Search Results - "Szpiro, Adam A"

Association between air pollution and coronary artery calcification within six metropolitan areas in the USA (the Multi-Ethnic Study of Atherosclerosis and Air Pollution): a longitudinal cohort study by Kaufman, Joel D, Prof, Adar, Sara D, ScD, Barr, R Graham, MD, Budoff, Matthew, Prof, Burke, Gregory L, Prof, Curl, Cynthia L, PhD, Daviglus, Martha L, Prof, Roux, Ana V Diez, Prof, Gassett, Amanda J, MS, Jacobs, David R, Prof, Kronmal, Richard, Prof, Larson, Timothy V, Prof, Navas-Acien, Ana, MD, Olives, Casey, PhD, Sampson, Paul D, Prof, Sheppard, Lianne, Prof, Siscovick, David S, Prof Emeritus, Stein, James H, Prof, Szpiro, Adam A, PhD, Watson, Karol E, Prof

“…Summary Background Long-term exposure to fine particulate matter less than 2·5 μm in diameter (PM2·5 ) and traffic-related air pollutant concentrations are…”
Get full text

Control for Population Structure and Relatedness for Binary Traits in Genetic Association Studies via Logistic Mixed Models by Chen, Han, Wang, Chaolong, Conomos, Matthew P., Stilp, Adrienne M., Li, Zilin, Sofer, Tamar, Szpiro, Adam A., Chen, Wei, Brehm, John M., Celedón, Juan C., Redline, Susan, Papanicolaou, George J., Thornton, Timothy A., Laurie, Cathy C., Rice, Kenneth, Lin, Xihong

“…Linear mixed models (LMMs) are widely used in genome-wide association studies (GWASs) to account for population structure and relatedness, for both continuous…”
Get full text

Concentrations of criteria pollutants in the contiguous U.S., 1979 - 2015: Role of prediction model parsimony in integrated empirical geographic regression by Kim, Sun-Young, Bechle, Matthew, Hankey, Steve, Sheppard, Lianne, Szpiro, Adam A, Marshall, Julian D

“…National-scale empirical models for air pollution can include hundreds of geographic variables. The impact of model parsimony (i.e., how model performance…”
Get full text

Association Between Long-term Exposure to Ambient Air Pollution and Change in Quantitatively Assessed Emphysema and Lung Function by Wang, Meng, Aaron, Carrie Pistenmaa, Madrigano, Jaime, Hoffman, Eric A, Angelini, Elsa, Yang, Jie, Laine, Andrew, Vetterli, Thomas M, Kinney, Patrick L, Sampson, Paul D, Sheppard, Lianne E, Szpiro, Adam A, Adar, Sara D, Kirwa, Kipruto, Smith, Benjamin, Lederer, David J, Diez-Roux, Ana V, Vedal, Sverre, Kaufman, Joel D, Barr, R. Graham

“…IMPORTANCE: While air pollutants at historical levels have been associated with cardiovascular and respiratory diseases, it is not known whether exposure to…”
Get full text

National PM2.5 and NO2 exposure models for China based on land use regression, satellite measurements, and universal kriging by Xu, Hao, Bechle, Matthew J., Wang, Meng, Szpiro, Adam A., Vedal, Sverre, Bai, Yuqi, Marshall, Julian D.

“…Outdoor air pollution is a major killer worldwide and the fourth largest contributor to the burden of disease in China. China is the most populous country in…”
Get full text

RNAseqCovarImpute: a multiple imputation procedure that outperforms complete case and single imputation differential expression analysis by Baker, Brennan H, Sathyanarayana, Sheela, Szpiro, Adam A, MacDonald, James W, Paquette, Alison G

“…Missing covariate data is a common problem that has not been addressed in observational studies of gene expression. Here, we present a multiple imputation…”
Get full text

