Search Results - "Szymanski, Megan"
-
1
Stromal heterogeneity may explain increased incidence of metaplastic breast cancer in women of African descent
Published in Nature communications (14-09-2023)“…The biologic basis of genetic ancestry-dependent variability in disease incidence and outcome is just beginning to be explored. We recently reported enrichment…”
Get full text
Journal Article -
2
Loss of Dnmt3a impairs hematopoietic homeostasis and myeloid cell skewing via the PI3Kinase pathway
Published in JCI insight (08-05-2023)“…Loss-of-function mutations in the DNA methyltransferase 3A (DNMT3A) are seen in a large number of patients with acute myeloid leukemia (AML) with normal…”
Get full text
Journal Article -
3
Fine mapping of the chromosome 10q11-q21 linkage region in Alzheimer's disease cases and controls
Published in Neurogenetics (01-07-2010)“…We have previously reported strong linkage on chromosome 10q in pedigrees transmitting Alzheimer's disease through the mother, overlapping with many…”
Get full text
Journal Article -
4
A reporter Oropouche virus expressing ZsGreen from the M segment enables pathogenesis studies in mice
Published in Journal of virology (17-09-2024)“…Oropouche fever caused by Oropouche virus (OROV) is a significant zoonosis in Central and South America. Despite its public health significance, we lack…”
Get more information
Journal Article -
5
Gene expression reveals overlap between normal aging and Alzheimer's disease genes
Published in Neurobiology of aging (01-12-2011)“…Abstract Alzheimer's disease (AD) is a common cause of dementia with a strong genetic component and risk sharply increasing with age. We performed two parallel…”
Get full text
Journal Article -
6
Abstract P2-26-08: Influence of genetic ancestry on breast stromal cells provides biologic basis for increased incidence of metaplastic breast cancer in women of African descent
Published in Cancer research (Chicago, Ill.) (01-03-2023)“…Abstract The biologic basis of genetic ancestry-dependent variability in disease incidence and outcome is just beginning to be explored. We recently reported…”
Get full text
Journal Article -
7
Neuroglobin and Alzheimer's dementia: Genetic association and gene expression changes
Published in Neurobiology of aging (01-11-2010)“…Abstract We previously reported strong genetic linkage on chromosome 14q to Alzheimer's disease (AD) using the presence of co-morbid hallucinations as a…”
Get full text
Journal Article -
8
Identification and functional studies of regulatory variants responsible for the association of NRG3 with a delusion phenotype in schizophrenia
Published in Molecular neuropsychiatry (01-05-2015)“…We previously reported genetic linkage for Schizophrenia (SZ) (NPL of 4.7) at 10q22 in the Ashkenazi Jewish (AJ) population. In follow up fine mapping we found…”
Get full text
Journal Article -
9
Investigation for Alzheimer's disease susceptibility genes
Published 01-01-2011“…Background Late-onset AD is caused by environmental and genetic factors and interactions between the two. APOE is the only susceptibility gene identified with…”
Get full text
Dissertation