Search Results - "Syrigos, Kostas N"

Disparities in colorectal cancer in African-Americans vs Whites： Before and after diagnosis by Dimou, Anastasios, Syrigos, Kostas N, Saif, Muhammad Wasif

“…There are differences between African-American and white patients with colorectal cancer, concerning their characteristics before and after diagnosis. Whites…”
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The role of mTOR in the management of solid tumors: An overview by Strimpakos, Alex S, Karapanagiotou, Eleni M, Saif, M. Wasif, Syrigos, Kostas N

“…Summary Mammalian target of rapamycin (mTOR) is a key protein kinase controlling signal transduction from various growth factors and upstream proteins to the…”
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Pancreatic cancer: from molecular pathogenesis to targeted therapy by Strimpakos, Alexios, Saif, Muhammad W., Syrigos, Kostas N.

“…Pancreatic cancer is a deadly malignancy with still high mortality and poor survival despite the significant advances in understanding, diagnosis, and access…”
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The Biological Role of PI3K Pathway in Lung Cancer by Sarris, Evangelos G, Saif, Muhammad W, Syrigos, Kostas N

“…Lung cancer is the primary cause of cancer-related mortality worldwide and although improvements in treatment have been achieved over the last few years,…”
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Head and neck cancer in the elderly: An overview on the treatment modalities by Syrigos, Kostas N, Karachalios, Dimitris, Karapanagiotou, Eleni M, Nutting, Christopher M, Manolopoulos, Leonidas, Harrington, Kevin J

“…Summary The percentage of elderly people with head and neck cancers (HNC) is rising due to increasing average lifespan. As with younger patients, elderly…”
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Hypersensitivity reactions to docetaxel: retrospective evaluation and development of a desensitization protocol by Syrigou, Ekaterini, Dannos, Ioannis, Kotteas, Elias, Makrilia, Nektaria, Tourkantonis, Ioannis, Dilana, Kalliopi, Gkiozos, Ioannis, Saif, Muhammad Wasif, Syrigos, Kostas N

“…Docetaxel (DT) is an extensively used taxane, frequently associated with hypersensitivity reactions. The aim of this study was to record the epidemiological…”
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Targeted therapy for gastrointestinal stromal tumors: current status and future perspectives by Papaetis, Georgios S., Syrigos, Kostas N.

“…Gastrointestinal stromal tumors (GISTs) present 80% of gastrointestinal tract mesenchymal tumors, with systemic chemotherapy and radiotherapy being unable to…”
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Hypersensitivity reactions to antineoplastic agents: an overview by Syrigou, Ekaterini, Makrilia, Nektaria, Koti, Ioanna, Saif, Muhammad W, Syrigos, Kostas N

“…Hypersensitivity reactions to antineoplastic agents are defined as unexpected reactions with signs and symptoms inconsistent with known toxicity of…”
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The molecular targets for the diagnosis and treatment of pancreatic cancer by Strimpakos, Alexios S, Syrigos, Kostas N, Saif, Muhammad Wasif

“…Pancreatic cancer is considered an aggressive malignancy that responds poorly to current treatments and therefore has a dismal survival rate. This disease is…”
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The safety and efficacy of Onivyde (irinotecan liposome injection) for the treatment of metastatic pancreatic cancer following gemcitabine-based therapy by Passero, Frank C., Grapsa, Dimitra, Syrigos, Kostas N., Saif, Muhammad Wasif

“…Introduction: Patients with advanced and metastatic pancreatic cancer refractory to gemcitabine based therapy have a dismal prognosis and limited therapeutic…”
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Therapy-induced Toxicity of the Lungs: An Overview by CHARPIDOU, Andriani G, GKIOZOS, Ioannis, TSIMPOUKIS, Sotirios, APOSTOLAKI, Despoina, DILANA, Kalliopi D, KARAPANAGIOTOU, Eleni M, SYRIGOS, Kostas N

