Search Results - "Szyc, Łukasz"
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In vivo two-photon-excited cellular fluorescence of melanin, NAD(P)H, and keratin enables an accurate differential diagnosis of seborrheic keratosis and pigmented cutaneous melanoma
Published in Journal of biomedical optics (01-07-2021)“…Significance: Seborrheic keratoses (SKs) are harmless pigmented skin lesions (PSLs) that may be confused clinically not only with other benign conditions but…”
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2
Aqueous Solvation of Ammonia and Ammonium: Probing Hydrogen Bond Motifs with FT-IR and Soft X‑ray Spectroscopy
Published in Journal of the American Chemical Society (13-09-2017)“…In a multifaceted investigation combining local soft X-ray and vibrational spectroscopic probes with ab initio molecular dynamics simulations, hydrogen-bonding…”
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3
Decelerated Water Dynamics and Vibrational Couplings of Hydrated DNA Mapped by Two-Dimensional Infrared Spectroscopy
Published in The journal of physical chemistry. B (10-11-2011)“…Double-stranded DNA oligomers containing 23 alternating adenine-thymine base pairs are studied at different hydration levels by femtosecond two-dimensional…”
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4
Ultrafast Energy Exchange via Water−Phosphate Interactions in Hydrated DNA
Published in The journal of physical chemistry. B (17-06-2010)“…The ionic phosphate groups in the DNA backbone play a key role for DNA hydration. We study ultrafast vibrational dynamics and local interactions of phosphate…”
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5
Femtosecond Two-Dimensional Infrared Spectroscopy of Adenine-Thymine Base Pairs in DNA Oligomers
Published in The journal of physical chemistry. B (10-02-2011)“…NH and NH2 stretching excitations of adenine-thymine base pairs in double-stranded DNA oligomers are studied by femtosecond two-dimensional (2D) infrared…”
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6
Ultrafast Vibrational Dynamics and Local Interactions of Hydrated DNA
Published in Angewandte Chemie International Edition (10-05-2010)“…Biochemical processes occur mainly in aqueous environments, where interactions with water molecules play a key role for both the structure and function of…”
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7
Diagnostic Performance of a Support Vector Machine for Dermatofluoroscopic Melanoma Recognition: The Results of the Retrospective Clinical Study on 214 Pigmented Skin Lesions
Published in Diagnostics (Basel) (25-08-2019)“…The need for diagnosing malignant melanoma in its earliest stages results in an increasing number of unnecessary excisions. Objective criteria beyond the…”
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8
Development of a handheld fluorescence imaging camera for intraoperative sentinel lymph node mapping
Published in Journal of biomedical optics (01-05-2015)“…We present a compact fluorescence imaging system developed for real-time sentinel lymph node mapping. The device uses two near-infrared wavelengths to record…”
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9
Vibrational dynamics of the water shell of DNA studied by femtosecond two-dimensional infrared spectroscopy
Published in Journal of photochemistry and photobiology. A, Chemistry. (15-04-2012)“…[Display omitted] ► Femtosecond two-dimensional infrared spectroscopy of hydrated DNA. ► Separation of NH stretching excitations of DNA base pairs and OH…”
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10
Resolving the excited state relaxation dynamics of guanosine monomers and hydrogen-bonded homodimers in chloroform solution
Published in Chemical physics (14-11-2018)“…The relaxation pathways of silyl-modified guanosine nucleoside monomers (G) and double-hydrogen-bonded homodimers (GG1) are compared in chloroform solution…”
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11
Dynamics and Couplings of N−H Stretching Excitations of Guanosine−Cytidine Base Pairs in Solution
Published in The journal of physical chemistry. B (12-05-2011)“…N−H stretching vibrations of hydrogen-bonded guanosine−cytidine (G·C) base pairs in chloroform solution are studied with linear and ultrafast nonlinear…”
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12
The Hydrogen-Bonded 2-Pyridone Dimer Model System. 1. Combined NMR and FT-IR Spectroscopy Study
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (29-07-2010)“…2-Pyridone (PD), converting to 2-hydroxypyridine (HP) through a lactam−lactim isomerization mechanism, can form three different cyclic dimers by hydrogen bond…”
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The Hydrogen-Bonded 2-Pyridone Dimer Model System. 2. Femtosecond Mid-Infrared Pump−Probe Study
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (25-11-2010)“…2-Pyridone (PD) tautomerises to 2-hydroxypyridine (HP) in liquid solution, the equilibrium of which is solvent dependent. Dimerization of PD and HP leads to…”
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14
Ultrafast dynamics of N–H and O–H stretching excitations in hydrated DNA oligomers
Published in Chemical physics (23-02-2009)“…DNA oligomers containing 23 alternating adenine–thymine base pairs are studied at different hydration levels by ultrafast two-color pump–probe spectroscopy…”
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15
Note: an environmental cell for transient spectroscopy on solid samples in controlled atmospheres
Published in Review of scientific instruments (01-03-2013)“…A sample cell for performing time-resolved spectroscopy on solid samples within an atmosphere of controlled vapor composition was designed and constructed…”
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16
Ultrafast Vibrational Dynamics of Adenine-Thymine Base Pairs in DNA Oligomers
Published in The journal of physical chemistry. B (11-09-2008)“…N−H stretching excitations of DNA oligomers containing 23 alternating adenine-thymine base pairs are studied in femtosecond two-color pump−probe experiments…”
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17
FTIR-ATR investigations of an α-helix to β-sheet conformational transition in poly( l-lysine)
Published in Journal of molecular liquids (30-06-2008)“…A promising application of the multivariate curve resolution based on alternating least squares (MCR-ALS) method is reported for the analysis of the…”
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18
New Aspects Regarding the Fluorescence Spectra of Melanin and Neuromelanin in Pigmented Human Tissue Concerning Hypoxia
Published in International journal of molecular sciences (01-08-2024)“…Melanin is a crucial pigment in melanomagenesis. Its fluorescence in human tissue is exceedingly weak but can be detected through advanced laser spectroscopy…”
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19
Melanin and Neuromelanin Fluorescence Studies Focusing on Parkinson's Disease and Its Inherent Risk for Melanoma
Published in Cells (Basel, Switzerland) (15-06-2019)“…Parkinson's disease is associated with an increased risk of melanoma (and vice versa). Several hypotheses underline this link, such as pathways affecting both…”
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Ultraschnelle Schwingungsdynamik und lokale Wechselwirkungen in hydratisierter DNA
Published in Angewandte Chemie (10-05-2010)“…Biochemische Prozesse laufen überwiegend in wässriger Umgebung ab. Eine Schlüsselrolle für Struktur und Funktion von Biomolekülen spielt dabei die…”
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