Search Results - "Sy, M S"

Binding of pro-prion to filamin A: by design or an unfortunate blunder by Li, C, Xin, W, Sy, M-S

“…Over the last decades, cancer research has focused on tumor suppressor genes and oncogenes. Genes in other cellular pathways has received less attention…”
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Mucosal vaccination delays or prevents prion infection via an oral route by Goñi, F., Knudsen, E., Schreiber, F., Scholtzova, H., Pankiewicz, J., Carp, R., Meeker, H.C., Rubenstein, R., Brown, D.R., Sy, M.-S., Chabalgoity, J.A., Sigurdsson, E.M., Wisniewski, T.

“…In recent years major outbreaks of prion disease linked to oral exposure of the prion agent have occurred in animal and human populations. These disorders are…”
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Deficiency of Transporter for Antigen Presentation (TAP) in Tumor Cells Allows Evasion of Immune Surveillance and Increases Tumorigenesis by Johnsen, A. K, Templeton, D. J, Sy, M.-S, Harding, C. V

“…Proteins involved in class I MHC (MHC-I) Ag processing, such as the TAP, are deficient in some human tumor cells. This suggests that antitumor responses by CD8…”
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Human defensin 5 expression in intestinal metaplasia of the upper gastrointestinal tract by Shen, B, Porter, E M, Reynoso, E, Shen, C, Ghosh, D, Connor, J T, Drazba, J, Rho, H K, Gramlich, T L, Li, R, Ormsby, A H, Sy, M-S, Ganz, T, Bevins, C L

“…Background: Upper gastrointestinal tract intestinal metaplasia (IM) is termed Barrett’s oesophagus (BO) or gastric intestinal metaplasia (GIM), depending on…”
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Expression of Hyaluronidase by Tumor Cells Induces Angiogenesis in vivo by Liu, Dacai, Pearlman, Eric, Diaconu, Eugenia, Guo, Kun, Mori, Hiroshi, Haqqi, Tariq, Markowitz, Sanford, Willson, James, Sy, Man-Sun

“…Hyaluronic acid is a proteoglycan present in the extracellular matrix and is important for the maintenance of tissue architecture. Depolymerization of…”
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Aberrant metal binding by prion protein in human prion disease by Wong, Boon‐Seng, Chen, Shu G., Colucci, Monica, Xie, Zhiliang, Pan, Tao, Liu, Tong, Li, Ruliang, Gambetti, Pierluigi, Sy, Man‐Sun, Brown, David R.

“…Human prion diseases are characterized by the conversion of the normal prion protein (PrPC) into a pathogenic isomer (PrPSc). Distinct PrPSc conformers are…”
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Oxidative impairment in scrapie‐infected mice is associated with brain metals perturbations and altered antioxidant activities by Wong, Boon‐Seng, Brown, David R., Pan, Tao, Whiteman, Matthew, Liu, Tong, Bu, Xiaodong, Li, Ruliang, Gambetti, Pierluigi, Olesik, John, Rubenstein, Richard, Sy, Man‐Sun

“…Prion diseases are characterized by the conversion of the normal cellular prion protein (PrPC) into a pathogenic isoform (PrPSc). PrPC binds copper, has…”
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Effect of the E200K Mutation on Prion Protein Metabolism : Comparative Study of a Cell Model and Human Brain by Capellari, Sabina, Parchi, Piero, Russo, Claudio M, Sanford, Jeremy, Sy, Man-Sun, Gambetti, Pierluigi, Petersen, Robert B

“…The hallmark of prion diseases is the cerebral accumulation of a conformationally altered isoform (PrP(Sc)) of a normal cellular protein, the prion protein…”
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Antibodies to intercellular adhesion molecule 1/lymphocyte function-associated antigen 1 prevent crescent formation in rat autoimmune glomerulonephritis by NISHIKAWA, K, GUO, Y.-J, MIYASAKA, M, TAMATANI, T, COLLINS, A. B, SY, M.-S, MCCLUSKEY, R. T, ANDRES, G

