Search Results - "Sze, Siu Kwan"

Vimentin protects differentiating stem cells from stress by Pattabiraman, Sundararaghavan, Azad, Gajendra Kumar, Amen, Triana, Brielle, Shlomi, Park, Jung Eun, Sze, Siu Kwan, Meshorer, Eran, Kaganovich, Daniel

“…Vimentin is one of the first cytoplasmic intermediate filaments to be expressed in mammalian cells during embryogenesis, but its role in cellular fitness has…”
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PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1–Parkin-mediated mitophagy by Wang, Liming, Cho, Yik-Lam, Tang, Yancheng, Wang, Jigang, Park, Jung-Eun, Wu, Yajun, Wang, Chunxin, Tong, Yan, Chawla, Ritu, Zhang, Jianbin, Shi, Yin, Deng, Shuo, Lu, Guang, Wu, Yihua, Tan, Hayden Weng-Siong, Pawijit, Pornteera, Lim, Grace Gui-Yin, Chan, Hui-Ying, Zhang, Jingzi, Fang, Lei, Yu, Hanry, Liou, Yih-Cherng, Karthik, Mallilankaraman, Bay, Boon-Huat, Lim, Kah-Leong, Sze, Siu-Kwan, Yap, Celestial T., Shen, Han-Ming

“…Mitophagy is an important type of selective autophagy for specific elimination of damaged mitochondria. PTEN-induced putative kinase protein 1…”
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Materials Stiffness‐Dependent Redox Metabolic Reprogramming of Mesenchymal Stem Cells for Secretome‐Based Therapeutic Angiogenesis by Yang, Haibo, Cheam, Nicole Mein Ji, Cao, Huan, Lee, Melissa Kao Hui, Sze, Siu Kwan, Tan, Nguan Soon, Tay, Chor Yong

“…Cellular redox metabolism has emerged as a key tenet in stem cell biology that can profoundly influence the paracrine activity and therapeutic efficacy of…”
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Sall4 Interacts with Nanog and Co-occupies Nanog Genomic Sites in Embryonic Stem Cells by Wu, Qiang, Chen, Xi, Zhang, Jinqiu, Loh, Yuin-Han, Low, Teck-Yew, Zhang, Weiwei, Zhang, Wensheng, Sze, Siu-Kwan, Lim, Bing, Ng, Huck-Hui

“…Embryonic stem (ES) cells are pluripotent cells with self-renewing property. Nanog is a homeobox transcription factor required to maintain ES cells in a…”
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Activated brown adipose tissue releases exosomes containing mitochondrial methylene tetrahydrofolate dehydrogenase (NADP dependent) 1-like protein (MTHFD1L) by Leow, Melvin Khee-Shing, Rengaraj, Anantharaj, Narasimhan, Kothandaraman, Verma, Sanjay K, Yaligar, Jadegoud, Thu, Giang Le Thi, Sun, Lijuan, Goh, Hui Jen, Govindharajulu, Priya, Sadananthan, Suresh Anand, Michael, Navin, Meng, Wei, Gallart-Palau, Xavier, Sun, Lei, Karnani, Neerja, Sze, Newman Siu Kwan, Velan, S Sendhil

“…Brown adipose tissue (BAT) is a promising weapon to combat obesity and metabolic disease. BAT is thermogenic and consumes substantial amounts of glucose and…”
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The protein kinase CK2 catalytic domain from Plasmodium falciparum: crystal structure, tyrosine kinase activity and inhibition by Ruiz-Carrillo, David, Lin, Jianqing, El Sahili, Abbas, Wei, Meng, Sze, Siu Kwan, Cheung, Peter C. F., Doerig, Christian, Lescar, Julien

“…Malaria causes every year over half-a-million deaths. The emergence of parasites resistant to available treatments makes the identification of new targets and…”
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Differential Association of Chromatin Proteins Identifies BAF60a/SMARCD1 as a Regulator of Embryonic Stem Cell Differentiation by Alajem, Adi, Biran, Alva, Harikumar, Arigela, Sailaja, Badi Sri, Aaronson, Yair, Livyatan, Ilana, Nissim-Rafinia, Malka, Sommer, Andreia Gianotti, Mostoslavsky, Gustavo, Gerbasi, Vincent R., Golden, Daniel E., Datta, Arnab, Sze, Siu Kwan, Meshorer, Eran

“…Embryonic stem cells (ESCs) possess a distinct chromatin conformation maintained by specialized chromatin proteins. To identify chromatin regulators in ESCs,…”
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Extracellular Vesicle Proteome of Breast Cancer Patients with and Without Cognitive Impairment Following Anthracycline-based Chemotherapy: An Exploratory Study by Koh, Yong Qin, Ng, Ding Quan, Ng, Chiu Chin, Boey, Adrian, Wei, Meng, Sze, Siu Kwan, Ho, Han Kiat, Acharya, Munjal, Limoli, Charles L, Chan, Alexandre