“…Pulmonary toxicity induced by novel antineoplastic agents has not been well characterized because of the simultaneous or sequential use of drugs and a…”
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The Clinical Significance of Serum Markers of Bone Turnover in NSCLC Patients: Surveillance, Management and Prognostic Implications by TERPOS, Evangelos, KIAGIA, Maria, KARAPANAGIOTOU, Eleni M, CHARPIDOU, Adrianni, DIANA, Kaliopi D, NASOTHIMIOU, Efthimia, HARRINGTON, Kevin J, POLYZOS, A, SYRIGOS, Kostas N

“…The purpose of this study was to investigate various serum markers of bone turnover in non-small cell lung cancer patients (NSCLC) in the presence or absence…”
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Mixed Acinar-Neuroendocrine Carcinoma of the Pancreas with Neuroendocrine Predominance by Ogbonna, Onyekachi Henry, Garcon, Marie Carmel, Syrigos, Kostas N., Saif, Muhammad Wasif

“…Background. Pancreatic tumors are rare and could arise from either the exocrine (ductal and acinar cells) or the endocrine (neuroendocrine cells) components of…”
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Facial hypertrichosis and trichomegaly developing in patients treated with the epidermal growth factor receptor inhibitor erlotinib by Vergou, Theognosia, MD, Stratigos, Alexander J., MD, PhD, Karapanagiotou, Eleni M., MD, Matekovits, Athina E., MD, Dilana, Kalliopi D., MD, Tsimboukis, Sotirios, MD, Antoniou, Christina, MD, PhD, Chasapi, Vassiliki, MD, Syrigos, Kostas N., MD, PhD

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The Role of EGFR Inhibitors in the Treatment of Metastatic Anal Canal Carcinoma: A Case Series by Shahrokni, Armin, Syrigos, Kostas N., Kontny, Ewa, Saif, Muhammad Wasif

“…Anal cancer patients who have exhibited disease progression after having received all approved drugs pose a major therapeutic challenge. In addition to…”
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Sunitinib: A Multitargeted Receptor Tyrosine Kinase Inhibitor in the Era of Molecular Cancer Therapies by Papaetis, Georgios S., Syrigos, Kostas N.

“…Sunitinib is an oral oxindole multitargeted kinase inhibitor that inhibits certain receptor tyrosine kinases (RTKs). These include vascular endothelial growth…”
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Carboplatin-Pemetrexed Adjuvant Chemotherapy in Resected Non-small Cell Lung Cancer (NSCLC): A Phase II Study by KARAPANAGIOTOU, Eleni M, BOURA, Paraskevi G, PAPAMICHALIS, George, KONSTANTINOU, Marios, SEPSAS, Evangellos, CHAMALAKIS, George, SIMSIRIS, Panagiotis, GKIOZOS, Ioannis, SYRIGOS, Kostas N

“…Background: The aim of this study was to determine the progression-free survival (PFS) and toxicity associated with adjuvant administration of carboplatin and…”
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Role of Vitamin D in the Prevention of Pancreatic Cancer by Bulathsinghala, Pubudu, Syrigos, Kostas N., Saif, Muhammad W.

“…Pancreatic cancer is a malignancy of poor prognosis which is mostly diagnosed at advanced stages. Current treatment modalities are very limited creating great…”
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Bevacizumab-Induced Hypertension: Pathogenesis and Management by Syrigos, Kostas N., Karapanagiotou, Eleni, Boura, Paraskevi, Manegold, Christian, Harrington, Kevin

“…Bevacizumab, a recombinant humanized monoclonal antibody targeting the vascular endothelial growth factor (VEGF), has been approved in the US as first- and…”
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Chemotherapy-induced neutropenia in lung cancer patients: The role of antibiotic prophylaxis by Kouranos, Vasileios, Dimopoulos, George, Vassias, Antonios, Syrigos, Kostas N

“…Highlights ► We performed a PubMed literature search of manuscripts published until May 2011. ► Quinolones and trimethoprim/sulfamethoxazole were most…”
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