Search Results - "Szedlacsek, Stefan E"

Protein tyrosine phosphatases: structure-function relationships by Tabernero, Lydia, Aricescu, A. Radu, Jones, E. Yvonne, Szedlacsek, Stefan E

“…Structural analysis of protein tyrosine phosphatases (PTPs) has expanded considerably in the last several years, producing more than 200 structures in this…”
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Microarray Strategy for Mapping the Substrate Specificity of Protein Tyrosine Phosphatase by Köhn, Maja, Gutierrez-Rodriguez, Marta, Jonkheijm, Pascal, Wetzel, Stefan, Wacker, Ron, Schroeder, Hendrik, Prinz, Heino, Niemeyer, Christof M, Breinbauer, Rolf, Szedlacsek, Stefan E, Waldmann, Herbert

“…Which substrate will it be? Phosphotyrosine peptide microarrays have allowed the substrate specificity to be mapped for two prototypical protein‐tyrosine…”
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Interface analysis of the complex between ERK2 and PTP-SL by Balasu, Mihaela C, Spiridon, Laurentiu N, Miron, Simona, Craescu, Constantin T, Scheidig, Axel J, Petrescu, Andrei-Jose, Szedlacsek, Stefan E

“…The activity of ERK2, an essential component of MAP-kinase pathway, is under the strict control of various effector proteins. Despite numerous efforts, no…”
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Functional, fractal nonlinear response with application to rate processes with memory, allometry, and population genetics by Vlad, Marcel O, Morán, Federico, Popa, Vlad T, Szedlacsek, Stefan E, Ross, John

“…We give a functional generalization of fractal scaling laws applied to response problems as well as to probability distributions. We consider excitations and…”
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WDR1 is a novel EYA3 substrate and its dephosphorylation induces modifications of the cellular actin cytoskeleton by Mentel, Mihaela, Ionescu, Aura E., Puscalau-Girtu, Ioana, Helm, Martin S., Badea, Rodica A., Rizzoli, Silvio O., Szedlacsek, Stefan E.

“…Eyes absent (EYA) proteins are unusual proteins combining in a single polypeptide chain transactivation, threonine phosphatase, and tyrosine phosphatase…”
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Author Correction: WDR1 is a novel EYA3 substrate and its dephosphorylation induces modifications of the cellular actin cytoskeleton by Mentel, Mihaela, Ionescu, Aura E., Puscalau-Girtu, Ioana, Helm, Martin S., Badea, Rodica A., Rizzoli, Silvio O., Szedlacsek, Stefan E.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Fisher's Theorems for Multivariable, Time- and Space-Dependent Systems, with Applications in Population Genetics and Chemical Kinetics by Vlad, Marcel O., Szedlacsek, Stefan E., Pourmand, Nader, Cavalli-Sforza, L. Luca, Oefner, Peter, Ross, John

“…We study different physical, chemical, or biological processes involving replication, transformation, and disappearance processes, as well as transport…”
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Analysis of EYA3 Phosphorylation by Src Kinase Identifies Residues Involved in Cell Proliferation by Ionescu, Aura E, Mentel, Mihaela, Munteanu, Cristian V A, Sima, Livia E, Martin, Eliza C, Necula-Petrareanu, Georgiana, Szedlacsek, Stefan E

“…Eyes absent (EYA) are non-thiol-based protein tyrosine phosphatases (PTPs) that also have transcriptional co-activator functions. Their PTP activity is…”
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Phosphoketolases from Lactococcus lactis, Leuconostoc mesenteroides and Pseudomonas aeruginosa: dissimilar sequences, similar substrates but distinct enzymatic characteristics by Petrareanu, Georgiana, Balasu, Mihaela C, Vacaru, Andrei M, Munteanu, Cristian V. A, Ionescu, Aura E, Matei, Iulia, Szedlacsek, Stefan E

“…Phosphoketolases (PKs) are large thiamine pyrophosphate (TPP)-dependent enzymes playing key roles in a number of essential pathways of carbohydrate metabolism…”
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Expression, Purification, and Kinetic Analysis of PTP Domains by Mentel, Mihaela, Badea, Rodica A, Necula-Petrareanu, Georgiana, Mallikarjuna, Sujay T, Ionescu, Aura E, Szedlacsek, Stefan E