A unified spatiotemporal modeling approach for predicting concentrations of multiple air pollutants in the multi-ethnic study of atherosclerosis and air pollution by Keller, Joshua P, Olives, Casey, Kim, Sun-Young, Sheppard, Lianne, Sampson, Paul D, Szpiro, Adam A, Oron, Assaf P, Lindström, Johan, Vedal, Sverre, Kaufman, Joel D

“…Cohort studies of the relationship between air pollution exposure and chronic health effects require predictions of exposure over long periods of time. We…”
Get full text

Combining Land-Use Regression and Chemical Transport Modeling in a Spatiotemporal Geostatistical Model for Ozone and PM2.5 by Wang, Meng, Sampson, Paul D, Hu, Jianlin, Kleeman, Michael, Keller, Joshua P, Olives, Casey, Szpiro, Adam A, Vedal, Sverre, Kaufman, Joel D

“…Assessments of long-term air pollution exposure in population studies have commonly employed land-use regression (LUR) or chemical transport modeling (CTM)…”
Get full text

Publicly available low-cost sensor measurements for PM2.5 exposure modeling: Guidance for monitor deployment and data selection by Bi, Jianzhao, Carmona, Nancy, Blanco, Magali N., Gassett, Amanda J., Seto, Edmund, Szpiro, Adam A., Larson, Timothy V., Sampson, Paul D., Kaufman, Joel D., Sheppard, Lianne

“…•High-resolution PM2.5 models were developed with low-cost PurpleAir measurements.•An independent dataset was used to validate model performance at cohort…”
Get full text

Phthalate mixtures in pregnancy, autistic traits, and adverse childhood behavioral outcomes by Day, Drew B., Collett, Brent R., Barrett, Emily S., Bush, Nicole R., Swan, Shanna H., Nguyen, Ruby H.N., Szpiro, Adam A., Sathyanarayana, Sheela

“…•Maternal gestational phthalate mixtures were associated with child behavior.•Early pregnancy phthalates were associated with autistic traits in both…”
Get full text

A combined cohort analysis of prenatal exposure to phthalate mixtures and childhood asthma by Adgent, Margaret A., Carroll, Kecia N., Hazlehurst, Marnie F., Loftus, Christine T., Szpiro, Adam A., Karr, Catherine J., Barrett, Emily S., LeWinn, Kaja Z., Bush, Nicole R., Tylavsky, Frances A., Kannan, Kurunthachalam, Sathyanarayana, Sheela

“…•The study of prenatal exposure to phthalate mixtures and child asthma is novel.•Phthalates increased odds of asthma in boys and in dyads without maternal…”
Get full text

The cross-sectional and longitudinal association between air pollution and salivary cortisol: Evidence from the Multi-Ethnic Study of Atherosclerosis by Hajat, Anjum, Hazlehurst, Marnie F., Golden, Sherita Hill, Merkin, Sharon Stein, Seeman, Teresa, Szpiro, Adam A., Kaufman, Joel D., Roux, Ana Diez

“…Cortisol, a stress hormone released by the activation of the hypothalamic-pituitary-adrenal (HPA) axis, is critical to the body's adaptive response to…”
Get full text

Exposure to prenatal phthalate mixtures and neurodevelopment in the Conditions Affecting Neurocognitive Development and Learning in Early childhood (CANDLE) study by Loftus, Christine T., Bush, Nicole R., Day, Drew B., Ni, Yu, Tylavsky, Frances A., Karr, Catherine J., Kannan, Kurunthachalam, Barrett, Emily S., Szpiro, Adam A., Sathyanarayana, Sheela, LeWinn, Kaja Z.

“…•This is the first study of phthalate mixtures and child language and cognition.•The study population was a large, diverse longitudinal pregnancy cohort.•We…”
Get full text

Prenatal urinary metabolites of polycyclic aromatic hydrocarbons and toddler cognition, language, and behavior by Wallace, Erin R., Ni, Yu, Loftus, Christine T., Sullivan, Alexis, Masterson, Erin, Szpiro, Adam A., Day, Drew B., Robinson, Morgan, Kannan, Kurunthachalam, Tylavsky, Fran A., Sathyanarayana, Sheela, Bush, Nicole R., LeWinn, Kaja Z., Karr, Catherine J.

