Search Results - "Szeto, Ke X."

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results by Margolskee, Alison, Darwich, Adam S., Pepin, Xavier, Aarons, Leon, Galetin, Aleksandra, Rostami-Hodjegan, Amin, Carlert, Sara, Hammarberg, Maria, Hilgendorf, Constanze, Johansson, Pernilla, Karlsson, Eva, Murphy, Dónal, Tannergren, Christer, Thörn, Helena, Yasin, Mohammed, Mazuir, Florent, Nicolas, Olivier, Ramusovic, Sergej, Xu, Christine, Pathak, Shriram M., Korjamo, Timo, Laru, Johanna, Malkki, Jussi, Pappinen, Sari, Tuunainen, Johanna, Dressman, Jennifer, Hansmann, Simone, Kostewicz, Edmund, He, Handan, Heimbach, Tycho, Wu, Fan, Hoft, Carolin, Laplanche, Loic, Pang, Yan, Bolger, Michael B., Huehn, Eva, Lukacova, Viera, Mullin, James M., Szeto, Ke X., Costales, Chester, Lin, Jian, McAllister, Mark, Modi, Sweta, Rotter, Charles, Varma, Manthena, Wong, Mei, Mitra, Amitava, Bevernage, Jan, Biewenga, Jeike, Van Peer, Achiel, Lloyd, Richard, Shardlow, Carole, Langguth, Peter, Mishenzon, Irina, Nguyen, Mai Anh, Brown, Jonathan, Lennernäs, Hans, Abrahamsson, Bertil

“…Orally administered drugs are subject to a number of barriers impacting bioavailability (Foral), causing challenges during drug and formulation development…”
Get full text

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes by Darwich, Adam S., Margolskee, Alison, Pepin, Xavier, Aarons, Leon, Galetin, Aleksandra, Rostami-Hodjegan, Amin, Carlert, Sara, Hammarberg, Maria, Hilgendorf, Constanze, Johansson, Pernilla, Karlsson, Eva, Murphy, Dónal, Tannergren, Christer, Thörn, Helena, Yasin, Mohammed, Mazuir, Florent, Nicolas, Olivier, Ramusovic, Sergej, Xu, Christine, Pathak, Shriram M., Korjamo, Timo, Laru, Johanna, Malkki, Jussi, Pappinen, Sari, Tuunainen, Johanna, Dressman, Jennifer, Hansmann, Simone, Kostewicz, Edmund, He, Handan, Heimbach, Tycho, Wu, Fan, Hoft, Carolin, Pang, Yan, Bolger, Michael B., Huehn, Eva, Lukacova, Viera, Mullin, James M., Szeto, Ke X., Costales, Chester, Lin, Jian, McAllister, Mark, Modi, Sweta, Rotter, Charles, Varma, Manthena, Wong, Mei, Mitra, Amitava, Bevernage, Jan, Biewenga, Jeike, Van Peer, Achiel, Lloyd, Richard, Shardlow, Carole, Langguth, Peter, Mishenzon, Irina, Nguyen, Mai Anh, Brown, Jonathan, Lennernäs, Hans, Abrahamsson, Bertil

“…Three Physiologically Based Pharmacokinetic software packages (GI-Sim, Simcyp® Simulator, and GastroPlus™) were evaluated as part of the Innovative Medicine…”
Get full text