Search Results - "Szczurkowska, Joanna"
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Simultaneous two-photon imaging of intracellular chloride concentration and pH in mouse pyramidal neurons in vivo
Published in Proceedings of the National Academy of Sciences - PNAS (10-10-2017)“…Intracellular chloride ([Cl⁻]i) and pH(pHi) are fundamental regulators of neuronal excitability. They exert wide-ranging effects on synaptic signaling and…”
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Repositioning of Somatic Golgi Apparatus Is Essential for the Dendritic Establishment of Adult-Born Hippocampal Neurons
Published in The Journal of neuroscience (17-01-2018)“…New dentate granule cells (DGCs) are continuously generated, and integrate into the preexisting hippocampal network in the adult brain. How an adult-born…”
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Non-hyperpolarizing GABAB receptor activation regulates neuronal migration and neurite growth and specification by cAMP/LKB1
Published in Nature communications (30-04-2013)“…γ-Aminobutyric acid is the principal inhibitory neurotransmitter in adults, acting through ionotropic chloride-permeable GABA A receptors (GABA A Rs), and…”
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A Cell Surface Biotinylation Assay to Reveal Membrane-associated Neuronal Cues: Negr1 Regulates Dendritic Arborization
Published in Molecular & cellular proteomics (01-03-2014)“…A complex and still not comprehensively resolved panel of transmembrane proteins regulates the outgrowth and the subsequent morphological and functional…”
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Synapsin III acts downstream of semaphorin 3A/CDK5 signaling to regulate radial migration and orientation of pyramidal neurons in vivo
Published in Cell reports (Cambridge) (14-04-2015)“…Synapsin III (SynIII) is a phosphoprotein that is highly expressed at early stages of neuronal development. Whereas in vitro evidence suggests a role for…”
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Targeted in vivo genetic manipulation of the mouse or rat brain by in utero electroporation with a triple-electrode probe
Published in Nature protocols (01-03-2016)“…This protocol extension describes how to electroporate rodent neuronal progenitors in utero with greater accuracy by using triple-electrode probes. This…”
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Directed mechanisms for apical dendrite development during neuronal polarization
Published in Developmental biology (01-10-2022)“…The development of the dendrite and the axon during neuronal polarization underlies the directed flow of information in the brain. Seminal studies on axon…”
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NEGR1 and FGFR2 cooperatively regulate cortical development and core behaviours related to autism disorders in mice
Published in Brain (London, England : 1878) (01-09-2018)“…See Contreras and Hippenmeyer (doi:10.1093/brain/awy218) for a scientific commentary on this article. Autism spectrum disorders (ASDs) are complex conditions…”
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KCC2 Regulates Dendritic Spine Formation in a Brain-Region Specific and BDNF Dependent Manner
Published in Cerebral cortex (New York, N.Y. 1991) (01-11-2018)“…Abstract KCC2 is the major chloride extruder in neurons. The spatiotemporal regulation of KCC2 expression orchestrates the developmental shift towards…”
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Semaphorin3A/PlexinA3 association with the Scribble scaffold for cGMP increase is required for apical dendrite development
Published in Cell reports (Cambridge) (15-03-2022)“…The development of the apical dendrite from the leading process of the bipolar pyramidal neuron might be directed by spatially organized extrinsic cues acting…”
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A Localized Scaffold for cGMP Increase Is Required for Apical Dendrite Development
Published in Cell reports (Cambridge) (14-04-2020)“…Studies in cultured neurons have established that axon specification instructs neuronal polarization and is necessary for dendrite development. However,…”
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Synchronous Bioimaging of Intracellular pH and Chloride Based on LSS Fluorescent Protein
Published in ACS chemical biology (17-06-2016)“…Ion homeostasis regulates critical physiological processes in the living cell. Intracellular chloride concentration not only contributes in setting the…”
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The role of Negr1 in cortical development via NCAM-FGFR2 signaling
Published in SpringerPlus (12-06-2015)Get full text
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Increased performance in genetic manipulation by modeling the dielectric properties of the rodent brain
Published in 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) (2013)“…Genetic approaches to control DNA expression in different brain areas have provided an excellent system to characterize gene function in health and disease of…”
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