Search Results - "Szasz, Taylor P."
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Alveolar macrophage development in mice requires L-plastin for cellular localization in alveoli
Published in Blood (15-12-2016)“…Alveolar macrophages are lung-resident sentinel cells that develop perinatally and protect against pulmonary infection. Molecular mechanisms controlling…”
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Novel Mouse Model Reveals That Serine Phosphorylation of L-Plastin Is Essential for Effective Splenic Clearance of Pneumococcus
Published in The Journal of immunology (1950) (01-05-2021)“…Asplenia imparts susceptibility to life-threatening sepsis with encapsulated bacteria, such as the pneumococcus. However, the cellular components within the…”
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L-Plastin promotes podosome longevity and supports macrophage motility
Published in Molecular immunology (01-10-2016)“…•Podosome duration is reduced in the absence of l-plastin.•Resident peritoneal macrophages from l-plastin−/− mice do not polarize.•Efficient migration of…”
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Colonization with 19F and other pneumococcal conjugate vaccine serotypes in children in St. Louis, Missouri, USA
Published in Vaccine (03-08-2017)“…•Prevalence of pneumococcal nasopharyngeal colonization of children 0–17years old was 21.2%.•Of 88 isolates, 16 were vaccine-type (11 were 19F), despite 87%…”
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Technical Advance: New in vitro method for assaying the migration of primary B cells using an endothelial monolayer as substrate
Published in Journal of leukocyte biology (01-09-2017)“…The use of activated endothelial cell monolayers as a substrate provides a novel method for analysis of primary B cell migration in vitro. Migration of B cells…”
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Inhaled GM-CSF in neonatal mice provides durable protection against bacterial pneumonia
Published in Science advances (01-08-2019)“…Pneumonia poses profound health threats to preterm infants. Alveolar macrophages (AMs) eliminate inhaled pathogens while maintaining surfactant homeostasis. As…”
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