Search Results - "Szilvásy, Nóra"

Prediction of Transporter-Mediated Rosuvastatin Hepatic Uptake Clearance and Drug Interaction in Humans Using Proteomics-Informed REF Approach by Kumar, Vineet, Yin, Mengyue, Ishida, Kazuya, Salphati, Laurent, Hop, Cornelis E C A, Rowbottom, Christopher, Xiao, Guangqing, Lai, Yurong, Mathias, Anita, Chu, Xiaoyan, Humphreys, W Griffith, Liao, Mingxiang, Nerada, Zsuzsanna, Szilvásy, Nóra, Heyward, Scott, Unadkat, Jashvant D

“…Suspended, plated, or sandwich-cultured human hepatocytes are routinely used for in vitro to in vivo extrapolation (IVIVE) of transporter-mediated hepatic…”
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Modulation of Multispecific Transporters by Uncaria tomentosa Extract and Its Major Phytoconstituents by Szilvásy, Nóra, Lajer, Panna, Horváth, Attila, Veres, Katalin, Hohmann, Judit, Schelz, Zsuzsanna, Minorics, Renáta, Zupkó, István, Gáborik, Zsuzsanna, Kis, Emese, Temesszentandrási-Ambrus, Csilla

“…Background/Objectives: One of the major risks associated with the concomitant use of herbal products and therapeutic drugs is herb–drug interactions (HDIs)…”
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P129 - In-vivo transporter-mediated hepatic clearance of rosuvastatin in humans could be better predicted using transporter-expressing cells than hepatocytes by Kumar, Vineet, Ishida, Kazuya, Salphati, Laurent, Hop, Cornelis E.C. A., Rowbottom, Christopher, Xiao, Guangqing, Lai, Yurong, Mathias, Anita, Chu, Xiaoyan, Humphreys, W. Griffith, Liao, Mingxiang, Tóth, Beáta, Szilvásy, Nóra, Heyward, Scott, Unadkat, Jashvant D.

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Applicability of MDR1 Overexpressing Abcb1KO-MDCKII Cell Lines for Investigating In Vitro Species Differences and Brain Penetration Prediction by Sóskuti, Emőke, Szilvásy, Nóra, Temesszentandrási-Ambrus, Csilla, Urbán, Zoltán, Csíkvári, Olivér, Szabó, Zoltán, Kecskeméti, Gábor, Pusztai, Éva, Gáborik, Zsuzsanna

“…Implementing the 3R initiative to reduce animal experiments in brain penetration prediction for CNS-targeting drugs requires more predictive in vitro and in…”
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Investigating cross-species differences of MDR1-mediated drug transport by Temesszentandrasi-Ambrus, Csilla, Heredi-Szabo, Krisztina, Soskuti, Emoke, Szilvasy, Nora, Kis, Emese, Gaborik, Zsuzsanna

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