Search Results - "Szeto, Jason"
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Formulation Development of a COVID-19 Recombinant Spike Protein-Based Vaccine
Published in Vaccines (Basel) (23-07-2024)“…The purpose of this study was to develop a formulation for a recombinant prefusion spike protein vaccine against SARS-CoV-2. It was found that the spike…”
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Neutralizing Antibodies Elicited by a Novel Detoxified Pneumolysin Derivative, PlyD1, Provide Protection against Both Pneumococcal Infection and Lung Injury
Published in Infection and Immunity (01-06-2012)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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3
ALIS are Stress-Induced Protein Storage Compartments for Substrates of the Proteasome and Autophagy
Published in Autophagy (01-07-2006)“…Misfolded proteins can be directed into cytoplasmic aggregates such as aggresomes and dendritic cellaggresome-like induced structures (DALIS). DALIS were…”
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Development of an In Vitro Test Method to Replace an Animal-Based Potency Test for Pertactin Antigen in Multivalent Vaccines
Published in Vaccines (Basel) (27-01-2023)“…There is increasing interest to replace animal-based potency assays used routinely to test vaccines, since they are highly variable, are costly, and present…”
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Salmonella-Containing Vacuoles Display Centrifugal Movement Associated with Cell-to-Cell Transfer in Epithelial Cells
Published in Infection and Immunity (01-03-2009)“…Intracellular Salmonella enterica serovar Typhimurium (serovar Typhimurium) occupies a Salmonella-containing vacuole (SCV) where bacterial effector proteins…”
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Role for Myosin II in Regulating Positioning of Salmonella-Containing Vacuoles and Intracellular Replication
Published in Infection and Immunity (01-06-2008)“…Salmonella enterica serovar Typhimurium grows within host cells in a permissive compartment termed the Salmonella-containing vacuole (SCV). These bacteria use…”
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Cutting Edge: Microbial Products Elicit Formation of Dendritic Cell Aggresome-Like Induced Structures in Macrophages
Published in The Journal of immunology (1950) (01-03-2005)“…In response to a maturation stimulus, dendritic cells undergo the formation of ubiquitinated protein aggregates known as dendritic cell aggresome-like induced…”
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Conservation of dynamic localization among MinD and MinE orthologues: oscillation of Neisseria gonorrhoeae proteins in Escherichia coli
Published in Molecular microbiology (01-10-2002)“…Summary Min proteins are involved in the correct placement of division septa in many bacterial species. In Escherichia coli (Ec) cells, these proteins…”
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The N Terminus of MinD Contains Determinants Which Affect Its Dynamic Localization and Enzymatic Activity
Published in Journal of Bacteriology (01-11-2004)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Hydrogen–Deuterium Exchange Epitope Mapping Reveals Distinct Neutralizing Mechanisms for Two Monoclonal Antibodies against Diphtheria Toxin
Published in Biochemistry (Easton) (12-02-2019)“…The diphtheria toxoid (DT) antigen is one of the major components in pediatric and booster combination vaccines and is known to raise a protective humoral…”
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Mutational analysis of Salmonella translocated effector members SifA and SopD2 reveals domains implicated in translocation, subcellular localization and function
Published in Microbiology (Society for General Microbiology) (01-08-2006)“…1 Michael Smith Laboratories and Departments of Biochemistry and Molecular Biology, Microbiology, and Immunology, University of British Columbia, Vancouver,…”
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Microbial Products Elicit Formation of Dendritic Cell Aggresome-Like Induced Structures in Macrophages
Published in The Journal of immunology (1950) (01-03-2005)“…In response to a maturation stimulus, dendritic cells undergo the formation of ubiquitinated protein aggregates known as dendritic cell aggresome-like induced…”
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Gonococcal MinD affects cell division in Neisseria gonorrhoeae and Escherichia coli and exhibits a novel self-interaction
Published in Journal of bacteriology (01-11-2001)“…The Min proteins are involved in determining cell division sites in bacteria and have been studied extensively in rod-shaped bacteria. We have recently shown…”
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The C-terminus of MinE from Neisseria gonorrhoeae acts as a topological specificity factor by modulating MinD activity in bacterial cell division
Published in Research in microbiology (01-05-2006)“…MinE regulates the proper placement of the cytokinetic FtsZ ring at midcell by inducing the pole-to-pole movement of MinCD complexes. While the N-terminus of…”
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Deletion of the cell-division inhibitor MinC results in lysis of Neisseria gonorrhoeae
Published in Microbiology (Society for General Microbiology) (01-01-2001)“…Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada 1 Department of Microbiology,…”
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A conserved polar region in the cell division site determinant MinD is required for responding to MinE-induced oscillation but not for localization within coiled arrays
Published in Research in microbiology (2005)“…A region in the cell division site determinant MinD required for stimulation by MinE and which determines MinD topological specificity along coil-like…”
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Gonococcal MinD Affects Cell Division inNeisseria gonorrhoeae and Escherichia coli and Exhibits a Novel Self-Interaction
Published in Journal of Bacteriology (01-11-2001)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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