Search Results - "Syed, Arsalan U"

Regulation of voltage‐gated potassium channels in vascular smooth muscle during hypertension and metabolic disorders by Nieves‐Cintrón, Madeline, Syed, Arsalan U., Nystoriak, Matthew A., Navedo, Manuel F.

“…Voltage‐gated potassium (KV) channels are key regulators of vascular smooth muscle contractility and vascular tone, and thus have major influence on the…”
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Tonic regulation of middle meningeal artery diameter by ATP-sensitive potassium channels by Syed, Arsalan U, Koide, Masayo, Brayden, Joseph E, Wellman, George C

“…Activation of ATP-sensitive potassium (KATP) channels in arterial smooth muscle (ASM) contributes to vasodilation evoked by a variety of endogenous and…”
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A Gs-coupled purinergic receptor boosts Ca2+ influx and vascular contractility during diabetic hyperglycemia by Prada, Maria Paz, Syed, Arsalan U, Buonarati, Olivia R, Reddy, Gopireddy R, Nystoriak, Matthew A, Ghosh, Debapriya, Simó, Sergi, Sato, Daisuke, Sasse, Kent C, Ward, Sean M, Santana, Luis F, Xiang, Yang K, Hell, Johannes W, Nieves-Cintrón, Madeline, Navedo, Manuel F

“…Elevated glucose increases vascular reactivity by promoting L-type CaV1.2 channel (LTCC) activity by protein kinase A (PKA). Yet, how glucose activates PKA is…”
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Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Potently Dilates Middle Meningeal Arteries: Implications for Migraine by Syed, Arsalan U., Koide, Masayo, Braas, Karen M., May, Victor, Wellman, George C.

“…Migraine is a debilitating neurological disorder characterized by mild to severe headache that is often accompanied by aura and other neurological symptoms…”
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α1C S1928 Phosphorylation of CaV1.2 Channel Controls Vascular Reactivity and Blood Pressure by Flores-Tamez, Victor A, Martín-Aragón Baudel, Miguel, Hong, Junyoung, Taylor, Jade L, Ren, Lu, Le, Thanhmai, Syed, Arsalan U, Moustafa, Yumna, Singhrao, Navid, Lemus-Martinez, Wendy R, Reddy, Gopireddy R, Ramer, Victoria, Man, Kwun Nok Mimi, Bartels, Peter, Chen-Izu, Ye, Chen, Chao-Yin, Simo, Sergi, Dickson, Eamonn J, Morotti, Stefano, Grandi, Eleonora, Santana, L Fernando, Hell, Johannes W, Horne, Mary C, Nieves-Cintrón, Madeline, Navedo, Manuel F

“…Increased vascular CaV1.2 channel function causes enhanced arterial tone during hypertension. This is mediated by elevations in angiotensin II/protein kinase C…”
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AKAP5 complex facilitates purinergic modulation of vascular L-type Ca2+ channel CaV1.2 by Prada, Maria Paz, Syed, Arsalan U., Reddy, Gopireddy R., Martín-Aragón Baudel, Miguel, Flores-Tamez, Víctor A., Sasse, Kent C., Ward, Sean M., Sirish, Padmini, Chiamvimonvat, Nipavan, Bartels, Peter, Dickson, Eamonn J., Hell, Johannes W., Scott, John D., Santana, Luis F., Xiang, Yang K., Navedo, Manuel F., Nieves-Cintrón, Madeline

“…The L-type Ca 2+ channel Ca V 1.2 is essential for arterial myocyte excitability, gene expression and contraction. Elevations in extracellular glucose…”
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Onset and progression of behavioral and molecular phenotypes in a novel congenic R6/2 line exhibiting intergenerational CAG repeat stability by Cowin, Randi-Michelle, Bui, Nghiem, Graham, Deanna, Green, Jennie R, Grueninger, Stephan, Yuva-Paylor, Lisa A, Syed, Arsalan U, Weiss, Andreas, Paylor, Richard

