Search Results - "Sytwu, H K"
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B lymphocyte-induced maturation protein 1 (BLIMP-1) attenuates autoimmune diabetes in NOD mice by suppressing Th1 and Th17 cells
Published in Diabetologia (01-01-2013)“…Aims/hypothesis Recent reports indicate that B lymphocyte-induced maturation protein 1 (BLIMP-1), encoded by the Prdm1 gene, expands its control over T cells…”
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DNA demethylation of the TIM-3 promoter is critical for its stable expression on T cells
Published in Genes and immunity (01-04-2016)“…The T-cell immunoglobulin and mucin domain-containing protein 3 (TIM-3) is selectively expressed on terminally differentiated T helper 1 (Th1) cells and acts…”
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Transgenic expression of haem oxygenase-1 in pancreatic beta cells protects non-obese mice used as a model of diabetes from autoimmune destruction and prolongs graft survival following islet transplantation
Published in Diabetologia (01-11-2010)“…Aims/hypothesis Haem oxygenase 1 (HO-1) has strong anti-apoptotic, anti-inflammatory and antioxidative effects that help protect cells against various forms of…”
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Transgenic expression of murine chemokine decoy receptor D6 by islets reveals the role of inflammatory CC chemokines in the development of autoimmune diabetes in NOD mice
Published in Diabetologia (01-07-2011)“…Aims/hypothesis Autoimmune diabetes results from a progressive destruction of insulin-producing beta cells in the pancreatic islets by chemokine-attracted…”
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Interleukin (IL)-23 p19 expression induced by IL-1β in human fibroblast-like synoviocytes with rheumatoid arthritis via active nuclear factor-κB and AP-1 dependent pathway
Published in Rheumatology (Oxford, England) (01-08-2007)“…Objectives. To explore the source of the p19 subunit of interleukin-23 (IL-23) in joints with rheumatoid arthritis (RA), the effects of IL-1β and tumour…”
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Kinetics of adaptive immunity to cationic bovine serum albumin-induced membranous nephropathy
Published in Kidney international (01-10-2007)“…Membranous nephropathy is an autoimmune-mediated glomerulonephritis and a major cause of nephrotic syndrome. We studied the kinetics of adaptive immunity in…”
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Adverse Effect on Syngeneic Islet Transplantation by Transgenic Coexpression of Decoy Receptor 3 and Heme Oxygenase-1 in the Islet of NOD Mice
Published in Transplantation proceedings (01-03-2013)“…Abstract Decoy receptor 3 (DcR3) blocks both Fas ligand- and LIGHT-induced pancreatic β-cell damage in autoimmune diabetes. Heme oxygenase 1 (HO-1) possesses…”
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The endogenous immune response modulates the course of IgA-immune complex mediated nephropathy
Published in Kidney international (01-07-2006)“…In animal models of IgA nephropathy, the inevitable endogenous immune response to passively administered antigens alone or in complex with specific IgA mask…”
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Prevention of diabetes in NOD mice by a mutated I-Ab transgene
Published in Diabetes (New York, N.Y.) (01-10-1998)“…Prevention of diabetes in NOD mice by a mutated I-Ab transgene. S M Singer , R Tisch , X D Yang , H K Sytwu , R Liblau and H O McDevitt Department of…”
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Sequence analysis of the Gluconobacter oxydans RecA protein and construction of a recA-deficient mutant
Published in Canadian journal of microbiology (01-04-1999)“…The deduced amino acid sequence of Gluconobacter oxydans RecA protein shows 75.2, 69.4, and 66.2% homology with those from Aquaspirillum magnetotacticum,…”
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The Roles of Fas/APO-1 (CD95) and TNF in Antigen-Induced Programmed Cell Death in T Cell Receptor Transgenic Mice
Published in Immunity (Cambridge, Mass.) (01-07-1996)“…The possible involvement of Fas/APO-1 (CD95) and TNF in antigen-specific AICD of thymocytes and mature T cells has been investigated. Antigenic stimulation in…”
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Involvement of beta 7 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in the development of diabetes in obese diabetic mice
Published in Diabetes (New York, N.Y.) (01-10-1997)“…Involvement of beta 7 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in the development of diabetes in obese diabetic mice. X D Yang , H K…”
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Experimental osteoarthritis induced by surgical realignment of the patella in BALB/c mice
Published in Journal of bone and joint surgery. British volume (01-12-2010)“…The patellofemoral joint is an important source of symptoms in osteoarthritis of the knee. We have used a newly designed surgical model of patellar…”
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Recombinant Adeno-Associated Virus Expressing Human Papillomavirus Type 16 E7 Peptide DNA Fused with Heat Shock Protein DNA as a Potential Vaccine for Cervical Cancer
Published in Journal of Virology (01-03-2000)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Transgenic expression of decoy receptor 3 protects islets from spontaneous and chemical-induced autoimmune destruction in nonobese diabetic mice
Published in The Journal of experimental medicine (19-04-2004)“…Decoy receptor 3 (DCR3) halts both Fas ligand- and LIGHT-induced cell deaths, which are required for pancreatic beta cell damage in autoimmune diabetes. To…”
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Interleukin (IL)-23 p19 expression induced by IL-1 in human fibroblast-like synoviocytes with rheumatoid arthritis via active nuclear factor- B and AP-1 dependent pathway
Published in Rheumatology (Oxford, England) (01-08-2007)“…Objectives. To explore the source of the p19 subunit of interleukin-23 (IL-23) in joints with rheumatoid arthritis (RA), the effects of IL-1β and tumour…”
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The Role of MHC Class II Molecules in Susceptibility to Type I Diabetes: Identification of Peptide Epitopes and Characterization of the T Cell Repertoire
Published in Proceedings of the National Academy of Sciences - PNAS (03-08-1999)“…Susceptibility to type I diabetes is linked to class II MHC alleles in both mouse and man. However, the molecular mechanisms by which MHC molecules mediate…”
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The roles of alpha 4-integrins in the development of insulin-dependent diabetes mellitus
Published in Current topics in microbiology and immunology (1998)“…Lymphocyte/endothelial adhesion followed by transendothelial migration is a key event in the development of organ-specific autoimmunity. Selective interactions…”
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Decoy receptor 3 suppresses RANKL-induced osteoclastogenesis via down-regulating NFATc1 and enhancing cell apoptosis
Published in Rheumatology (Oxford, England) (01-04-2013)“…Decoy receptor 3 (DCR3) has been known to modulate immune functions of monocyte or macrophage. In the present study, we investigated the mechanism and the…”
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Application of Single-chain Snti-Ctla-4 Fv in Autoimmune Diabetes: from In Vitro Immunomodulatory Effects to Transgenic Non-obese Diabetic Mice
Published in Clinical Immunology (01-01-2006)Get full text
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