Search Results - "Szczepanska, Joanna"

Pro- and Antioxidant Effects of Vitamin C in Cancer in correspondence to Its Dietary and Pharmacological Concentrations by Pawlowska, Elzbieta, Blasiak, Janusz, Szczepanska, Joanna

“…Vitamin C is an antioxidant that may scavenge reactive oxygen species preventing DNA damage and other effects important in cancer transformation. Dietary…”
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Interplay between Autophagy and the Ubiquitin-Proteasome System and Its Role in the Pathogenesis of Age-Related Macular Degeneration by Blasiak, Janusz, Pawlowska, Elzbieta, Szczepanska, Joanna, Kaarniranta, Kai

“…Age-related macular degeneration (AMD) is a complex eye disease with many pathogenesis factors, including defective cellular waste management in retinal…”
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Role of Mitochondrial DNA Damage in ROS-Mediated Pathogenesis of Age-Related Macular Degeneration (AMD) by Kaarniranta, Kai, Pawlowska, Elzbieta, Szczepanska, Joanna, Jablkowska, Aleksandra, Blasiak, Janusz

“…Age-related macular degeneration (AMD) is a complex eye disease that affects millions of people worldwide and is the main reason for legal blindness and vision…”
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An Interplay between Senescence, Apoptosis and Autophagy in Glioblastoma Multiforme-Role in Pathogenesis and Therapeutic Perspective by Pawlowska, Elzbieta, Szczepanska, Joanna, Szatkowska, Magdalena, Blasiak, Janusz

“…Autophagy, cellular senescence, programmed cell death and necrosis are key responses of a cell facing a stress. These effects are partly interconnected, but…”
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Dietary Polyphenols in Age-Related Macular Degeneration: Protection against Oxidative Stress and Beyond by Kaarniranta, Kai, Koskela, Ali, Szczepanska, Joanna, Pawlowska, Elzbieta, Blasiak, Janusz

“…Age-related macular degeneration (AMD) is a multifactorial disease of the retina featured by degeneration and loss of photoreceptors and retinal pigment…”
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The Long Noncoding RNA HOTAIR in Breast Cancer: Does Autophagy Play a Role? by Pawłowska, Elżbieta, Szczepanska, Joanna, Blasiak, Janusz

“…HOTAIR (HOX transcript antisense RNA) plays a critical role in chromatin dynamics through the interaction with histone modifiers resulting in transcriptional…”
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The Aging Stress Response and Its Implication for AMD Pathogenesis by Blasiak, Janusz, Pawlowska, Elzbieta, Sobczuk, Anna, Szczepanska, Joanna, Kaarniranta, Kai

“…Aging induces several stress response pathways to counterbalance detrimental changes associated with this process. These pathways include nutrient signaling,…”
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Kynurenine Pathway of Tryptophan Metabolism in Migraine and Functional Gastrointestinal Disorders by Fila, Michal, Chojnacki, Jan, Pawlowska, Elzbieta, Szczepanska, Joanna, Chojnacki, Cezary, Blasiak, Janusz

“…Migraine, the leading cause of disability in the population aged below 50, is associated with functional gastrointestinal (GI) disorders (FGIDs) such as…”
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Potential of Telomerase in Age-Related Macular Degeneration—Involvement of Senescence, DNA Damage Response and Autophagy and a Key Role of PGC-1α by Blasiak, Janusz, Szczepanska, Joanna, Fila, Michal, Pawlowska, Elzbieta, Kaarniranta, Kai

“…Age-related macular degeneration (AMD), the main cause of vision loss in the elderly, is associated with oxidation in the retina cells promoting telomere…”
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Zinc and Autophagy in Age-Related Macular Degeneration by Blasiak, Janusz, Pawlowska, Elzbieta, Chojnacki, Jan, Szczepanska, Joanna, Chojnacki, Cezary, Kaarniranta, Kai

“…Zinc supplementation is reported to slow down the progression of age-related macular degeneration (AMD), but there is no general consensus on the beneficiary…”
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DNA2-An Important Player in DNA Damage Response or Just Another DNA Maintenance Protein? by Pawłowska, Elzbieta, Szczepanska, Joanna, Blasiak, Janusz

