Search Results - "Sys, Gwen"

Playing the infinite in sarcoma care and research by Sys, Gwen M L

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The in ovo CAM-assay as a xenograft model for sarcoma by Sys, Gwen M L, Lapeire, Lore, Stevens, Nikita, Favoreel, Herman, Forsyth, Ramses, Bracke, Marc, De Wever, Olivier

“…Sarcoma is a very rare disease that is heterogeneous in nature, all hampering the development of new therapies. Sarcoma patients are ideal candidates for…”
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Biological Sample Collection to Advance Research and Treatment: A Fight Osteosarcoma Through European Research and Euro Ewing Consortium Statement by Green, Darrell, van Ewijk, Roelof, Tirtei, Elisa, Andreou, Dimosthenis, Baecklund, Fredrik, Baumhoer, Daniel, Bielack, Stefan S, Botchu, Rajesh, Boye, Kjetil, Brennan, Bernadette, Capra, Michael, Cottone, Lucia, Dirksen, Uta, Fagioli, Franca, Fernandez, Natalia, Flanagan, Adrienne M, Gambarotti, Marco, Gaspar, Nathalie, Gelderblom, Hans, Gerrand, Craig, Gomez-Mascard, Anne, Hardes, Jendrik, Hecker-Nolting, Stefanie, Kabickova, Edita, Kager, Leo, Kanerva, Jukka, Kester, Lennart A, Kuijjer, Marieke L, Laurence, Valérie, Lervat, Cyril, Marchais, Antonin, Marec-Berard, Perrine, Mendes, Cristina, Merks, Johannes H M, Ory, Benjamin, Palmerini, Emanuela, Pantziarka, Pan, Papakonstantinou, Evgenia, Piperno-Neumann, Sophie, Raciborska, Anna, Roundhill, Elizabeth A, Rutkauskaite, Vilma, Safwat, Akmal, Scotlandi, Katia, Staals, Eric L, Strauss, Sandra J, Surdez, Didier, Sys, Gwen M L, Tabone, Marie-Dominique, Toulmonde, Maud, Valverde, Claudia, van de Sande, Michiel A J, Wörtler, Klaus, Campbell-Hewson, Quentin, McCabe, Martin G, Nathrath, Michaela

“…Osteosarcoma and Ewing sarcoma are bone tumors mostly diagnosed in children, adolescents, and young adults. Despite multimodal therapy, morbidity is high and…”
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RAF1-rearranged Spindle Cell Mesenchymal Tumor With Calcification and Heterotopic Ossification: A Case Report and Review of Literature by Cordier, Fleur, Loontiens, Siebe, Van der Meulen, Joni, Lapeire, Lore, van Ramshorst, Gabrielle H., Sys, Gwen, Van Dorpe, Jo, Creytens, David

“…We report an exceptional case of a spindle cell mesenchymal tumor with S100 and CD34 co-reactivity, which harbored a SLMAP::RAF1 fusion. To the best of our…”
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Expandable distal femur megaprosthesis: A European Musculoskeletal Oncology Society study on 299 cases by Staals, Eric Lodewijk, Sambri, Andrea, Campanacci, Domenico Andrea, Muratori, Francesco, Leithner, Andreas, Gilg, Magdalena Maria, Gortzak, Yair, Van De Sande, Michiel, Dierselhuis, Edwin, Mascard, Eric, Windhager, Reinhard, Funovics, Philipp, Schinhan, Martina, Vyrva, Oleg, Sys, Gwen, Bolshakov, Nikolay, Aston, Will, Gikas, Panagiotas, Schubert, Thomas, Jeys, Lee, Abudu, Adesegun, Manfrini, Marco, Donati, Davide Maria

“…Background and Objectives Expandable distal femur prostheses have become more popular over the last decades, but scientific data is limited. Methods A…”
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Vacuolar H+ ATPase expression and activity is required for Rab27B‐dependent invasive growth and metastasis of breast cancer by Hendrix, An, Sormunen, Raija, Westbroek, Wendy, Lambein, Kathleen, Denys, Hannelore, Sys, Gwen, Braems, Geert, Broecke, Rudy, Cocquyt, Veronique, Gespach, Christian, Bracke, Marc, Wever, Olivier

“…The secretory Rab27B small GTPase promotes invasive growth and metastasis in estrogen receptor (ER) α‐positive breast cancer cells by orchestrating the…”
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Generation of post-surgical minimal residual disease models to investigate metastasis in soft tissue sarcoma patient-derived orthotopic xenografts by Fischer, Suzanne, Creytens, David, Gijsels, Stefanie, Descamps, Benedicte, Lapeire, Lore, Hendrix, An, Sys, Gwen, De Wever, Olivier

“…Despite optimal multimodal treatment including surgical resection, 50%–80% of high-grade soft tissue sarcoma (STS) patients metastasize. Here, we present a…”
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Tumor grafts derived from sarcoma patients retain tumor morphology, viability, and invasion potential and indicate disease outcomes in the chick chorioallantoic membrane model by Sys, Gwen, Van Bockstal, Mieke, Forsyth, Ramses, Balke, Maurice, Poffyn, Bart, Uyttendaele, Dirk, Bracke, Marc, De Wever, Olivier

