Search Results - "Syed, Samreen K."

GPR142 prompts glucagon-like Peptide-1 release from islets to improve β cell function by Lin, Hua V., Wang, Jingru, Wang, Jie, Li, Weiji, Wang, Xuesong, Alston, James T., Thomas, Melissa K., Briere, Daniel A., Syed, Samreen K., Efanov, Alexander M.

“…GPR142 agonists are being pursued as novel diabetes therapies by virtue of their insulin secretagogue effects. But it is undetermined whether GPR142's…”
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BACH2 inhibition reverses β cell failure in type 2 diabetes models by Son, Jinsook, Ding, Hongxu, Farb, Thomas B, Efanov, Alexander M, Sun, Jiajun, Gore, Julie L, Syed, Samreen K, Lei, Zhigang, Wang, Qidi, Accili, Domenico, Califano, Andrea

“…Type 2 diabetes (T2D) is associated with defective insulin secretion and reduced β cell mass. Available treatments provide a temporary reprieve, but secondary…”
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Catechol estrogens stimulate insulin secretion in pancreatic β-cells via activation of the transient receptor potential A1 (TRPA1) channel by Ma, Wenzhen, Chen, Xingjuan, Cerne, Rok, Syed, Samreen K., Ficorilli, James V., Cabrera, Over, Obukhov, Alexander G., Efanov, Alexander M.

“…Estrogen hormones play an important role in controlling glucose homeostasis and pancreatic β-cell function. Despite the significance of estrogen hormones for…”
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Regulation of GPR119 receptor activity with endocannabinoid-like lipids by Syed, Samreen K, Bui, Hai Hoang, Beavers, Lisa S, Farb, Thomas B, Ficorilli, James, Chesterfield, Amy K, Kuo, Ming-Shang, Bokvist, Krister, Barrett, David G, Efanov, Alexander M

“…The GPR119 receptor plays an important role in the secretion of incretin hormones in response to nutrient consumption. We have studied the ability of an array…”
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Regulation of Endogenous (Male) Rodent GLP-1 Secretion and Human Islet Insulin Secretion by Antagonism of Somatostatin Receptor 5 by Farb, Thomas B, Adeva, Marta, Beauchamp, Thomas J, Cabrera, Over, Coates, David A, Meredith, Tamika DeShea, Droz, Brian A, Efanov, Alexander, Ficorilli, James V, Gackenheimer, Susan L, Martinez-Grau, Maria A, Molero, Victoriano, Ruano, Gema, Statnick, Michael A, Suter, Todd M, Syed, Samreen K, Toledo, Miguel A, Willard, Francis S, Zhou, Xin, Bokvist, Krister B, Barrett, David G

“…Incretin and insulin responses to nutrient loads are suppressed in persons with diabetes, resulting in decreased glycemic control. Agents including…”
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Ectonucleotidase NTPDase3 is abundant in pancreatic β-cells and regulates glucose-induced insulin secretion by Syed, Samreen K, Kauffman, Audra L, Beavers, Lisa S, Alston, James T, Farb, Thomas B, Ficorilli, James, Marcelo, Marialuisa C, Brenner, Martin B, Bokvist, Krister, Barrett, David G, Efanov, Alexander M

“…Extracellular ATP released from pancreatic β-cells acts as a potent insulinotropic agent through activation of P2 purinergic receptors. Ectonucleotidases, a…”
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Deficiency of Adiponectin Receptor 2 Reduces Diet-Induced Insulin Resistance but Promotes Type 2 Diabetes by Liu, Yanfang, Michael, M. Dodson, Kash, Shera, Bensch, William R, Monia, Brett P, Murray, Susan F, Otto, Keith A, Syed, Samreen K, Bhanot, Sanjay, Sloop, Kyle W, Sullivan, John M, Reifel-Miller, Anne