“…[Display omitted] •This study examined associations of prenatal PAH and child neurodevelopment.•The study population was a large and diverse longitudinal birth…”
Get full text

Prenatal exposure to polycyclic aromatic hydrocarbons and gestational age at birth by Freije, Sophia L., Enquobahrie, Daniel A., Day, Drew B., Loftus, Christine, Szpiro, Adam A., Karr, Catherine J., Trasande, Leonardo, Kahn, Linda G., Barrett, Emily, Kannan, Kurunthachalam, Bush, Nicole R., LeWinn, Kaja Z., Swan, Shanna, Alex Mason, W., Robinson, Morgan, Sathyanarayana, Sheela

“…[Display omitted] •We examined overall and sex-specific associations of prenatal PAH with GA at birth.•The study population was a large and geographically…”
Get full text

Exposure measurement error in PM2.5 health effects studies: a pooled analysis of eight personal exposure validation studies by Kioumourtzoglou, Marianthi-Anna, Spiegelman, Donna, Szpiro, Adam A, Sheppard, Lianne, Kaufman, Joel D, Yanosky, Jeff D, Williams, Ronald, Laden, Francine, Hong, Biling, Suh, Helen

“…Exposure measurement error is a concern in long-term PM2.5 health studies using ambient concentrations as exposures. We assessed error magnitude by estimating…”
Get full text

Longitudinal Analysis of Long-Term Air Pollution Levels and Blood Pressure: A Cautionary Tale from the Multi-Ethnic Study of Atherosclerosis by Adar, Sara D, Chen, Yeh-Hsin, D'Souza, Jennifer C, O'Neill, Marie S, Szpiro, Adam A, Auchincloss, Amy H, Park, Sung Kyun, Daviglus, Martha L, Diez Roux, Ana V, Kaufman, Joel D

“…Air pollution exposures are hypothesized to impact blood pressure, yet few longitudinal studies exist, their findings are inconsistent, and different…”
Get full text

Maternal exposure to urinary polycyclic aromatic hydrocarbons (PAH) in pregnancy and childhood asthma in a pooled multi-cohort study by Loftus, Christine T., Szpiro, Adam A., Workman, Tomomi, Wallace, Erin R., Hazlehurst, Marnie F., Day, Drew B., Ni, Yu, Carroll, Kecia N., Adgent, Margaret A., Moore, Paul E., Barrett, Emily S, Nguyen, Ruby H.N., Kannan, Kurunthachalam, Robinson, Morgan, Masterson, Erin E., Tylavsky, Frances A., Bush, Nicole R., LeWinn, Kaja Z., Sathyanarayana, Sheela, Karr, Catherine J.

“…Prenatal exposure to polycyclic aromatic hydrocarbons (PAH) may increase risk of pediatric asthma, but existing human studies are limited. We estimated…”
Get full text

Using smartphones to collect time–activity data for long-term personal-level air pollution exposure assessment by Glasgow, Mark L, Rudra, Carole B, Yoo, Eun-Hye, Demirbas, Murat, Merriman, Joel, Nayak, Pramod, Crabtree-Ide, Christina, Szpiro, Adam A, Rudra, Atri, Wactawski-Wende, Jean, Mu, Lina

“…Because of the spatiotemporal variability of people and air pollutants within cities, it is important to account for a person’s movements over time when…”
Get full text

Air pollution and fecundability in a North American preconception cohort study by Wesselink, Amelia K., Hystad, Perry, Kirwa, Kipruto, Kaufman, Joel D., Willis, Mary D., Wang, Tanran R., Szpiro, Adam A., Levy, Jonathan I., Savitz, David A., Rothman, Kenneth J., Hatch, Elizabeth E., Wise, Lauren A.

“…•Residential ambient concentrations of particulate matter, nitrogen dioxide, and ozone were not strongly associated with fecundability, the per cycle…”
Get full text