Search Results - "Sychev, D.A."

Molecular genetic predictors of the efficacy and safety of tamsulosin therapy by Abdullaev, S P, Shatokhin, M N, Teodorovich, O V, Sychev, D A

“…Individual differences in efficacy and safety of drugs between patients are a significant problem in modern pharmacotherapy. The bodys pharmacological response…”
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Effects of CYP2D6 activity on the efficacy and safety of mirtazapine in patients with depressive disorders and comorbid alcohol use disorder by Zastrozhin, M S, Skryabin, V Y, Smirnov, V V, Grishina, E A, Ryzhikova, K A, Chumakov, E M, Bryun, E A, Sychev, D A

“…The objective of the study was to investigate the effects of CYP2D6 activity on the efficacy and safety of mirtazapine in patients with depressive disorders…”
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Gene Polymorphism C3435T For ABCB1 and Antihypertensive Efficacy, Safety of The Amlodipine At The Russians Hypertensive Patients by Sychev, D.A, Shih, N.V, Grishina, E.A, Ryzhikova, K.A, Morozova, T.E

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Adverse drug reactions of macrolide therapy: analysis of spontaneous reports according to the Pharmacovigilance system by Skryabina, A.A., Nikiforov, V.V., Shakhmardanov, M.Z., Zastrozhin, M.S., Skryabin, V.Yu, Sychev, D.A.

“…Objective. To perform pharmacoepidemiological analysis of spontaneous reports of adverse drug reactions (ADRs) occurred during macrolide group antibiotics…”
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The Association of the rs2108622 Single Nucleotide Polymorphism in the CYP4F2 Gene with Resistance to Clopidogrel by Konova, O.D, Mirzaev, K.B, Ryzhikova, K.A, Sozaeva, Zh.A, Andreev, D.A, Sychev, D.A

“…The aim of the study was to determine the impact of carriership of at least one CYP4F2*3 allele on the risk of resistance to clopidogrel in patients with acute…”
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Assessment of CYP2C19, ABCB1, CYP3A5 Genes Polymorphisms’ and CYP3A4 Isoenzyme Activity Influence on Major Adverse Cardiovascular Events Among Patients with an Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention by Rytkin, E, Mirzaev, K.B, Smirnov, V.V, Ryzhikova, K.A, Sozaeva, Zh.A, Andreev, D.A, Sychev, D.A

“…Background The aim of this study was to determine the impact of CYP2C19, ABCB1, CYP3A5 genes polymorphisms and CYP3A4 isoenzyme activity on clopidogrel…”
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Effect of Pharmacogenetic-Based Dosing of Warfarin on Bleeding During Anticoagulation in Russian Patients: A Systematic Review and Meta-Analysis by Ivashchenko, D.V, Rusin, I.V, Sychev, D.A

“…To summarize the current evidence supporting the use of genetic testing before prescribing warfarin, we performed a meta-analysis of Russian prospective…”
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The Frequency of Cyp2c19 Genetic Polymorphisms In Russian Patients With Peptic Ulcer Treated With Proton Pump Inhibitors by Denisenko, N.P, Sychev, D.A, Sizova, Zh.M, Grachev, A.V, Velikolug, K.A

“…Conclusion There is a high frequency of CYP2C19 genotypes associated with modified response on proton pump inhibitors in Russian patients with peptic ulcer…”
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Possibilities of optimization of statin Therapy based on genotyping SLCO1B1 and CYP2C9 at patients with Cardiovascular disease by Sirotkina, A.M, Khokhlov, A.A, Voronina, E.A, Sychev, D.A

“…The aim was to determine the frequency of polymorphism of SLCO1B1, frequency of polymorphisms of CYP2C9*2/*3 in carriers of C allele of the gene SLCO1B1 in…”
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Impact of the CYP3A4 metabolic activity and CYP2C19 Polymorphisms on Antiplatelet effects of clopidogrel in Russian Patients with acute Coronary Syndrome undergoing coronary stent implantation by Mirzaev, K.B, Sychev, D.A, Andreev, D.A, Kazakov, R.E, Smirnov, V.V