“…Adiponectin/adiponectin receptors (AdipoR) are involved in energy homeostasis and inflammatory pathways. To investigate the role of AdipoR2 in metabolic…”
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Activation of Prostaglandin E Receptor 4 Triggers Secretion of Gut Hormone Peptides GLP-1, GLP-2, and PYY by Coskun, Tamer, O'Farrell, Libbey S, Syed, Samreen K, Briere, Daniel A, Beavers, Lisa S, DuBois, Susan L, Michael, Mervyn D, Franciskovich, Jeffry B, Barrett, David G, Efanov, Alexander M

“…Prostaglandins E1 and E2 are synthesized in the intestine and mediate a range of gastrointestinal functions via activation of the prostanoid E type (EP) family…”
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Expression of 18‐wheeler in the follicle cell epithelium affects cell migration and egg morphology in Drosophila by Kleve, Cassandra D., Siler, Dominic A., Syed, Samreen K., Eldon, Elizabeth D.

“…The Drosophila ovary is a model system for examining the genetic control of epithelial morphogenesis. The somatic follicle cells form a polarized epithelium…”
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BACH2 inhibition reverses [beta] cell failure in type 2 diabetes models by Son, Jinsook, Ding, Hongxu, Farb, Thomas B, Efanov, Alexander M, Sun, Jiajun, Gore, Julie L, Syed, Samreen K, Lei, Zhigang, Wang, Qidi, Accili, Domenico, Califano, Andrea

“…Type 2 diabetes (T2D) is associated with defective insulin secretion and reduced [beta] cell mass. Available treatments provide a temporary reprieve, but…”
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Identification of biomarkers for glycaemic deterioration in type 2 diabetes by Slieker, Roderick C., Donnelly, Louise A., Akalestou, Elina, Lopez-Noriega, Livia, Melhem, Rana, Güneş, Ayşim, Abou Azar, Frederic, Efanov, Alexander, Georgiadou, Eleni, Muniangi-Muhitu, Hermine, Sheikh, Mahsa, Giordano, Giuseppe N., Åkerlund, Mikael, Ahlqvist, Emma, Ali, Ashfaq, Banasik, Karina, Brunak, Søren, Barovic, Marko, Bouland, Gerard A., Burdet, Frédéric, Canouil, Mickaël, Dragan, Iulian, Elders, Petra J. M., Fernandez, Celine, Festa, Andreas, Fitipaldi, Hugo, Froguel, Phillippe, Gudmundsdottir, Valborg, Gudnason, Vilmundur, Gerl, Mathias J., van der Heijden, Amber A., Jennings, Lori L., Hansen, Michael K., Kim, Min, Leclerc, Isabelle, Klose, Christian, Kuznetsov, Dmitry, Mansour Aly, Dina, Mehl, Florence, Marek, Diana, Melander, Olle, Niknejad, Anne, Ottosson, Filip, Pavo, Imre, Duffin, Kevin, Syed, Samreen K., Shaw, Janice L., Cabrera, Over, Pullen, Timothy J., Simons, Kai, Solimena, Michele, Suvitaival, Tommi, Wretlind, Asger, Rossing, Peter, Lyssenko, Valeriya, Legido Quigley, Cristina, Groop, Leif, Thorens, Bernard, Franks, Paul W., Lim, Gareth E., Estall, Jennifer, Ibberson, Mark, Beulens, Joline W. J., ’t Hart, Leen M, Pearson, Ewan R., Rutter, Guy A.

“…We identify biomarkers for disease progression in three type 2 diabetes cohorts encompassing 2,973 individuals across three molecular classes, metabolites,…”
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Two attacin antibacterial genes of Drosophila melanogaster by Dushay, Mitchell S., Roethele, Joseph B., Chaverri, José M., Dulek, Daniel E., Syed, Samreen K., Kitami, Toshimori, Eldon, Elizabeth D.

“…Insects express a battery of potent antimicrobial proteins in response to injury and infection. Recent work from several laboratories has demonstrated that…”
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