Search Results - "Szafran, Marcin J."

The activity of CobB1 protein deacetylase contributes to nucleoid compaction in Streptomyces venezuelae spores by increasing HupS affinity for DNA by Duława-Kobeluszczyk, Julia, Strzałka, Agnieszka, Tracz, Michał, Bartyńska, Magdalena, Pawlikiewicz, Katarzyna, Łebkowski, Tomasz, Wróbel, Sara, Szymczak, Justyna, Zarek, Anna, Małecki, Tomasz, Jakimowicz, Dagmara, Szafran, Marcin J

“…Streptomyces are soil bacteria with complex life cycle. During sporulation Streptomyces linear chromosomes become highly compacted so that the genetic material…”
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Spatial rearrangement of the Streptomyces venezuelae linear chromosome during sporogenic development by Szafran, Marcin J., Małecki, Tomasz, Strzałka, Agnieszka, Pawlikiewicz, Katarzyna, Duława, Julia, Zarek, Anna, Kois-Ostrowska, Agnieszka, Findlay, Kim C., Le, Tung B. K., Jakimowicz, Dagmara

“…Bacteria of the genus Streptomyces have a linear chromosome, with a core region and two ‘arms’. During their complex life cycle, these bacteria develop…”
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Author Correction: Spatial rearrangement of the Streptomyces venezuelae linear chromosome during sporogenic development by Szafran, Marcin J., Małecki, Tomasz, Strzałka, Agnieszka, Pawlikiewicz, Katarzyna, Duława, Julia, Zarek, Anna, Kois-Ostrowska, Agnieszka, Findlay, Kim C., Le, Tung B. K., Jakimowicz, Dagmara

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Amsacrine Derivatives Selectively Inhibit Mycobacterial Topoisomerase I (TopA), Impair M. smegmatis Growth and Disturb Chromosome Replication by Szafran, Marcin J, Kołodziej, Marta, Skut, Patrycja, Medapi, Brahmam, Domagała, Agnieszka, Trojanowski, Damian, Zakrzewska-Czerwińska, Jolanta, Sriram, Dharmarajan, Jakimowicz, Dagmara

“…Amsacrine, which inhibits eukaryotic type II topoisomerase via DNA intercalation and stabilization of the cleavable topoisomerase-DNA complex, promotes DNA…”
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Global Chromosome Topology and the Two-Component Systems in Concerted Manner Regulate Transcription in Streptomyces by Gongerowska-Jac, Martyna, Szafran, Marcin J, Mikołajczyk, Jakub, Szymczak, Justyna, Bartyńska, Magdalena, Gierlikowska, Anna, Biały, Sylwia, Elliot, Marie A, Jakimowicz, Dagmara

“…Bacterial gene expression is controlled at multiple levels, with chromosome supercoiling being one of the most global regulators. Global DNA supercoiling is…”
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Compaction and control—the role of chromosome-organizing proteins in Streptomyces by Szafran, Marcin J, Jakimowicz, Dagmara, Elliot, Marie A

“…ABSTRACT Chromosomes are dynamic entities, whose organization and structure depend on the concerted activity of DNA-binding proteins and DNA-processing…”
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C-terminal lysine repeats in Streptomyces topoisomerase I stabilize the enzyme-DNA complex and confer high enzyme processivity by Strzalka, Agnieszka, Szafran, Marcin J, Strick, Terence, Jakimowicz, Dagmara

“…Streptomyces topoisomerase I (TopA) exhibits exceptionally high processivity. The enzyme, as other actinobacterial topoisomerases I, differs from its bacterial…”
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A highly processive actinobacterial topoisomerase I - thoughts on Streptomyces ' demand for an enzyme with a unique C-terminal domain by Szafran, Marcin J, Strzałka, Agnieszka, Jakimowicz, Dagmara

“…Topoisomerase I (TopA) is an essential enzyme that is required to remove excess negative supercoils from chromosomal DNA. Actinobacteria encode unusual TopA…”
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Enhanced binding of an HU homologue under increased DNA supercoiling preserves chromosome organisation and sustains Streptomyces hyphal growth by Strzałka, Agnieszka, Kois-Ostrowska, Agnieszka, Kędra, Magda, Łebkowski, Tomasz, Bieniarz, Grażyna, Szafran, Marcin J, Jakimowicz, Dagmara

“…Bacterial chromosome topology is controlled by topoisomerases and nucleoid-associated proteins (NAPs). While topoisomerases regulate DNA supercoiling, NAPs…”
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