Search Results - "Szigeti, Krisztina A"
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Diagnostic and prognostic potential of tissue and circulating long non-coding RNAs in colorectal tumors
Published in World journal of gastroenterology : WJG (14-09-2019)“…Long non-coding RNAs (lncRNAs) are members of the non-protein coding RNA family longer than 200 nucleotides. They participate in the regulation of gene and…”
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Global DNA hypomethylation of colorectal tumours detected in tissue and liquid biopsies may be related to decreased methyl-donor content
Published in BMC cancer (02-06-2022)“…Hypomethylation of long interspersed nuclear element 1 (LINE-1) is characteristic of various cancer types, including colorectal cancer (CRC). Malfunction of…”
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Methodological and Biological Factors Influencing Global DNA Methylation Results Measured by LINE-1 Pyrosequencing Assay in Colorectal Tissue and Liquid Biopsy Samples
Published in International journal of molecular sciences (01-10-2022)“…Long interspersed nuclear element 1 (LINE-1) bisulfite pyrosequencing is a widely used technique for genome-wide methylation analyses. We aimed to investigate…”
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A Detailed Overview About the Single-Cell Analyses of Solid Tumors Focusing on Colorectal Cancer
Published in Pathology oncology research (14-07-2022)“…In recent years, the evolution of the molecular biological technical background led to the widespread application of single-cell sequencing, a versatile tool…”
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S-Adenosylmethionine Treatment of Colorectal Cancer Cell Lines Alters DNA Methylation, DNA Repair and Tumor Progression-Related Gene Expression
Published in Cells (Basel, Switzerland) (09-08-2020)“…Global DNA hypomethylation is a characteristic feature of colorectal carcinoma (CRC). The tumor inhibitory effect of S-adenosylmethionine (SAM) methyl donor…”
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Patterns of Somatic Variants in Colorectal Adenoma and Carcinoma Tissue and Matched Plasma Samples from the Hungarian Oncogenome Program
Published in Cancers (31-01-2023)“…Analysis of circulating cell-free DNA (cfDNA) of colorectal adenoma (AD) and cancer (CRC) patients provides a minimally invasive approach that is able to…”
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Folic Acid Treatment Directly Influences the Genetic and Epigenetic Regulation along with the Associated Cellular Maintenance Processes of HT-29 and SW480 Colorectal Cancer Cell Lines
Published in Cancers (03-04-2022)“…Folic acid (FA) is a synthetic form of vitamin B9, generally used as a nutritional supplement and an adjunctive medication in cancer therapy. FA is involved in…”
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Abstract 155: Global DNA hypomethylation can be caused by decreased methyl-donor content in tissue and liquid biopsy samples in colorectal cancer progression
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Backgrounds: Global DNA hypomethylation is characteristic in various cancer types including colorectal cancer. Alterations of DNA methylation related…”
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