“…Material and Methods We determined the CYP2C19 genotypes (Real-time PCR) and CYP3A4 metabolic activity (6b-hydroxycortisol/cortisol (6-OHC/FC) in urine were…”
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A Case report of suicide in a teenager with long-term use of fluoxetine associated with CYP2D6 Polymorphism by Asriyants, S.V, Veselkina, O.V, Sychev, D.A, Obuhova, Y.D, Polyakov, A.V, Klevno, V.A

“…Conclusions Fluoxetine use may cause toxic drug accumulation thus leading to worsening of suicidal thoughts if taken by teenagers with possible genetic…”
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The Impact of Cyp4f2 Polymorphism on The Safety Profile And Regime Dosing of Phenindion In Patients With Valvular Atrial Fibrillation by Shakhidzhanova, V.S, Sychev, D.A, Kazаkov, R.E, Grishenko, N.D, Palamarchuk, Y.Y, Kossovskaya, A.V, Tretyakov, A.Y

“…Introduction In the reason of FDA prohibition in using of "new" oral anticoagulants, vitamin K antagonists have become uncontested drugs to the patients with…”
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THE IDENTIFICATION OF THE PARAMETERS OF POWER ELECTRICAL EQUIPMENT FOR PIPE COLD ROLLING MILLS by Sychev, D.A., Kushnarev, V.A., Grigorev, M.A., Bukhtoyarov, V.F., Tulegenov, E.M.

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Lattice Study of the Equation of State of a Rotating Gluon Plasma by Braguta, V. V., Kudrov, I. E., Roenko, A. A., Sychev, D. A., Chernodub, M. N.

“…The effect of uniform rotation on the equation of state of gluodynamics has been studied in lattice simulation. To this end, the system has been considered in…”
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OPTIMIZATION OF ELECTRIC DRIVES OF INDUSTRIAL MECHANISMS by Khriukin, D.Yu, Tulegenov, E.M., Semenova, K.D., Kushnarev, V.A., Sychev, D.A.

“…This article discusses optimization problems in the design of an AC electric drive kit with a capacity of up to 1 MW. The need for optimization in the design…”
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Eacpt-0009 - Effect of Pharmacogenetic-Based Dosing of Warfarin on Bleeding During Anticoagulation in Russian Patients: A Systematic Review and Meta-Analysis by Ivashchenko, D.V., Rusin, I.V., Sychev, D.A.

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Influence of Relativistic Rotation on QCD Properties by Braguta, V. V., Chernodub, M. N., Kudrov, I. E., Roenko, A. A., Sychev, D. A.

“…This paper is devoted to the study of QCD properties affected by relativistic rotation. The presented results were obtained within the first-principle lattice…”
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Effects of plasma concentration of micro-RNA Mir-27b and CYP3A422 on equilibrium concentration of alprazolam in patients with anxiety disorders comorbid with alcohol use disorder by Zastrozhin, M.S., Skryabin, V.Yu, Smirnov, V.V., Petukhov, A.E., Pankratenko, E.P., Zastrozhina, A.K., Grishina, E.A., Ryzhikova, K.A., Bure, I.V., Golovinskii, P.A., Koporov, S.G., Bryun, E.A., Sychev, D.A.

“…•We examined a total of 105 patients with anxiety disorders comorbid with AUD.•Therapy included alprazolam, and its efficacy and safety profiles were…”
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Antibiotic therapy under polypragmatic conditions: a course to safety by Sychev, Igor N., Fedina, L.V., Sychev, Dmitriy A.

“…Prescribing safe and effective drug therapy is becoming increasingly challenging. Recently, there has been an upward trend in the number of patients…”
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Data processing center of RadioAstron space VLBI project by Shatskaya, M.V., Abramov, A.A., Fedorov, N.A., Kostenko, V.I., Likhachev, S.F., Seliverstov, S.I., Sychev, D.A.

“…In this paper, questions on development, implementation, and operation of RadioAstron project Data Processing Center (DPC) are reviewed. The main components of…”
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