“…Cognitive impairment due to cancer and its therapy is a major concern among cancer patients and survivors. Extracellular vesicle (EVs) composition altered by…”
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Identification of Novel Functional Differences in Monocyte Subsets Using Proteomic and Transcriptomic Methods by Zhao, Changqing, Zhang, Huoming, Wong, Wing-Cheong, Sem, Xiaohui, Han, Hao, Ong, Siew-Min, Tan, Yann-Chong, Yeap, Wei-Hseun, Gan, Chee-Sian, Ng, Kok-Quan, Koh, Mickey Boon-Chai, Kourilsky, Philippe, Sze, Siu-Kwan, Wong, Siew-Cheng

“…Human blood monocytes can be broadly divided into two distinct subsets: CD14+CD16− and CD14+/lowCD16+ subsets. Perturbation in their proportions in the blood…”
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HERC5 Is an IFN-Induced HECT-Type E3 Protein Ligase That Mediates Type I IFN-Induced ISGylation of Protein Targets by Wong, Joyce Jing Yi, Pung, Yuh Fen, Sze, Newman Siu-Kwan, Chin, Keh-Chuang

“…Type I IFNs induce the expression of IFN-stimulated gene 15 (ISG15) and its conjugation to cellular targets. ISGylation is a multistep process involving…”
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Hypoxia-induced tumor exosomes promote M2-like macrophage polarization of infiltrating myeloid cells and microRNA-mediated metabolic shift by Park, Jung Eun, Dutta, Bamaprasad, Tse, Shun Wilford, Gupta, Nikhil, Tan, Chee Fan, Low, Jee Keem, Yeoh, Kheng Wei, Kon, Oi Lian, Tam, James P., Sze, Siu Kwan

“…Developing tumors rapidly outgrow their oxygen supply and are subject to hypoxia, which stimulates hypersecretion of tumor-derived exosomes that promote…”
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High myeloid-related protein: 8/14 levels are related to an increased risk of cardiovascular events after carotid endarterectomy by Ionita, Mihaela G, Catanzariti, Louise M, Bots, Michiel L, de Vries, Jean-Paul P M, Moll, Frans L, Kwan Sze, Siu, Sze Kwan, Siu, Pasterkamp, Gerard, de Kleijn, Dominique P V

“…Myeloid-related protein (Mrp) 8/14 complex is the functional relevant form of Mrp-8 and Mrp-14. Mrp-8/14 complex is actively formed in the cytoplasm of…”
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Quantitative profiling brain proteomes revealed mitochondrial dysfunction in Alzheimer's disease by Adav, Sunil S, Park, Jung Eun, Sze, Siu Kwan

“…Mitochondrial dysfunction is a key feature in both aging and neurodegenerative diseases including Alzheimer's disease (AD), but the molecular signature that…”
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Detection, Evaluation and Minimization of Nonenzymatic Deamidation in Proteomic Sample Preparation by Hao, Piliang, Ren, Yan, Alpert, Andrew J., Sze, Siu Kwan

“…Identification of deamidated sites in proteins is commonly used for assignment of N-glycosylation sites. It is also important for assessing the role of…”
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Clinical implications of extracellular vesicles in neurodegenerative diseases by Vinaiphat, Arada, Sze, Siu Kwan

“…: Extracellular vesicles (EVs) released by neural cells play a crucial role in intracellular communication in both physiological and pathological states…”
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Proteomic Profiling of the Secretome of Trichoderma reesei by Ngan, So Fong Cam, Sze, Siu Kwan

“…Trichoderma reesei (T. reesei) is the workhorse for the production of industrial cellulolytic enzyme cocktails for cellulose hydrolysis. However, the current…”
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Enrichment of extracellular vesicles from tissues of the central nervous system by PROSPR by Gallart-Palau, Xavier, Serra, Aida, Sze, Siu Kwan

“…Extracellular vesicles (EVs) act as key mediators of intercellular communication and are secreted and taken up by all cell types in the central nervous system…”
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Alzheimer's disease progression characterized by alterations in the molecular profiles and biogenesis of brain extracellular vesicles by Gallart-Palau, Xavier, Guo, Xue, Serra, Aida, Sze, Siu Kwan

“…The contributions of brain intercellular communication mechanisms, specifically extracellular vesicles (EV), to the progression of Alzheimer's disease (AD)…”
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Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation targets of EGF signaling and Iressa in human cancer cells by Chen, Yunhao, Low, Teck-Yew, Choong, Lee-Yee, Ray, Rajarshi Sankar, Tan, Yee-Ling, Toy, Weiyi, Lin, Qingsong, Ang, Boon Keong, Wong, Chee Hong, Lim, Simin, Li, Bin, Hew, Choy-Leong, Sze, Newman Siu-Kwan, Druker, Brian J., Lim, Yoon-Pin

“…With the completion of the human genome project, analysis of enriched phosphotyrosyl proteins from epidermal growth factor (EGF)‐induced phosphotyrosine…”
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Recent advances in mass spectrometric analysis of protein deamidation by Hao, Piliang, Adav, Sunil S., Gallart‐Palau, Xavier, Sze, Siu Kwan

“…Protein deamidation has been proposed to represent a “molecular clock” that progressively disrupts protein structure and function in human degenerative…”
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