“…Highlights ► Xenotransplanted sarcomas on the CAM retain histological characteristics and functional behavior of the original tumors. ► Xenoraft viability on…”
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Late Lung Metastasis in a Patient with a Clear Cell Chondrosarcoma: An Indication for a Life-Long Follow-Up? by West, Paulien, Jacobs, Celine, Saerens, Michael, Creytens, David, Sys, Gwen, Lapeire, Lore

“…Background. Clear cell chondrosarcoma (CCCS) is a rare subtype of chondrosarcoma and comprises between 1.6% and 2.5% of all chondrosarcoma. They are known to…”
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Identification and validation of extracellular vesicle reference genes for the normalization of RT‐qPCR data by Pinheiro, Cláudio, Guilbert, Niké, Lippens, Lien, Roux, Quentin, Boiy, Robin, Fischer, Suzanne, Van Dorpe, Sofie, De Craene, Bram, Berx, Geert, Boterberg, Tom, Sys, Gwen, Denys, Hannelore, Miinalainen, Ilkka, Mestdagh, Pieter, Vandesompele, Jo, De Wever, Olivier, Hendrix, An

“…Extracellular vesicles (EVs) contain a plethora of biomolecules, including nucleic acids, with diverse diagnostic and therapeutic application potential…”
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Post‐operative minimal residual disease models to study metastatic relapse in soft‐tissue sarcoma patient‐derived xenografts by Fischer, Suzanne, Creytens, David, De Geyter, Sofie, De Vlieghere, Elly, Pattyn, Piet, Bekaert, Sarah‐Lee, Durinck, Kaat, Van Roy, Nadine, Hendrix, An, Lapeire, Lore, Sys, Gwen, De Wever, Olivier

“…[...]out of the three O-Swiss that showed metastases, only one had been preceded by a primary tumour (MRD period of 36.5 weeks). [...]MRD-PDX developed by…”
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Are stand-alone cages sufficient for anterior lumbar interbody fusion? by Zhang, Ji-dong, Poffyn, Bart, Sys, Gwen, Uyttendaele, Dirk

“…Anterior lumbar interbody fusion (ALIF) has increased in popularity because it has advantages over posterior fusion. Because there is disagreement about the…”
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Radiographic analysis of extracorporeally irradiated autografts by Poffyn, Bart, Sys, Gwen, Van Maele, Georges, Van Hoorebeke, Luc, Forsyth, Ramses, Verstraete, Koenraad, Uyttendaele, Dirk

“…Objective To analyse the long-term radiographic findings of intercalary, pure osteoarticular, and composite bone grafts in patients with primary bone sarcoma…”
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Enhancing rotational placement of reconstruction prostheses of the distal femur after sarcoma resection by De Smet, Arne, Verrewaere, Dries, Sys, Gwen

“…•Currently there are no accepted international guidelines for the correct placement of reconstruction prostheses in the axial plane.•The linea aspera is not a…”
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Diagnosis and monitoring denosumab therapy of giant cell tumors of bone: radiologic-pathologic correlation by Lejoly, Maryse, Van Den Berghe, Thomas, Creytens, David, Huysse, Wouter, Lapeire, Lore, Sys, Gwen, Verstraete, Koenraad

“…Objective To determine the value of CT and dynamic contrast-enhanced (DCE-)MRI for monitoring denosumab therapy of giant cell tumors of bone (GCTB) by…”
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Pelvic exenteration with neurovascular and bony resections for gynaecological tumours: a systematic review by Denys, Andreas, Thielemans, Sofie, Rawand, Salihi, Gwen, Sys, Philippe, Tummers, Van Ramshorst, Gabriëlle, Demuytere, Jesse

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Oncological and functional outcomes after high or total sacrectomy: a systematic review by Braeckman, Nathalie, Kerckhove, Eva, Sys, Gwen, Van Ramshorst, Gabriëlle, Demuytere, Jesse

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NGS-analysis to the rescue: dual checkpoint inhibition in metastatic osteosarcoma - a case report and review of the literature by Nuytemans, Laure, Sys, Gwen, Creytens, David, Lapeire, Lore

“…: The prognosis and treatment of metastatic osteosarcoma have not changed in the last decades and the responses to chemotherapy in this setting are…”
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Spindle cell/sclerosing rhabdomyosarcoma with a novel YAP1-MAML2 fusion in a 1-year-old: not all strongly TRK-expressing spindle cell sarcomas in infants are infantile fibrosarcomas by Cordier, Fleur, Ameloot, Eline, Dhooge, Catharina, Lapeire, Lore, Sys, Gwen, Van Dorpe, Jo, Creytens, David

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Metastasized orthotopic patient-derived xenografts as preclinical model to guide therapeutic decision making in soft tissue sarcoma patients by Fischer, Suzanne, De Vlieghere, Elly, Creytens, David, De Wever, Olivier, Hendrix, An, Lapeire, Lore, Sys, Gwen

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