Search Results - "Sywak, Mark"
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Association between BRAF V600E mutation and recurrence of papillary thyroid cancer
Published in Journal of clinical oncology (01-01-2015)“…To investigate the prognostic value of BRAF V600E mutation for the recurrence of papillary thyroid cancer (PTC). This was a retrospective multicenter study of…”
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Patient Age-Associated Mortality Risk Is Differentiated by BRAF V600E Status in Papillary Thyroid Cancer
Published in Journal of clinical oncology (10-02-2018)“…Purpose For the past 65 years, patient age at diagnosis has been widely used as a major mortality risk factor in the risk stratification of papillary thyroid…”
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Outcomes of Advanced Medullary Thyroid Carcinoma in the Era of Targeted Therapy
Published in Annals of surgical oncology (2022)“…Background Medullary thyroid carcinoma (MTC) can be targeted with tyrosine kinase inhibitors (TKIs). We aimed to report the outcomes of surgically managed MTC…”
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Association Between BRAF V600E Mutation and Mortality in Patients With Papillary Thyroid Cancer
Published in JAMA : the journal of the American Medical Association (10-04-2013)“…IMPORTANCE BRAF V600E is a prominent oncogene in papillary thyroid cancer (PTC), but its role in PTC-related patient mortality has not been established…”
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Surgery alone for papillary thyroid microcarcinoma is less costly and more effective than long term active surveillance
Published in Surgery (01-01-2020)“…Papillary thyroid microcarcinoma is a subtype of thyroid cancer that may be managed with active surveillance rather than immediate surgery. Active surveillance…”
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BRAF V600E Status Sharply Differentiates Lymph Node Metastasis-associated Mortality Risk in Papillary Thyroid Cancer
Published in The journal of clinical endocrinology and metabolism (21-10-2021)“…How lymph node metastasis (LNM)-associated mortality risk is affected by BRAF V600E in papillary thyroid cancer (PTC) remains undefined. To study whether BRAF…”
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The Prognostic Value of Tumor Multifocality in Clinical Outcomes of Papillary Thyroid Cancer
Published in The journal of clinical endocrinology and metabolism (01-09-2017)“…Abstract Context Multifocality is often treated as a risk factor for papillary thyroid cancer (PTC), prompting aggressive treatments, but its prognostic value…”
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A Proposed Grading Scheme for Medullary Thyroid Carcinoma Based on Proliferative Activity (Ki-67 and Mitotic Count) and Coagulative Necrosis
Published in The American journal of surgical pathology (01-10-2020)“…We investigated the prognostic value of a range of histologic parameters in medullary thyroid carcinoma (MTC) to design a grading system to predict overall…”
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MicroRNA‐222 and MicroRNA‐146b are tissue and circulating biomarkers of recurrent papillary thyroid cancer
Published in Cancer (15-12-2013)“…BACKGROUND Papillary thyroid cancer (PTC) persistence or recurrence and the need for long‐term surveillance can cause significant inconvenience and morbidity…”
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10
Differential Clinicopathological Risk and Prognosis of Major Papillary Thyroid Cancer Variants
Published in The journal of clinical endocrinology and metabolism (01-01-2016)“…Context: Individualized management, incorporating papillary thyroid cancer (PTC) variant-specific risk, is conceivably a useful treatment strategy for PTC,…”
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11
ASO Visual Abstract: Outcomes of Advanced MTC in the Era of Targeted Therapy
Published in Annals of surgical oncology (2022)Get full text
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12
BRAF V600E status may facilitate decision-making on active surveillance of low-risk papillary thyroid microcarcinoma
Published in European journal of cancer (1990) (01-01-2020)“…Conservative active surveillance has been proposed for low-risk papillary thyroid microcarcinoma (PTMC), defined as ≤1.0 cm and lacking clinical aggressive…”
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Parathyroidectomy for patients with secondary hyperparathyroidism in a changing landscape for the management of end-stage renal disease
Published in Surgery (01-02-2021)“…The landscape of patients with end-stage renal disease is changing with the increasing availability of kidney transplantation. In the near future, a less…”
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Letter to the Editor: Reoperation for Bleeding After Thyroid and Parathyroid Surgery: Incidence, Risk Factors, Prevention, and Management
Published in World journal of surgery (01-07-2020)Get full text
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BRAF V600E Confers Male Sex Disease-Specific Mortality Risk in Patients With Papillary Thyroid Cancer
Published in Journal of clinical oncology (20-09-2018)“…Purpose To test whether the prognostic risk of male sex in papillary thyroid cancer (PTC) is determined by BRAF V600E and can thus be stratified by BRAF…”
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miR-195 and miR-483-5p Identified as Predictors of Poor Prognosis in Adrenocortical Cancer
Published in Clinical cancer research (15-12-2009)“…Purpose: Adrenocortical adenomas are common, whereas adrenocortical carcinomas are rare. Discriminating between benign and malignant adrenocortical tumors…”
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Bi-national Review of Phaeochromocytoma Care: Is ICU Admission Always Necessary?
Published in World journal of surgery (01-03-2021)“…Background Post-operative management after phaeochromocytoma resection includes monitoring of blood pressure and blood sugar, and vigilance for haemorrhage…”
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Primary Hyperparathyroidism
Published in The New England journal of medicine (20-12-2018)“…To the Editor: In his article, Insogna (Sept. 13 issue) 1 notes that “surgical treatment of hyperparathyroidism should incorporate intraoperative PTH…”
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An International Multi-Institutional Validation of Age 55 Years as a Cutoff for Risk Stratification in the AJCC/UICC Staging System for Well-Differentiated Thyroid Cancer
Published in Thyroid (New York, N.Y.) (01-03-2016)“…Age is a critical factor in outcome for patients with well-differentiated thyroid cancer. Currently, age 45 years is used as a cutoff in staging, although…”
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Patience is key for the surgeon in the management of a large haemorrhagic phaeochromocytoma with cardiomyopathy
Published in ANZ journal of surgery (01-11-2024)Get full text
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