger, Darrell R., Szymonifka, Jackie, Ryan, David P., Wo, Jennifer Y., Blaszkowsky, Lawrence S., Kwak, Eunice L., Allen, Jill N., Wadlow, Raymond C., Zhu, Andrew X., Murphy, Janet E., Faris, Jason E., Dias‐Santagata, Dora, Haigis, Kevin M., Ellisen, Leif W., Iafrate, Anthony J., Hong, Theodore S.

“…BACKGROUND Early identification of mutations may guide patients with metastatic colorectal cancer toward targeted therapies that may be life prolonging. The…”
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Soluble CD146 Is a Novel Marker of Systemic Congestion in Heart Failure Patients: An Experimental Mechanistic and Transcardiac Clinical Study by Arrigo, Mattia, Truong, Quynh A, Onat, Duygu, Szymonifka, Jackie, Gayat, Etienne, Tolppanen, Heli, Sadoune, Malha, Demmer, Ryan T, Wong, Ka Y, Launay, Jean Marie, Samuel, Jane-Lise, Cohen-Solal, Alain, Januzzi, Jr, James L, Singh, Jagmeet P, Colombo, Paolo C, Mebazaa, Alexandre

“…Soluble CD146 (sCD146), is an endothelial marker with similar diagnostic power as natriuretic peptides in decompensated heart failure (HF). While natriuretic…”
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