Search Results - "Swords, W."
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An updated conceptual model on the pathogenesis of bacterial vaginosis
Published in The Journal of infectious diseases (01-11-2019)“…Bacterial vaginosis (BV) is the most common cause of vaginal discharge. It is associated with an increased risk of preterm delivery, pelvic inflammatory…”
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Cooperativity between Stenotrophomonas maltophilia and Pseudomonas aeruginosa during Polymicrobial Airway Infections
Published in Infection and immunity (23-03-2020)“…is a Gram-negative bacterium found ubiquitously in the environment that has historically been regarded as nonpathogenic. is increasingly observed in patient…”
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Comparative genomics of clinical Stenotrophomonas maltophilia isolates reveals genetic diversity which correlates with colonization and persistence in vivo
Published in Microbiology (Society for General Microbiology) (01-11-2023)“…is a Gram-negative emerging opportunistic pathogen often present in people with respiratory diseases such as cystic fibrosis (CF). People with CF (pwCF)…”
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PD-L2 Regulates B-1 Cell Antibody Production against Phosphorylcholine through an IL-5-Dependent Mechanism
Published in The Journal of immunology (1950) (15-09-2017)“…B-1 cells produce natural Abs which provide an integral first line of defense against pathogens while also performing important homeostatic housekeeping…”
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Acute polymicrobial airway infections: analysis in cystic fibrosis mice
Published in Microbiology (Society for General Microbiology) (01-01-2023)“…Cystic fibrosis (CF) is a genetic disorder affecting epithelial ion transport, which among other impacts results in defective mucociliary clearance and innate…”
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Haemophilus parainfluenzae Strain ATCC 33392 Forms Biofilms In Vitro and during Experimental Otitis Media Infections
Published in Infection and immunity (01-09-2017)“…is a nutritionally fastidious, Gram-negative bacterium with an oropharyngeal/nasopharyngeal carriage niche that is associated with a range of opportunistic…”
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Nontypeable Haemophilus influenzae Infection Impedes Pseudomonas aeruginosa Colonization and Persistence in Mouse Respiratory Tract
Published in Infection and immunity (17-02-2022)“…Patients with cystic fibrosis (CF) experience lifelong respiratory infections, which are a significant cause of morbidity and death. These infections are…”
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Pathogenesis of Achromobacter xylosoxidans respiratory infections: colonization, persistence, and transcriptome profiling in synthetic cystic fibrosis sputum medium
Published in Infection and immunity (12-12-2023)“…Cystic fibrosis (CF) is a genetic disease affecting epithelial ion transport, resulting in thickened mucus and impaired mucociliary clearance. Persons with CF…”
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Nontypeable Haemophilus influenzae biofilms: role in chronic airway infections
Published in Frontiers in cellular and infection microbiology (2012)“…Like many pathogens inhabiting mucosal surfaces, nontypeable Haemophilus influenzae (NTHi) forms multicellular biofilm communities both in vitro and in various…”
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Editorial: Otitis media susceptibility due to genetic variants
Published in Frontiers in genetics (2023)Get full text
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Capsular Polysaccharide Interferes with Biofilm Formation by Pasteurella multocida Serogroup A
Published in mBio (21-11-2017)“…is an important multihost animal and zoonotic pathogen that is capable of causing respiratory and multisystemic diseases, bacteremia, and bite wound…”
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Indirect pathogenicity of Haemophilus influenzae and Moraxella catarrhalis in polymicrobial otitis media occurs via interspecies quorum signaling
Published in mBio (06-07-2010)“…Otitis media (OM) is among the leading diseases of childhood and is caused by opportunists that reside within the nasopharynx, such as Haemophilus influenzae…”
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Autoinducer 2 (AI-2) Production by Nontypeable Haemophilus influenzae 86-028NP Promotes Expression of a Predicted Glycosyltransferase That Is a Determinant of Biofilm Maturation, Prevention of Dispersal, and Persistence In Vivo
Published in Infection and immunity (01-12-2018)“…Nontypeable (NT ) is an extremely common human pathobiont that persists on the airway mucosal surface within biofilm communities, and our previous work has…”
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Nontypeable Haemophilus influenzae Initiates Formation of Neutrophil Extracellular Traps
Published in Infection and Immunity (01-01-2011)“…Nontypeable Haemophilus influenzae (NTHI) is a leading cause of otitis media infections, which are often chronic and/or recurrent in nature. NTHI and other…”
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Hyperencapsulated mucoid pneumococcal isolates from patients with cystic fibrosis have increased biofilm density and persistence in vivo
Published in Pathogens and disease (01-10-2018)“…Mucoid bacteria, predominately Pseudomonas aeruginosa, are commonly associated with decline in pulmonary function in children with cystic fibrosis (CF), and…”
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Residence of Streptococcus pneumoniae and Moraxella catarrhalis within polymicrobial biofilm promotes antibiotic resistance and bacterial persistence in vivo
Published in Pathogens and disease (01-04-2014)“…Abstract Otitis media (OM) is an extremely common pediatric ailment caused by opportunists that reside within the nasopharynx. Inflammation within the upper…”
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Dual pili post-translational modifications synergize to mediate meningococcal adherence to platelet activating factor receptor on human airway cells
Published in PLoS pathogens (01-05-2013)“…Pili of pathogenic Neisseria are major virulence factors associated with adhesion, twitching motility, auto-aggregation, and DNA transformation. Pili of N…”
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Coinfection with Haemophilus influenzae Promotes Pneumococcal Biofilm Formation during Experimental Otitis Media and Impedes the Progression of Pneumococcal Disease
Published in The Journal of infectious diseases (01-10-2010)“…Background. Otitis media is an extremely common pediatric infection and is mostly caused by bacteria that are carried within the nasopharyngeal microbiota. It…”
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Nontypeable Haemophilus influenzae Redox Recycling of Protein Thiols Promotes Resistance to Oxidative Killing and Bacterial Survival in Biofilms in a Smoke-Related Infection Model
Published in mSphere (23-02-2022)“…Smoke exposure is a risk factor for community-acquired pneumonia, which is typically caused by host-adapted airway opportunists like nontypeable Haemophilus…”
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Pneumococcal Phasevarions Control Multiple Virulence Traits, Including Vaccine Candidate Expression
Published in Microbiology spectrum (01-06-2022)“…Streptococcus pneumoniae is the most common cause of bacterial illness worldwide. Current vaccines based on the polysaccharide capsule are only effective…”
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