“…Protein tyrosine phosphatases (PTP) are a large group of enzymes which work together with protein tyrosine kinases to control the tyrosine phosphorylation of…”
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Identification and Specificity Profiling of Protein Prenyltransferase Inhibitors Using New Fluorescent Phosphoisoprenoids by Dursina, Beatrice, Reents, Reinhard, Delon, Christine, Wu, Yaowen, Kulharia, Mahesh, Thutewohl, Michael, Veligodsky, Alexei, Kalinin, Alexandr, Evstifeev, Vladimir, Ciobanu, Doina, Szedlacsek, Stefan E, Waldmann, Herbert, Goody, Roger S, Alexandrov, Kirill

“…Posttranslational modification of proteins with farnesyl and geranylgeranyl isoprenoids is a widespread phenomenon in eukaryotic organisms. Isoprenylation is…”
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The MAM (Meprin/A5-protein/PTPmu) Domain Is a Homophilic Binding Site Promoting the Lateral Dimerization of Receptor-like Protein-tyrosine Phosphatase μ by Cismasiu, Valeriu B., Denes, Stefan A., Reiländer, Helmut, Michel, Hartmut, Szedlacsek, Stefan E.

“…The MAM (meprin/A5-protein/PTPmu) domain is present in numerous proteins with diverse functions. PTPμ belongs to the MAM-containing subclass of…”
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Analysis of molecular determinants of PRL‐3 by Pascaru, Mihaela, Tanase, Carmen, Vacaru, Andrei M., Boeti, Patricia, Neagu, Elena, Popescu, Irinel, Szedlacsek, Stefan E.

“…In order to analyse whether a C‐terminal polybasic sequence represents a nuclear localization signal (NLS) we obtained several truncated and mutant forms of…”
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Kinetics of slow and tight-binding inhibitors by Szedlacsek, S E, Duggleby, R G

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Preliminary X-ray crystallographic analysis of the d-xylulose 5-phosphate phosphoketolase from Lactococcus lactis by Petrareanu, Georgiana, Balasu, Mihaela C., Zander, Ulrich, Scheidig, Axel J., Szedlacsek, Stefan E.

“…Phosphoketolases are thiamine diphosphate‐dependent enzymes which play a central role in the pentose‐phosphate pathway of heterofermentative lactic acid…”
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Esterification of Oxysterols by Human Plasma Lecithin-Cholesterol Acyltransferase by Szedlacsek, Stefan E., Wasowicz, Erwin, Hulea, Stefan A., Nishida, Hiro I., Kummerow, Fred A., Nishida, Toshiro

“…In the present study, lecithin-cholesterol acyltransferase (LCAT) catalyzed esterification of oxysterols was investigated by using discoidal bilayer particles…”
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The MAM (Meprin/A5-protein/PTPmu) Domain Is a Homophilic Binding Site Promoting the Lateral Dimerization of Receptor-like Protein-tyrosine Phosphatase Πby Valeriu B. Cismasiu, Stefan A. Denes, Helmut Reiländer, Hartmut Michel, Stefan E. Szedlacsek

“…The MAM ( m eprin/ A 5-protein/PTP m u) domain is present in numerous proteins with diverse functions. PTPμ belongs to the MAM-containing subclass of…”
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Crystal structure of PTP-SL/PTPBR7 catalytic domain: implications for map kinase regulation 1 1Edited by D. Rees by Szedlacsek, Stefan E, Aricescu, Alexandru R, Fulga, Tudor A, Renault, Louis, Scheidig, Axel J

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Crystal structure of PTP-SL/PTPBR7 catalytic domain: implications for MAP kinase regulation by Szedlacsek, S E, Aricescu, A R, Fulga, T A, Renault, L, Scheidig, A J

“…Protein tyrosine phosphatases PTP-SL and PTPBR7 are isoforms belonging to cytosolic membrane-associated and to receptor-like PTPs (RPTPs), respectively. They…”
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Intramolecular Interactions in Protein Tyrosine Phosphatase RPTPμ: Kinetic Evidence by Aricescu, Alexandru R., Fulga, Tudor A., Cismasiu, Valeriu, Goody, Roger S., Szedlacsek, Stefan E.

“…The receptor-like protein tyrosine phosphatase RPTPμ contains three intracellular domains: the juxtamembrane (JM) and two phosphatase domains (D1 and D2). D1…”
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