Search Results - "Systrom, David"

Fatigue, Sleep, and Autoimmune and Related Disorders by Zielinski, Mark R, Systrom, David M, Rose, Noel R

“…Profound and debilitating fatigue is the most common complaint reported among individuals with autoimmune disease, such as systemic lupus erythematosus,…”
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Persistent Exertional Intolerance After COVID-19: Insights From Invasive Cardiopulmonary Exercise Testing by Singh, Inderjit, Joseph, Phillip, Heerdt, Paul M, Cullinan, Marjorie, Lutchmansingh, Denyse D, Gulati, Mridu, Possick, Jennifer D, Systrom, David M, Waxman, Aaron B

“…Some patients with COVID-19 who have recovered from the acute infection after experiencing only mild symptoms continue to exhibit persistent exertional…”
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Right Ventricular-Arterial Uncoupling During Exercise in Heart Failure With Preserved Ejection Fraction: Role of Pulmonary Vascular Dysfunction by Singh, Inderjit, Rahaghi, Farbod N, Naeije, Robert, Oliveira, Rudolf K F, Systrom, David M, Waxman, Aaron B

“…Right ventricular (RV) dysfunction is associated with shortened life expectancy in heart failure with preserved ejection fraction (HFpEF). The contribution of…”
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Insights From Invasive Cardiopulmonary Exercise Testing of Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome by Joseph, Phillip, Arevalo, Carlo, Oliveira, Rudolf K.F., Faria-Urbina, Mariana, Felsenstein, Donna, Oaklander, Anne Louise, Systrom, David M.

“…Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) affects tens of millions worldwide; the causes of exertional intolerance are poorly understood. The…”
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Multisystem Involvement in Post‐Acute Sequelae of Coronavirus Disease 19 by Novak, Peter, Mukerji, Shibani S., Alabsi, Haitham S., Systrom, David, Marciano, Sadie P., Felsenstein, Donna, Mullally, William J., Pilgrim, David M.

“…Objective The purpose of this study was to describe cerebrovascular, neuropathic, and autonomic features of post‐acute sequelae of coronavirus disease 2019…”
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Myalgic Encephalomyelitis—Chronic Fatigue Syndrome Common Data Element item content analysis by Slavin, Mary D, Bailey, Hannah M, Hickey, Emily J, Vasudevan, Ananya, Ledingham, Aileen, Tannenbaum, Linda, Bateman, Lucinda, Kaufman, David L, Peterson, Daniel L, Ruhoy, Ilene S, Systrom, David M, Felsenstein, Donna, Kazis, Lewis E

“…Introduction Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a multisystem chronic disease estimated to affect 836,000–2.5 million individuals…”
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Neurovascular Dysregulation and Acute Exercise Intolerance in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Placebo-Controlled Trial of Pyridostigmine by Joseph, Phillip, Pari, Rosa, Miller, Sarah, Warren, Arabella, Stovall, Mary Catherine, Squires, Johanna, Chang, Chia-Jung, Xiao, Wenzhong, Waxman, Aaron B, Systrom, David M

“…Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by intractable fatigue, postexertional malaise, and orthostatic intolerance, but…”
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Orthostatic intolerance with tachycardia (postural tachycardia syndrome) and without (hypocapnic cerebral hypoperfusion) represent a spectrum of the same disorder by Novak, Peter, Systrom, David M., Witte, Alexandra, Marciano, Sadie P.

“…Background Spectrum of chronic orthostatic intolerance without orthostatic hypotension includes postural tachycardia syndrome (POTS), with orthostatic…”
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The Invasive Cardiopulmonary Exercise Test by MARON, Bradley A, COCKRILL, Barbara A, WAXMAN, Aaron B, SYSTROM, David M

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Dynamic regulation of circulating microRNA during acute exhaustive exercise and sustained aerobic exercise training by Baggish, Aaron L., Hale, Andrew, Weiner, Rory B., Lewis, Gregory D., Systrom, David, Wang, Francis, Wang, Thomas J., Chan, Stephen Y.

“…Non‐technical summary  MicroRNA (miRNA) molecules are essential intracellular mediators of numerous biological processes including angiogenesis, inflammation,…”
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Postural orthostatic tachycardia syndrome (POTS): State of the science and clinical care from a 2019 National Institutes of Health Expert Consensus Meeting - Part 1 by Vernino, Steven, Bourne, Kate M., Stiles, Lauren E., Grubb, Blair P., Fedorowski, Artur, Stewart, Julian M., Arnold, Amy C., Pace, Laura A., Axelsson, Jonas, Boris, Jeffrey R., Moak, Jeffrey P., Goodman, Brent P., Chémali, Kamal R., Chung, Tae H., Goldstein, David S., Diedrich, Andre, Miglis, Mitchell G., Cortez, Melissa M., Miller, Amanda J., Freeman, Roy, Biaggioni, Italo, Rowe, Peter C., Sheldon, Robert S., Shibao, Cyndya A., Systrom, David M., Cook, Glen A., Doherty, Taylor A., Abdallah, Hasan I., Darbari, Anil, Raj, Satish R.