“…In the present study we report on the use of speed congenics to generate a C57BL/6J congenic line of HD-model R6/2 mice carrying 110 CAG repeats, which…”
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Adenylyl cyclase 5-generated cAMP controls cerebral vascular reactivity during diabetic hyperglycemia by Syed, Arsalan U, Reddy, Gopireddy R, Ghosh, Debapriya, Prada, Maria Paz, Nystoriak, Matthew A, Morotti, Stefano, Grandi, Eleonora, Sirish, Padmini, Chiamvimonvat, Nipavan, Hell, Johannes W, Santana, Luis F, Xiang, Yang K, Nieves-Cintrón, Madeline, Navedo, Manuel F

“…Elevated blood glucose (hyperglycemia) is a hallmark metabolic abnormality in diabetes. Hyperglycemia is associated with protein kinase A (PKA)-mediated…”
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Impaired BKCa channel function in native vascular smooth muscle from humans with type 2 diabetes by Nieves-Cintrón, Madeline, Syed, Arsalan U., Buonarati, Olivia R., Rigor, Robert R., Nystoriak, Matthew A., Ghosh, Debapriya, Sasse, Kent C., Ward, Sean M., Santana, Luis F., Hell, Johannes W., Navedo, Manuel F.

“…Large-conductance Ca 2+ -activated potassium (BK Ca ) channels are key determinants of vascular smooth muscle excitability. Impaired BK Ca channel function…”
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α1 C S1928 Phosphorylation of Ca V 1.2 Channel Controls Vascular Reactivity and Blood Pressure by Flores-Tamez, Victor A, Martín-Aragón Baudel, Miguel, Hong, Junyoung, Taylor, Jade L, Ren, Lu, Le, Thanhmai, Syed, Arsalan U, Moustafa, Yumna, Singhrao, Navid, Lemus-Martinez, Wendy R, Reddy, Gopireddy R, Ramer, Victoria, Man, Kwun Nok Mimi, Bartels, Peter, Chen-Izu, Ye, Chen, Chao-Yin, Simo, Sergi, Dickson, Eamonn J, Morotti, Stefano, Grandi, Eleonora, Santana, L Fernando, Hell, Johannes W, Horne, Mary C, Nieves-Cintrón, Madeline, Navedo, Manuel F

“…Increased vascular Ca 1.2 channel function causes enhanced arterial tone during hypertension. This is mediated by elevations in angiotensin II/protein kinase C…”
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Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) Dilates Cerebellar Arteries Through Activation of Large-Conductance Ca2+-Activated (BK) and ATP-Sensitive (KATP) K+ Channels by Koide, Masayo, Syed, Arsalan U., Braas, Karen M., May, Victor, Wellman, George C.

“…Pituitary adenylate cyclase activating polypeptide (PACAP) is a potent vasodilator of numerous vascular beds, including cerebral arteries. Although…”
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Pituitary adenylate cyclase activating polypeptide (PACAP) dilates cerebellar arteries through activation of large-conductance Ca(2+)-activated (BK) and ATP-sensitive (K ATP) K (+) channels by Koide, Masayo, Syed, Arsalan U, Braas, Karen M, May, Victor, Wellman, George C

“…Pituitary adenylate cyclase activating polypeptide (PACAP) is a potent vasodilator of numerous vascular beds, including cerebral arteries. Although…”
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Nitric oxide synthase and reduced arterial tone contribute to arteriovenous malformation by Huang, Lawrence, Cheng, Feng, Zhang, Xuetao, Zielonka, Jacek, Nystoriak, Matthew A, Xiang, Weiwei, Raygor, Kunal, Wang, Shaoxun, Lakshmanan, Aditya, Jiang, Weiya, Yuan, Sai, Hou, Kevin S, Zhang, Jiayi, Wang, Xitao, Syed, Arsalan U, Juric, Matea, Takahashi, Takamune, Navedo, Manuel F, Wang, Rong A

