Search Results - "Symmons, Deborah P"

Association of HLA-DRB1 Haplotypes With Rheumatoid Arthritis Severity, Mortality, and Treatment Response by Viatte, Sebastien, Plant, Darren, Han, Buhm, Fu, Bo, Yarwood, Annie, Thomson, Wendy, Symmons, Deborah P. M, Worthington, Jane, Young, Adam, Hyrich, Kimme L, Morgan, Ann W, Wilson, Anthony G, Isaacs, John D, Raychaudhuri, Soumya, Barton, Anne

“…IMPORTANCE: Advances have been made in identifying genetic susceptibility loci for autoimmune diseases, but evidence is needed regarding their association with…”
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Epidemiology of CVD in rheumatic disease, with a focus on RA and SLE by Symmons, Deborah P. M, Gabriel, Sherine E

“…Traditional cardiovascular risk factors combine, in the context of inflammatory rheumatic diseases, with disease-related and treatment-related risk factors, to…”
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Prediction of primary non-response to methotrexate therapy using demographic, clinical and psychosocial variables: results from the UK Rheumatoid Arthritis Medication Study (RAMS) by Sergeant, Jamie C, Hyrich, Kimme L, Anderson, James, Kopec-Harding, Kamilla, Hope, Holly F, Symmons, Deborah P M, Barton, Anne, Verstappen, Suzanne M M

“…Methotrexate (MTX) remains the disease-modifying anti-rheumatic drug of first choice in rheumatoid arthritis (RA) but response varies. Predicting non-response…”
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Impact of concomitant use of DMARDs on the persistence with anti-TNF therapies in patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register by Soliman, Moetaza M, Ashcroft, Darren M, Watson, Kath D, Lunt, Mark, Symmons, Deborah P M, Hyrich, Kimme L

“…To evaluate the effect of different concomitant disease modifying antirheumatic drugs (DMARDs) on the persistence with antitumour necrosis factor (anti-TNF)…”
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Specific interaction between genotype, smoking and autoimmunity to citrullinated α-enolase in the etiology of rheumatoid arthritis by Padyukov, Leonid, Lundberg, Karin, Symmons, Deborah P M, Ding, Bo, Fisher, Benjamin A, Alfredsson, Lars, Malmström, Vivianne, Mahdi, Hiba, Klareskog, Lars, Charles, Peter, Venables, Patrick J, Rönnelid, Johan, Plant, Darren, Källberg, Henrik

“…Gene-environment associations are important in rheumatoid arthritis (RA) susceptibility, with an association existing between smoking, HLA- DRB1 'shared…”
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Anti-TNF therapies and pregnancy: outcome of 130 pregnancies in the British Society for Rheumatology Biologics Register by Verstappen, Suzanne M M, King, Yvonne, Watson, Kath D, Symmons, Deborah P M, Hyrich, Kimme L

“…The British Society for Rheumatology Biologics Register (BSRBR) has collected data on adverse events including pregnancies in patients with rheumatoid…”
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Modifiable risk factors for RA: prevention, better than cure? by Lahiri, Manjari, Morgan, Catharine, Symmons, Deborah P. M., Bruce, Ian N.

“…Objective. To perform a meta-synthesis of the evidence for modifiable lifestyle risk factors for inflammatory polyarthritis (IP) and RA. Methods. We performed…”
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Risk factors for oral methotrexate failure in patients with inflammatory polyarthritis: results from a UK prospective cohort study by Bluett, James, Sergeant, Jamie C, MacGregor, Alex J, Chipping, Jacqueline R, Marshall, Tarnya, Symmons, Deborah P M, Verstappen, Suzanne M M

“…Oral methotrexate (MTX) is the first-line therapy for patients with rheumatoid arthritis (RA). However, approximately one quarter of patients discontinue MTX…”
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Systematic review of the predictors of statin adherence for the primary prevention of cardiovascular disease by Hope, Holly F, Binkley, George M, Fenton, Sally, Kitas, George D, Verstappen, Suzanne M M, Symmons, Deborah P M

“…Previous research has shown that statin adherence for the primary prevention of CVD is lower compared to secondary prevention populations. Therefore the aim of…”
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Correction: Not all moderate disease is the same - Identification of disability trajectories among patients with rheumatoid arthritis and moderate disease activity by Pan, Yi, Norton, Sam, Gwinnutt, James M, Kearsley-Fleet, Lianne, Symmons, Deborah P M, Lunt, Mark, Young, Adam, Hyrich, Kimme L, Verstappen, Suzanne M M

“…[This corrects the article DOI: 10.1371/journal.pone.0215999.]…”
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Dyslipidaemia in rheumatoid arthritis: the role of inflammation, drugs, lifestyle and genetic factors by Toms, Tracey E, Symmons, Deborah P, Kitas, George D

