Search Results - "Sykes, Cecile"

Actin dynamics, architecture, and mechanics in cell motility by Blanchoin, Laurent, Boujemaa-Paterski, Rajaa, Sykes, Cécile, Plastino, Julie

“…Tight coupling between biochemical and mechanical properties of the actin cytoskeleton drives a large range of cellular processes including polarity…”
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ATP-dependent mechanics of red blood cells by Betz, Timo, Lenz, Martin, Joanny, Jean-François, Sykes, Cécile

“…Red blood cells are amazingly deformable structures able to recover their initial shape even after large deformations as when passing through tight blood…”
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Nesprin‐2 accumulates at the front of the nucleus during confined cell migration by Davidson, Patricia M, Battistella, Aude, Déjardin, Théophile, Betz, Timo, Plastino, Julie, Borghi, Nicolas, Cadot, Bruno, Sykes, Cécile

“…The mechanisms by which cells exert forces on their nuclei to migrate through openings smaller than the nuclear diameter remain unclear. We use CRISPR/Cas9 to…”
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Mechanics of Biomimetic Liposomes Encapsulating an Actin Shell by Guevorkian, Karine, Manzi, John, Pontani, Léa-Lætitia, Brochard-Wyart, Françoise, Sykes, Cécile

“…Cell-shape changes are insured by a thin, dynamic, cortical layer of cytoskeleton underneath the plasma membrane. How this thin cortical structure impacts the…”
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F-actin mechanics control spindle centring in the mouse zygote by Chaigne, Agathe, Campillo, Clément, Voituriez, Raphaël, Gov, Nir S., Sykes, Cécile, Verlhac, Marie-Hélène, Terret, Marie-Emilie

“…Mitotic spindle position relies on interactions between astral microtubules nucleated by centrosomes and a rigid cortex. Some cells, such as mouse oocytes, do…”
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Actin polymerization or myosin contraction: two ways to build up cortical tension for symmetry breaking by Carvalho, Kevin, Lemière, Joël, Faqir, Fahima, Manzi, John, Blanchoin, Laurent, Plastino, Julie, Betz, Timo, Sykes, Cécile

“…Cells use complex biochemical pathways to drive shape changes for polarization and movement. One of these pathways is the self-assembly of actin filaments and…”
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Inferring geometrical dynamics of cell nucleus translocation by Amiri, Sirine, Zhang, Yirui, Gerardos, Andonis, Sykes, Cécile, Ronceray, Pierre

“…The ability of eukaryotic cells to squeeze through constrictions is limited by the stiffness of their large and rigid nucleus. However, migrating cells are…”
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Unexpected Membrane Dynamics Unveiled by Membrane Nanotube Extrusion by Campillo, Clément, Sens, Pierre, Köster, Darius, Pontani, Léa-Laetitia, Lévy, Daniel, Bassereau, Patricia, Nassoy, Pierre, Sykes, Cécile

“…In cell mechanics, distinguishing the respective roles of the plasma membrane and of the cytoskeleton is a challenge. The difference in the behavior of…”
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Capping protein is dispensable for polarized actin network growth and actin-based motility by Abou-Ghali, Majdouline, Kusters, Remy, Körber, Sarah, Manzi, John, Faix, Jan, Sykes, Cécile, Plastino, Julie

“…Heterodimeric capping protein (CP) binds the rapidly growing barbed ends of actin filaments and prevents the addition (or loss) of subunits. Capping activity…”
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Cell-sized liposomes reveal how actomyosin cortical tension drives shape change by Carvalho, Kevin, Tsai, Feng C., Lees, Edouard, Voituriez, Raphaël, Koenderink, Gijsje H., Sykes, Cecile

“…Animal cells actively generate contractile stress in the actin cortex, a thin actin network beneath the cell membrane, to facilitate shape changes during…”
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Adaptive Response of Actin Bundles under Mechanical Stress by Rückerl, Florian, Lenz, Martin, Betz, Timo, Manzi, John, Martiel, Jean-Louis, Safouane, Mahassine, Paterski-Boujemaa, Rajaa, Blanchoin, Laurent, Sykes, Cécile

“…Actin is one of the main components of the architecture of cells. Actin filaments form different polymer networks with versatile mechanical properties that…”
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How actin network dynamics control the onset of actin-based motility by Kawska, Agnieszka, Carvalho, Kévin, Manzi, John, Boujemaa-Paterski, Rajaa, Blanchoin, Laurent, Martiel, Jean-Louis, Sykes, Cécile

“…Cells use their dynamic actin network to control their mechanics and motility. These networks are made of branched actin filaments generated by the Arp2/3…”
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Forces Generated during Actin-Based Propulsion: A Direct Measurement by Micromanipulation by Marcy, Yann, Prost, Jacques, Carlier, Marie-France, Sykes, Cécile, Korn, Edward D.

“…Dynamic actin networks generate forces for numerous types of movements such as lamellipodia protrusion or the motion of endocytic vesicles. The actin-based…”
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Spreading Dynamics of Biomimetic Actin Cortices by Murrell, Michael, Pontani, Léa-Laetitia, Guevorkian, Karine, Cuvelier, Damien, Nassoy, Pierre, Sykes, Cécile

“…Reconstituted systems mimicking cells are interesting tools for understanding the details of cell behavior. Here, we use an experimental system that mimics…”
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Liposome adhesion generates traction stress by Murrell, Michael P., Voituriez, Raphaël, Joanny, Jean-François, Nassoy, Pierre, Sykes, Cécile, Gardel, Margaret L.

“…Mechanical forces generated by cells modulate global shape changes required for essential life processes, such as polarization, division and spreading…”
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Interplay between membrane tension and the actin cytoskeleton determines shape changes by Simon, Camille, Caorsi, Valentina, Campillo, Clément, Sykes, Cécile

“…The ability of mammalian cells to deform their membrane relies on the action of the cytoskeleton. In particular, the dynamics of the actin cytoskeleton,…”
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Cell biology Actin filaments up against a wall by Plastino, Julie, Sykes, Cécile

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Cell-sized liposomes that mimic cell motility and the cell cortex by Lemière, Joël, Carvalho, Kevin, Sykes, Cécile

“…Cells move and change shape by dynamically reorganizing their cytoskeleton next to the plasma membrane. In particular, actin assembly generates forces and…”
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Stress Release Drives Symmetry Breaking for Actin-Based Movement by van der Gucht, Jasper, Paluch, Ewa, Plastino, Julie, Sykes, Cécile, de Gennes, Pierre-Gilles

“…By using a simple assay composed of purified proteins, we studied the spontaneous polarization of actin networks polymerizing on spherical beads, which…”
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Membrane tension induces F-actin reorganization and flow in a biomimetic model cortex by Sakamoto, Ryota, Banerjee, Deb Sankar, Yadav, Vikrant, Chen, Sheng, Gardel, Margaret L., Sykes, Cecile, Banerjee, Shiladitya, Murrell, Michael P.

“…The accumulation and transmission of mechanical stresses in the cell cortex and membrane determines the mechanics of cell shape and coordinates essential…”
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