“…Mechanisms underlying arteriovenous malformations (AVMs) are poorly understood. Using mice with endothelial cell (EC) expression of constitutively active…”
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Critical role for adenylyl cyclase 5 on L‐type Ca V 1.2 channel potentiation and vasoconstriction during diabetic hyperglycemia by Syed, Arsalan U, Nystoriak, Matthew A, Prada, Maria Paz, Nieves‐Cintrón, Madeline, Navedo, Manuel F

“…Abstract only Diabetes mellitus is a devastating metabolic disease affecting millions worldwide that carries with it a major risk factor of cardiovascular…”
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A PKA‐coupled purinergic receptor macromolecular complex anchored by AKAP150 potentiates L‐type Ca 2+ channel activity and vasoconstriction in diabetic hyperglycemia by Prada, Maria Paz, Syed, Arsalan U., Nystoriak, Matthew A., Patriarchi, Tommaso, Nieves‐Cintrón, Madeline, Hell, Johannes W., Navedo, Manuel F.

“…Abstract only Enhanced contractility of vascular smooth muscle in response to elevated extracellular glucose (HG), the hallmark metabolic abnormality in…”
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Local regulation of L‐type Ca V 1.2 channel and vascular reactivity by adenylyl cyclase 5 during diabetic hyperglycemia by Syed, Arsalan U., Gosh, Debapriya, Prada, Maria Paz, Reddy, Gopireddy, Nystoriak, Matthew A., Chiamvimonvat, Nipavan, Santana, Luis F., Xiang, Yang Kevin, Nieves‐Cintrón, Madeline, Navedo, Manuel F.

“…Abstract only Diabetes mellitus is a debilitating metabolic disorder affecting millions of people worldwide. One of the hallmark symptoms of diabetes is…”
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Local regulation of L‐type CaV1.2 channel and vascular reactivity by adenylyl cyclase 5 during diabetic hyperglycemia by Syed, Arsalan U., Gosh, Debapriya, Prada, Maria Paz, Reddy, Gopireddy, Nystoriak, Matthew A., Chiamvimonvat, Nipavan, Santana, Luis F., Xiang, Yang Kevin, Nieves‐Cintrón, Madeline, Navedo, Manuel F.

“…Diabetes mellitus is a debilitating metabolic disorder affecting millions of people worldwide. One of the hallmark symptoms of diabetes is hyperglycemia…”
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Mechanism of Pituitary Adenylate Cyclase Activating Polypeptide (PACAP)‐Induced Dilation of Middle Meningeal Artery: Role of ATP‐Sensitive Potassium (K ATP ) Channels by Syed, Arsalan U., Koide, Masayo, May, Victor, Wellman, George C.

“…Abstract only Migraine is a complex neurological condition that presents as intense episodic unilateral headaches accompanied by nausea, photophobia,…”
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Anchored G s ‐coupled purinergic receptor regulation of L‐type Ca V 1.2 and vascular tone in diabetic hyperglycemia by Prada, Maria Paz, Syed, Arsalan U., Buonarati, Olivia R., Ghosh, Debapriya, Nystoriak, Matthew A., Reddy, Gopireddy Raghu, Sasse, Kent C., Ward, Sean M., Xiang, Y. Kevin, Santana, Luis F., Nieves‐Cintrón, Madeline, Hell, Johannes W., Navedo, Manuel F.

“…Abstract only Enhanced arterial myocyte contractility in response to elevated extracellular glucose (hyperglycemia) has been associated with protein kinase A…”
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Anchored Gs‐coupled purinergic receptor regulation of L‐type CaV1.2 and vascular tone in diabetic hyperglycemia by Prada, Maria Paz, Syed, Arsalan U., Buonarati, Olivia R., Ghosh, Debapriya, Nystoriak, Matthew A., Reddy, Gopireddy Raghu, Sasse, Kent C., Ward, Sean M., Xiang, Y. Kevin, Santana, Luis F., Nieves‐Cintrón, Madeline, Hell, Johannes W., Navedo, Manuel F.

“…Enhanced arterial myocyte contractility in response to elevated extracellular glucose (hyperglycemia) has been associated with protein kinase A (PKA) dependent…”
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