Search Results - "Szlachtycz, David"

Molecular targeting of the UDP-glucuronosyltransferase enzymes in high-eukaryotic translation initiation factor 4E refractory/relapsed acute myeloid leukemia patients: a randomized phase II trial of vismodegib, ribavirin with or without decitabine by Assouline, Sarit, Gasiorek, Jadwiga, Bergeron, Julie, Lambert, Caroline, Culjkovic-Kraljacic, Biljana, Cocolakis, Eftihia, Zakaria, Chadi, Szlachtycz, David, Yee, Karen, Borden, Katherine L B

“…Drug resistance underpins poor outcomes in many malignancies including refractory and relapsed acute myeloid leukemia (R/R AML). Glucuronidation is a common…”
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PARPi eligibility amongst women with newly diagnosed invasive breast cancer enrolled in the GREAT universal genetic testing study by Wong, Stephanie M., Rezoug, Zoulikha, Totten, Stephanie P, Szlachtycz, David M, Atayan, Adrienne M, Mohler, Kristen, Albert, Sophie, Feng, Leila, Lemieux Anglin, Brianna, Shen, Zhen, Hamel, Nancy, Meti, Nicholas, Esfahani, Khashayar, Anderson, Dawn, Boileau, Jean-Francois, Prakash, Ipshita, Basik, Mark, Meterissian, Sarkis H., Chong, George, Foulkes, William D.

“…531 Background: Poly(ADP-ribose) polymerase inhibitors (PARPi) are approved for the treatment of BRCA-associated metastatic and high-risk early breast cancer…”
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Germline EGFR c.2527G > A (p.V843I) variant and familial lung cancer by Alsaddah, Saba, Papadakis, Andreas I., Wong, Nora, Palma, Laura, Szlachtycz, David, Cruz Marino, Tania, Fiset, Pierre-Olivier, Foulkes, William D

“…•A woman with lung adenocarcinoma was found to carry a rare germline epidermal growth factor receptor (EGFR) variant, known as c.2527G > A, p.V843I.•The…”
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Universal Genetic Testing for Newly Diagnosed Invasive Breast Cancer by Rezoug, Zoulikha, Totten, Stephanie P, Szlachtycz, David, Atayan, Adrienne, Mohler, Kristen, Albert, Sophie, Feng, Leila, Lemieux Anglin, Brianna, Shen, Zhen, Jimenez, Daniel, Hamel, Nancy, Meti, Nicholas, Esfahani, Khashayar, Boileau, Jean-François, Prakash, Ipshita, Basik, Mark, Meterissian, Sarkis, Tremblay, Francine, Fleiszer, David, Anderson, Dawn, Chong, George, Wong, Stephanie M, Foulkes, William D

“…Between 5% and 10% of breast cancer cases are associated with an inherited germline pathogenic or likely pathogenic variant (GPV) in a breast cancer…”
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Germline EGFR c.2527G > A (p.V843I) variant and familial lung cancer by Alsaddah, Saba, Papadakis, Andreas I, Wong, Nora, Palma, Laura, Szlachtycz, David, Cruz Marino, Tania, Fiset, Pierre-Olivier, Foulkes, William D

“…BACKGROUNDSomatic epidermal growth factor receptor (EGFR) pathogenic variants have been identified and are routinely tested in the molecular diagnosis of…”
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