“…Postural orthostatic tachycardia syndrome (POTS) is a chronic and often disabling disorder characterized by orthostatic intolerance with excessive heart rate…”
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Exercise-Induced Pulmonary Arterial Hypertension by TOLLE, James J, WAXMAN, Aaron B, VAN HORN, Teresa L, PAPPAGIANOPOULOS, Paul P, SYSTROM, David M

“…The clinical relevance of exercise-induced pulmonary arterial hypertension (PAH) is uncertain, and its existence has never been well studied by direct…”
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Measuring central pulmonary pressures during exercise in COPD: how to cope with respiratory effects by BOERRIGTER, Bart G, WAXMAN, Aaron B, WESTERHOF, Nico, VONK-NOORDEGRAAF, Anton, SYSTROM, David M

“…Respiratory influences are major confounders when evaluating central haemodynamics during exercise. We studied four different methods to assess mean pulmonary…”
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Pulmonary Vascular Distensibility and Early Pulmonary Vascular Remodeling in Pulmonary Hypertension by Singh, Inderjit, Oliveira, Rudolf K.F., Naeije, Robert, Rahaghi, Farbod N., Oldham, William M., Systrom, David M., Waxman, Aaron B.

“…Exercise stress testing of the pulmonary circulation may uncover decreased pulmonary vascular (PV) distensibility as a cause of impaired aerobic exercise…”
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Exercise Pathophysiology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Postacute Sequelae of SARS-CoV-2: More in Common Than Not? by Joseph, Phillip, Singh, Inderjit, Oliveira, Rudolf, Capone, Christine A, Mullen, Mary P, Cook, Dane B, Stovall, Mary Catherine, Squires, Johanna, Madsen, Kristine, Waxman, Aaron B, Systrom, David M

“…Postacute sequelae of SARS-CoV-2 (PASC) is a long-term consequence of acute infection from COVID-19. Clinical overlap between PASC and myalgic…”
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Sex-Related Differences in Dynamic Right Ventricular-Pulmonary Vascular Coupling in Heart Failure With Preserved Ejection Fraction by Singh, Inderjit, Oliveira, Rudolf K.F., Heerdt, Paul M., Pari, Rosa, Systrom, David M., Waxman, Aaron B.

“…Right ventricular (RV) dysfunction is associated with poorer outcomes in heart failure with preserved ejection fraction (HFpEF). Although female subjects are…”
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Metabolic signatures of exercise in human plasma by Lewis, Gregory D, Farrell, Laurie, Wood, Malissa J, Martinovic, Maryann, Arany, Zoltan, Rowe, Glenn C, Souza, Amanda, Cheng, Susan, McCabe, Elizabeth L, Yang, Elaine, Shi, Xu, Deo, Rahul, Roth, Frederick P, Asnani, Aarti, Rhee, Eugene P, Systrom, David M, Semigran, Marc J, Vasan, Ramachandran S, Carr, Steven A, Wang, Thomas J, Sabatine, Marc S, Clish, Clary B, Gerszten, Robert E

“…Exercise provides numerous salutary effects, but our understanding of how these occur is limited. To gain a clearer picture of exercise-induced metabolic…”
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Mismatch between subjective and objective dysautonomia by Novak, Peter, Systrom, David M., Marciano, Sadie P., Knief, Alexandra, Felsenstein, Donna, Giannetti, Matthew P., Hamilton, Matthew J., Nicoloro-SantaBarbara, Jennifer, Saco, Tara V., Castells, Mariana, Farhad, Khosro, Pilgrim, David M., Mullally, William J.

“…Autonomic symptom questionnaires are frequently used to assess dysautonomia. It is unknown whether subjective dysautonomia obtained from autonomic…”
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Age-related upper limits of normal for maximum upright exercise pulmonary haemodynamics by Oliveira, Rudolf K F, Agarwal, Manyoo, Tracy, Julie A, Karin, Abbey L, Opotowsky, Alexander R, Waxman, Aaron B, Systrom, David M

“…The exercise definition of pulmonary hypertension was eliminated from the pulmonary hypertension guidelines in part due to uncertainty of the upper limits of…”
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Invasive cardiopulmonary exercise testing in the evaluation of unexplained dyspnea: Insights from a multidisciplinary dyspnea center by Huang, Wei, Resch, Stephen, Oliveira, Rudolf KF, Cockrill, Barbara A, Systrom, David M, Waxman, Aaron B

“…Background Unexplained dyspnea is a common diagnosis that often results in repeated diagnostic testing and even delayed treatments while a determination of the…”
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