Search Results - "Szibor, M."

Phosphodiesterase-4 promotes proliferation and angiogenesis of lung cancer by crosstalk with HIF by Pullamsetti, S S, Banat, G A, Schmall, A, Szibor, M, Pomagruk, D, Hänze, J, Kolosionek, E, Wilhelm, J, Braun, T, Grimminger, F, Seeger, W, Schermuly, R T, Savai, R

“…Lung cancer is the leading cause of cancer death worldwide. Recent data suggest that cyclic nucleotide phosphodiesterases (PDEs) are relevant in various cancer…”
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Mitochondrial ageing by Szibor, M, Holtz, J

“…Mitochondria in largely postmitotic cells (e.g. cardiomyocytes, neurons or skeletal muscle myotubes) have a limited life span of a few weeks. Their replacement…”
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Redox control of mitochondrial functions by Szibor, M, Richter, C, Ghafourifar, P

“…Redox reactions and electron flow through the respiratory chain are the hallmarks of mitochondria. By supporting oxidative phosphorylation and metabolite…”
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Angiotensin-converting enzyme inhibitor therapy prevents upregulation of endothelin-converting enzyme-1 in failing human myocardium by Morawietz, H, Goettsch, W, Szibor, M, Barton, M, Shaw, S, Hakim, K, Zerkowski, H.-R, Holtz, J

“…In this study, we investigated the role of the renin–angiotensin system in expression of the endothelin system in atrial myocardium of patients with congestive…”
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Binding to G-quadruplex RNA activates the mitochondrial GTPase NOA1 by Al-Furoukh, Natalie, Goffart, Steffi, Szibor, Marten, Wanrooij, Sjoerd, Braun, Thomas

“…NOA1 is an evolutionary conserved, nuclear encoded GTPase essential for mitochondrial function and cellular survival. The function of NOA1 for assembly of…”
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S-Nitrosylation of Mitochondrial Caspases by Mannick, Joan B., Schonhoff, Christopher, Papeta, Natalia, Ghafourifar, Pedram, Szibor, Marten, Fang, Kezhong, Gaston, Benjamin

“…Caspase-3 is a cysteine protease located in both the cytoplasm and mitochondrial intermembrane space that is a central effector of many apoptotic pathways. In…”
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Repurposing mitochondria from ATP production to ROS generation drives a pro-inflammatory phenotype in macrophages that depends on succinate oxidation by complex II by Mills, E. L., Kelly, B., Logan, A, Costa, A. S. H., Varma, M., Bryant, C. E., Tourlomousis, P., Däbritz, J. H. M., Gottlieb, E., Latorre, I., Corr, S.C., McManus, G., Ryan, D., Jacobs, H.T., Szibor, M., Xavier, R. J., Braun, T., Frezza, C., Murphy, M. P., O’Neill, L. A.

“…Activated macrophages undergo metabolic reprogramming which drives their pro-inflammatory phenotype, but the mechanistic basis for this remains obscure. Here…”
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Regulation of the endothelin system by shear stress in human endothelial cells by Morawietz, Henning, Talanow, Roland, Szibor, Marten, Rueckschloss, Uwe, Schubert, Andreas, Bartling, Babett, Darmer, Dorothea, Holtz, Juergen

“…In this study, the effect of shear stress on the expression of genes of the human endothelin-1 system was examined. Primary cultures of human umbilical vein…”
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TFAM-dependent and independent dynamics of mtDNA levels in C2C12 myoblasts caused by redox stress by Noack, Heiko, Bednarek, Tobias, Heidler, Juliana, Ladig, Roman, Holtz, Jürgen, Szibor, Marten

“…TFAM is an essential protein factor for the initiation of transcription of the mtDNA. It also functions as a packaging factor, which stabilizes the mtDNA pool…”
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Increased Expression of Endothelin-1 and Inducible Nitric Oxide Synthase Isoform II in Aging Arteries in Vivo: Implications for Atherosclerosis by Goettsch, Winfried, Lattmann, Thomas, Amann, Kerstin, Szibor, Marten, Morawietz, Henning, Münter, Klaus, Müller, Sylvana P., Shaw, Sidney, Barton, Matthias

“…We here report that aging increases expression of endothelin-1 and NO synthases in the vasculature and kidney of normotensive rats in vivo. Expression of…”
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Deloading of the left ventricle by ventricular assist device normalizes increased expression of endothelin ETA receptors but not endothelin-converting enzyme-1 in patients with end-stage heart failure by MORAWIETZ, Henning, SZIBOR, Marten, GOETTSCH, Winfried, BARTLING, Babett, BARTON, Matthias, SHAW, Sidney, KOERFER, Reiner, ZERKOWSKI, Hans-Reinhard, HOLTZ, Juergen

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Serial competitive RT-PCR using multiple standards by Szibor, Marten, Morawietz, Henning

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Deloading of the Left Ventricle by Ventricular Assist Device Normalizes Increased Expression of Endothelin ETA Receptors But Not Endothelin-Converting Enzyme-1 in Patients With End-Stage Heart Failure by Morawietz, H., Szibor, M., Goettsch, W., Bartling, B., Barton, M., Shaw, S., Koerfer, R., Zerkowski, H.-R., Holtz, J.

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Deloading of the left ventricle by ventricular assist device normalizes increased expression of endothelin ET(A) receptors but not endothelin-converting enzyme-1 in patients with end-stage heart failure by Morawietz, H, Szibor, M, Goettsch, W, Bartling, B, Barton, M, Shaw, S, Koerfer, R, Zerkowski, H R, Holtz, J

“…Ventricular assist devices (VAD) are implanted in patients with end-stage heart failure for bridging the time until heart transplantation, resulting in…”
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