Search Results - "Szczerba, Barbara M."
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E-cadherin is required for metastasis in multiple models of breast cancer
Published in Nature (London) (01-09-2019)“…Metastasis is the major driver of death in patients with cancer. Invasion of surrounding tissues and metastasis have been proposed to initiate following loss…”
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Circulating Tumor Cell-Neutrophil Tango along the Metastatic Process
Published in Cancer research (Chicago, Ill.) (15-12-2019)“…The crosstalk between cancer cells and the immune system is crucial for disease progression and its therapeutic targeting is providing exciting results, in…”
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Interaction between innate immunity and Ro52-induced antibody causes Sjögren's syndrome-like disorder in mice
Published in Annals of the rheumatic diseases (01-03-2016)“…Autoantibodies reactive with Ro52 are often found in sera of patients with Sjögren's syndrome (SS). This study was undertaken to investigate the role of…”
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T cell epitope mimicry between Sjögren's syndrome Antigen A (SSA)/Ro60 and oral, gut, skin and vaginal bacteria
Published in Clinical immunology (Orlando, Fla.) (01-05-2014)“…Abstract This study was undertaken to test the hypothesis that Sjogren's syndrome Antigen A (SSA)/Ro60-reactive T cells are activated by peptides originating…”
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Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage
Published in Cell reports (Cambridge) (03-08-2021)“…We lack a holistic understanding of the genetic programs orchestrating embryonic colon morphogenesis and governing damage response in the adult. A window into…”
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An In Vivo CRISPR Screen Identifies Stepwise Genetic Dependencies of Metastatic Progression
Published in Cancer research (Chicago, Ill.) (15-02-2022)“…Blood-borne metastasis of breast cancer involves a series of tightly regulated sequential steps, including the growth of a primary tumor lesion, intravasation…”
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Micromanipulation of Circulating Tumor Cells for Downstream Molecular Analysis and Metastatic Potential Assessment
Published in Journal of visualized experiments (14-05-2019)“…Blood-borne metastasis accounts for most cancer-related deaths and involves circulating tumor cells (CTCs) that are successful in establishing new tumors at…”
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