“…The human DNA2 (DNA replication helicase/nuclease 2) protein is expressed in both the nucleus and mitochondria, where it displays ATPase-dependent nuclease and…”
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A New Generation of Gene Therapies as the Future of Wet AMD Treatment by Blasiak, Janusz, Pawlowska, Elzbieta, Ciupińska, Justyna, Derwich, Marcin, Szczepanska, Joanna, Kaarniranta, Kai

“…Age-related macular degeneration (AMD) is an eye disease and the most common cause of vision loss in the Western World. In its advanced stage, AMD occurs in…”
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NF-κB-Mediated Inflammation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage. Does Autophagy Play a Role? by Pawlowska, Elzbieta, Szczepanska, Joanna, Wisniewski, Karol, Tokarz, Paulina, Jaskólski, Dariusz J, Blasiak, Janusz

“…The rupture of saccular intracranial aneurysms (IA) is the commonest cause of non-traumatic subarachnoid hemorrhage (SAH)-the most serious form of stroke with…”
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Nutrition in Cancer Therapy in the Elderly-An Epigenetic Connection? by Blasiak, Janusz, Chojnacki, Jan, Pawlowska, Elzbieta, Szczepanska, Joanna, Chojnacki, Cezary

“…The continuous increase in life expectancy results in a steady increase of cancer risk, which consequently increases the population of older adults with…”
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Epigallocatechin-3-Gallate, an Active Green Tea Component to Support Anti-VEGFA Therapy in Wet Age-Related Macular Degeneration by Blasiak, Janusz, Chojnacki, Jan, Szczepanska, Joanna, Fila, Michal, Chojnacki, Cezary, Kaarniranta, Kai, Pawlowska, Elzbieta

“…Age-related macular degeneration (AMD) is a largely incurable disease and an emerging problem in aging societies. It occurs in two forms, dry and wet…”
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Vitamin D in Triple-Negative and BRCA1-Deficient Breast Cancer-Implications for Pathogenesis and Therapy by Blasiak, Janusz, Pawlowska, Elzbieta, Chojnacki, Jan, Szczepanska, Joanna, Fila, Michal, Chojnacki, Cezary

“…Several studies show that triple-negative breast cancer (TNBC) patients have the lowest vitamin D concentration among all breast cancer types, suggesting that…”
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mRNA Trafficking in the Nervous System: A Key Mechanism of the Involvement of Activity-Regulated Cytoskeleton-Associated Protein (Arc) in Synaptic Plasticity by Fila, Michal, Diaz, Laura, Szczepanska, Joanna, Pawlowska, Elzbieta, Blasiak, Janusz

“…Synaptic activity mediates information storage and memory consolidation in the brain and requires a fast de novo synthesis of mRNAs in the nucleus and proteins…”
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Potential of Long Non-Coding RNAs in Age-Related Macular Degeneration by Blasiak, Janusz, Hyttinen, Juha M T, Szczepanska, Joanna, Pawlowska, Elzbieta, Kaarniranta, Kai

“…Age-related macular degeneration (AMD) is the leading cause of visual impairment in the aging population with poorly known pathogenesis and lack of effective…”
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Genotoxicity and cytotoxicity of 2-hydroxyethyl methacrylate by Pawlowska, Elzbieta, Poplawski, Tomasz, Ksiazek, Dominika, Szczepanska, Joanna, Blasiak, Janusz

“…Resin-based methacrylate materials are widely used in restorative dentistry. They are viscous substances that are converted into solid material via…”
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Dexamethasone and 1,25-dihydroxyvitamin D3 reduce oxidative stress-related DNA damage in differentiating osteoblasts by Pawlowska, Elzbieta, Wysokiński, Daniel, Tokarz, Paulina, Piastowska-Ciesielska, Agnieszka, Szczepanska, Joanna, Blasiak, Janusz

“…The process of osteoblast differentiation is regulated by several factors, including RUNX2. Recent reports suggest an involvement of RUNX2 in DNA damage…”
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