Search Results - "Sykes, Amanda K."

A Population Pharmacokinetic and Pharmacodynamic Analysis of Abemaciclib in a Phase I Clinical Trial in Cancer Patients by Tate, Sonya C., Sykes, Amanda K., Kulanthaivel, Palaniappan, Chan, Edward M., Turner, P. Kellie, Cronier, Damien M.

“…Background and Objectives Abemaciclib, a dual inhibitor of cyclin-dependent kinases 4 and 6, has demonstrated clinical activity in a number of different cancer…”
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A Randomized Phase I Study of Abemaciclib in Chinese Patients with Advanced and/or Metastatic Cancers by Zhang, Jian, Yang, Nong, Ji, Dongmei, Shen, Weina, Li, Wenhua, Han, Rubing, Wang, Ning, Tao, Haoxun, Chapman, Sonya C., Sykes, Amanda K., Zhang, Wanli, Hu, Xichun

“…Background Abemaciclib, a cyclin-dependent kinase 4 and 6 inhibitor, is approved in combination with endocrine therapy or as monotherapy for hormone…”
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A phase I study of tasisulam sodium (LY573636 sodium), a novel anticancer compound in patients with refractory solid tumors by Simon, George R., Ilaria, Robert L., Sovak, Mika A., Williams, Charles C., Haura, Eric B., Cleverly, Ann L., Sykes, Amanda K., Wagner, Margaret M., de Alwis, Dinesh P., Slapak, Christopher A., Miller, Mary A., Spriggs, David R.

“…Purpose This phase I study was carried out to determine the phase II recommended dose of tasisulam sodium (hereafter, tasisulam), a novel anticancer agent with…”
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An investigation into the roles of the major PML isoforms in HSV-1 infection by Sykes, Amanda K

“…The immediate early protein of Herpes Simplex Virus type I (HSV-1), infected cell protein zero (ICPO), has been shown to transactivate all classes of viral…”
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