Search Results - "Symons, J.A"

Automated preoperative assessment of endothelial dysfunction and risk stratification for perioperative myocardial injury in patients undergoing non-cardiac surgery by McIlroy, D.R., Chan, M.T.V., Wallace, S.K., Symons, J.A., Koo, E.G.Y., Chu, L.C.Y., Myles, P.S.

“…Myocardial injury after non-cardiac surgery (MINS) is a common complication with associated serious morbidity and mortality. Endothelial dysfunction might play…”
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Pan-Genotypic Evaluation of AL-335, a Clinical Stage Uridine Analogue Inhibitor of Hepatitis C Virus Polymerase by Deval, J, Fung, A, Behera, I, Jin, Z, Stoycheva, A, Blatt, L.M, Wang, G, Dyatkina, N, Prhavc, M, Symons, J.A, Smith, D.B, Beigelman, L

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P0679 : Derisking the potential for mitochondrial toxicity of nucleoside analogs by Jin, Z, Deval, J, Symons, J.A, Tan, H, Shaw, K, Chanda, S.M, Zhang, Q, Tam, Y, Blatt, L.M, Wang, G, Dyatkina, N, Beigelman, L, Smith, D.B

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P0682 : Preclinical characterization of AL-335, a potent uridine based nucleoside polymerase inhibitor for the treatment of chronic hepatitis C by Tan, H, Shaw, K, Jekel, A, Deval, J, Jin, Z, Fung, A, Tam, Y, Blatt, L.M, Chanda, S.M, Wang, G, Prhavc, M, Serebryany, V, Zhang, Q, Symons, J.A, Beigelman, L, Smith, D.B

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1222 IN VITRO RESISTANCE TO ALS-2200, A POTENT NUCLEOTIDE POLYMERASE INHIBITOR FOR THE TREATMENT OF CHRONIC HEPATITIS C by Tan, H, Jekle, A, Kang, H, Moy, C, Deval, J, Tigges, A, Zhang, E, Jiang, M, Andzinski, A, Dyatkina, N, Wang, G, Rijnbrand, R, Kieffer, T.L, Blatt, L.M, Beigelman, L, Smith, D.B, Symons, J.A

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1219 VX-135, A POTENT SINGLE DIASTEREOMER OF ALS-2200, FOR THE TREATMENT OF CHRONIC HEPATITIS C by Tan, H, Deval, J, Kang, H, Moy, C, Jin, Z, Jiang, M, Ardzinski, A, Rijnbrand, R, Kieffer, T, Blatt, L.M, Chanda, S.M, Dyatkina, N, Wang, G, Zhang, Q, Symons, J.A, Beigelman, L, Smith, D.B

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766 DEVELOPMENT OF A HYPERGLYCOSYLATEDIFN ALFAC0N1 (CIFN): TOWARDS BIMONTHLY OR MONTHLY DOSING FOR ANTIVIRAL THERAPIES IN DISEASES SUCH AS CHRONIC HEPATITIS C by Hong, J, Taylor, J.S, Julander, J.G, Zhang, Q, Stoycheva, A.D, Tan, H, Moy, C.V, Chanda, S, Symons, J.A, Beigelman, L.N, Blatt, L.M

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Myocardial protection with volatile anaesthetic agents during coronary artery bypass surgery: a meta-analysis by Symons, J.A., Myles, P.S.

“…Previous studies have investigated the role of volatile anaesthetic agents in myocardial protection during coronary artery bypass graft (CABG) surgery, and…”
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THU-226 - Pan-Genotypic Evaluation of AL-335, a Clinical Stage Uridine Analogue Inhibitor of Hepatitis C Virus Polymerase by Deval, J., Fung, A., Behera, I., Jin, Z., Stoycheva, A., Blatt, L.M., Wang, G., Dyatkina, N., Prhavc, M., Symons, J.A., Smith, D.B., Beigelman, L.

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Interferon-gamma induced clearance of an HCV subgenomic replicon: a role for nitric oxide? by Moffatt, A., Fletcher, S., Bartenschlager, R., Devos, R., Symons, J.A.

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Use of the HCV subgenomic replicon for the selection and characterization of variants with reduced susceptibility to interferon alpha-2A by Laxton, C., Hobbs, E., Fletcher, S., Symons, J.A, Bartenschlager, R., Graves, M., Devos, R., Najera, I.

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Immune modulation by proteins secreted from cells infected by vaccinia virus by Smith, G.L, Symons, J.A, Alcami, A

“…Vaccinia virus comprises the live vaccine that was used for vaccination against smallpox. Following the eradication of smallpox, vaccinia virus was developed…”
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A soluble form of the interleukin-1 receptor produced by a human B cell line by Symons, J.A., Duff, G.W.

“…A soluble protein that binds specifically to interleukin-1 (IL-1)β was released from a B cell line (Raji). The covalently cross-linked binding protein/ […”
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Identification of an interleukin-1 beta binding protein in human plasma by Eastgate, J.A., Symons, J.A., Duff, G.W.

“…A covalent cross-linking technique was used to bind iodinated interleukin-1 (IL1) alpha and beta to plasma proteins. One specific IL1 beta binding protein was…”
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Kinetics of IL1 beta mRNA and protein accumulation in human mononuclear cells by di Giovine, F S, Symons, J A, Duff, G W

“…Interleukin 1 beta (IL1 beta) is an inducible polypeptide with many roles in host defence and homoeostasis. It has also been implicated as a mediator of…”
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Lymphocytic activation in peripheral blood and cerebrospinal fluid during the course of chronic relapsing experimental allergic encephalomyelitis by Suckling, A J, Baron, P W, Symons, J A, Rumsby, M G

“…A monoclonal antibody against the human interleukin-2 receptor (anti-Tac) has been found to cross-react with an antigen on the surface of guinea pig…”
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Chronic relapsing experimental allergic encephalomyelitis. Inhibition of lymphocyte mitogenesis by disease-related serum factors by Symons, J A, Suckling, A J, Bundick, R V, Rumsby, M G

“…Peripheral blood mononuclear cells (PBMC) from strain 13 guinea pigs at various stages of chronic relapsing experimental allergic encephalomyelitis (CREAE)…”
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Soluble CD4 in patients with rheumatoid arthritis and osteoarthritis by Symons, J A, McCulloch, J F, Wood, N C, Duff, G W

“…An ELISA was used to measure the soluble form of the leukocyte surface antigen CD4 (sCD4) in the sera and synovial fluids (SF) of patients with rheumatic…”
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