“…In patients with glomerulonephritis widespread crescents are associated with a poor prognosis. Crescent formation appears to depend on the migration of…”
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The winged helix/forkhead transcription factor Foxq1 regulates differentiation of hair in satin mice by Hong, Hee-Kyung, Noveroske, Janice K., Headon, Denis J., Liu, Tong, Sy, Man-Sun, Justice, Monica J., Chakravarti, Aravinda

“…Satin (sa) homozygous mice have a silky coat with high sheen arising from structurally abnormal medulla cells and defects in differentiation of the hair shaft…”
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Mapping the antigenicity of copper-treated cellular prion protein with the scrapie isoform by Wong, B-S, Li, R, Sassoon, J, Kang, S-C, Liu, T, Pan, T, Greenspan, N S, Wisniewski, T, Brown, D R, Sy, M-S

“…When recombinant and cellular prion protein (PrP(C)) binds copper, it acquires properties resembling the scrapie isoform (PrP(Sc)), namely protease resistance,…”
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Phorbol myristate acetate stimulates the dimerization of CD44 involving a cysteine in the transmembrane domain by Liu, D, Sy, MS

“…Receptor oligomerization is important for ligand binding and signal transduction. CD44 is a transmembrane protein present on many cell types. One of the…”
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The ubiquitin specific protease USP34 promotes ubiquitin signaling at DNA double-strand breaks by Sy, Shirley M H, Jiang, Jun, O, Wai Sum, Deng, Yiqun, Huen, Michael S Y

“…Ubiquitylation plays key roles in DNA damage signal transduction. The current model envisions that lysine63-linked ubiquitin chains, via the concerted action…”
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Identification of a costimulatory molecule rapidly induced by CD40L as CD44H by Guo, Y, Wu, Y, Shinde, S, Sy, M S, Aruffo, A, Liu, Y

“…The interaction between CD40 ligand and CD40 is critical for activation of T and B cells in vivo. We have recently demonstrated that this interaction rapidly…”
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Down-regulation of the transporter for antigen presentation, proteasome subunits, and class I major histocompatibility complex in tumor cell lines by JOHNSEN, A, FRANCE, J, SY, M.-S, HARDING, C. V

“…Tumor cells may alter the expression of proteins involved in antigen processing and presentation, allowing them to avoid recognition and elimination by…”
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A New Human Prostate Carcinoma Cell Line, 22Rv1 by R. Michael Sramkoski, Pretlow, Thomas G., Joseph M. Giaconia, Pretlow, Theresa P., Schwartz, Stuart, Sy, Man-Sun, Susan R. Marengo, Rhim, Johng S., Desheng Zhang, James W. Jacobberger

“…A cell line has been derived from a human prostatic carcinoma xenograft, CWR22R. This represents one of very few available cell lines representative of this…”
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Distinct effects of two CD44 isoforms on tumor growth in vivo by MAN SUN SY, YA-JUN GUO, STAMENKOVIC, I

“…Tumor growth is dependent in part on interactions between tumor cells and the extracellular matrix of host tissues. Expression of the cell surface glycoprotein…”
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The role of antigen-presenting B cells in T cell priming in vivo. Studies of B cell-deficient mice by Kurt-Jones, EA, Liano, D, HayGlass, KA, Benacerraf, B, Sy, MS, Abbas, AK

“…Mice rendered B cell deficient by treatment with rabbit anti-mouse IgM (anti-mu) antibodies from birth fail to respond when primed with soluble protein…”
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Expression and Structural Characterization of the Recombinant Human Doppel Protein by Lu, Ke, Wang, Wen, Xie, Zhiliang, Wong, Boon-Seng, Li, Ruliang, Petersen, Robert B, Sy, Man-Sun, Chen, Shu G

“…The doppel protein (Dpl) is a newly recognized prion protein (PrP)-like molecule encoded by a novel gene locus, prnd, located on the same chromosome as the PrP…”
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Cellular prion protein is expressed on peripheral blood mononuclear cells but not platelets of normal and scrapie-infected sheep by Herrmann, LM, Davis, WC, Knowles, DP, Wardrop, KJ, Sy, MS, Gambetti, P, O' Rourke, KI

“…United States Department of Agriculture, Agricultural Research Service, Animal Disease Research Unit, 3003 ADBF, Washington State University, Pullman, WA…”
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