“…Rheumatoid arthritis (RA) associates with excess cardiovascular morbidity and mortality, resulting in significantly shortened lifespan. Traditional risk…”
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Risk of lymphoma in patients exposed to antitumour necrosis factor therapy: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis by Mercer, Louise K, Galloway, James B, Lunt, Mark, Davies, Rebecca, Low, Audrey L S, Dixon, William G, Watson, Kath D, Symmons, Deborah P M, Hyrich, Kimme L

“…Patients with rheumatoid arthritis (RA) are at increased risk of lymphoma compared with the general population. There are concerns that tumour necrosis factor…”
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Active exercise, education, and cognitive behavioral therapy for persistent disabling low back pain : A randomized controlled trial by JOHNSON, Ruth E, JONES, Gareth T, WILES, Nicola J, CHADDOCK, Carol, POTTER, Richard G, ROBERTS, Chris, SYMMONS, Deborah P. M, WATSON, Paul J, TORGERSON, David J, MACFARLANE, Gary J

“…A randomized controlled trial. To determine 1) whether, among patients with persistent disabling low back pain (LBP), a group program of exercise and education…”
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Association Between Genetic Variation in FOXO3 and Reductions in Inflammation and Disease Activity in Inflammatory Polyarthritis by Viatte, Sebastien, Lee, James C., Fu, Bo, Espéli, Marion, Lunt, Mark, De Wolf, Jack N. E., Wheeler, Lily, Reynolds, John A., Castelino, Madhura, Symmons, Deborah P. M., Lyons, Paul A., Barton, Anne, Smith, Kenneth G. C.

“…Objective Genetic variation in FOXO3 (tagged by rs12212067) has been associated with a milder course of rheumatoid arthritis (RA) and shown to limit…”
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Risks and benefits of tumor necrosis factor-alpha inhibitors in the management of psoriatic arthritis: systematic review and metaanalysis of randomized controlled trials by SAAD, Amr A, SYMMONS, Deborah P. M, NOYCE, Peter R, ASHCROFT, Darren M

“…OBJECTIVE: To evaluate the efficacy and safety of tumor necrosis factor-alpha (TNF-alpha) inhibitors in the management of psoriatic arthritis (PsA). METHODS:…”
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Smoking is associated with the concurrent presence of multiple autoantibodies in rheumatoid arthritis rather than with anti-citrullinated protein antibodies per se: a multicenter cohort study by van Wesemael, Tineke J, Ajeganova, Sofia, Humphreys, Jennifer, Terao, Chikashi, Muhammad, Ammar, Symmons, Deborah P M, MacGregor, Alex J, Hafström, Ingiäld, Trouw, Leendert A, van der Helm-van Mil, Annette H M, Huizinga, Tom W J, Mimori, Tsuneyo, Toes, René E M, Matsuda, Fumihiko, Svensson, Björn, Verstappen, Suzanne M M, van der Woude, Diane

“…The contribution of smoking to rheumatoid arthritis (RA) is hypothesized to be mediated through formation of anti-citrullinated protein antibodies (ACPA). In…”
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Practical Management of Respiratory Comorbidities in Patients with Rheumatoid Arthritis by Bluett, James, Jani, Meghna, Symmons, Deborah P. M.

“…Lung disease is one of the most common causes of extra-articular morbidity and mortality in patients with rheumatoid arthritis (RA). Development of pulmonary…”
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Venous thrombotic events are not increased in patients with rheumatoid arthritis treated with anti-TNF therapy: results from the British Society for Rheumatology Biologics Register by Davies, Rebecca, Galloway, James B, Watson, Kath D, Lunt, Mark, Symmons, Deborah P M, Hyrich, Kimme L

“…Past studies have reported conflicting rates of venous thrombotic events (VTEs) in rheumatoid arthritis (RA). The current study aimed to compare (1) the rates…”
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Smoking‐Related Mortality in Patients With Early Rheumatoid Arthritis: A Retrospective Cohort Study Using the Clinical Practice Research Datalink by Joseph, Rebecca M., Movahedi, Mohammad, Dixon, William G., Symmons, Deborah P. M.

“…Objective To investigate the association between smoking status and smoking cessation with mortality in patients with rheumatoid arthritis (RA). Methods An…”
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Predictors of response to anti-TNF therapy in ankylosing spondylitis: results from the British Society for Rheumatology Biologics Register by Lord, Paul A. C., Farragher, Tracey M., Lunt, Mark, Watson, Kath D., Symmons, Deborah P. M., Hyrich, Kimme L.

“…Objective. Few data exist on the use of anti-TNF drugs for AS during routine clinical use in the UK. This report describes an improvement in Bath Ankylosing…”
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