Search Results - "Sworder, Brian J"

Predicting HLA class II antigen presentation through integrated deep learning by Chen, Binbin, Khodadoust, Michael S., Olsson, Niclas, Wagar, Lisa E., Fast, Ethan, Liu, Chih Long, Muftuoglu, Yagmur, Sworder, Brian J., Diehn, Maximilian, Levy, Ronald, Davis, Mark M., Elias, Joshua E., Altman, Russ B., Alizadeh, Ash A.

“…Accurate prediction of antigen presentation by human leukocyte antigen (HLA) class II molecules would be valuable for vaccine development and cancer…”
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The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma by Steen, Chloé B., Luca, Bogdan A., Esfahani, Mohammad S., Azizi, Armon, Sworder, Brian J., Nabet, Barzin Y., Kurtz, David M., Liu, Chih Long, Khameneh, Farnaz, Advani, Ranjana H., Natkunam, Yasodha, Myklebust, June H., Diehn, Maximilian, Gentles, Andrew J., Newman, Aaron M., Alizadeh, Ash A.

“…Biological heterogeneity in diffuse large B cell lymphoma (DLBCL) is partly driven by cell-of-origin subtypes and associated genomic lesions, but also by…”
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Secreted frizzled related-protein 2 (Sfrp2) deficiency decreases adult skeletal stem cell function in mice by de Castro, Luis Fernandez, Sworder, Brian J, Mui, Byron, Futrega, Kathryn, Berendsen, Agnes, Phillips, Matthew D, Burbach, Nathan J, Cherman, Natasha, Kuznetsov, Sergei, Gabet, Yankel, Holmbeck, Kenn, Robey, Pamela G

“…In a previous transcriptomic study of human bone marrow stromal cells (BMSCs, also known as bone marrow-derived "mesenchymal stem cells"), SFRP2 was highly…”
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Molecular profile of clonal strains of human skeletal stem/progenitor cells with different potencies by Sworder, Brian J., Yoshizawa, Sayuri, Mishra, Prasun J., Cherman, Natasha, Kuznetsov, Sergei A., Merlino, Glenn, Balakumaran, Arun, Robey, Pamela G.

“…Bone marrow stromal cells (BMSCs, also known as bone marrow-derived mesenchymal stem cells) are fibroblastic reticular cells, a subset of which is composed of…”
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Enhanced detection of minimal residual disease by targeted sequencing of phased variants in circulating tumor DNA by Kurtz, David M., Soo, Joanne, Co Ting Keh, Lyron, Alig, Stefan, Chabon, Jacob J., Sworder, Brian J., Schultz, Andre, Jin, Michael C., Scherer, Florian, Garofalo, Andrea, Macaulay, Charles W., Hamilton, Emily G., Chen, Binbin, Olsen, Mari, Schroers-Martin, Joseph G., Craig, Alexander F. M., Moding, Everett J., Esfahani, Mohammad S., Liu, Chih Long, Dührsen, Ulrich, Hüttmann, Andreas, Casasnovas, René-Olivier, Westin, Jason R., Roschewski, Mark, Wilson, Wyndham H., Gaidano, Gianluca, Rossi, Davide, Diehn, Maximilian, Alizadeh, Ash A.

“…Circulating tumor-derived DNA (ctDNA) is an emerging biomarker for many cancers, but the limited sensitivity of current detection methods reduces its utility…”
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Cell-free DNA in large B-cell lymphoma: MRD and beyond by Sworder, Brian J., Kurtz, David M.

“…Large B-cell lymphomas (LBCLs) are a strikingly diverse set of diseases, including clinical, biological, and molecular heterogeneity. Despite a wealth of…”
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Inferring gene expression from cell-free DNA fragmentation profiles by Esfahani, Mohammad Shahrokh, Hamilton, Emily G., Mehrmohamadi, Mahya, Nabet, Barzin Y., Alig, Stefan K., King, Daniel A., Steen, Chloé B., Macaulay, Charles W., Schultz, Andre, Nesselbush, Monica C., Soo, Joanne, Schroers-Martin, Joseph G., Chen, Binbin, Binkley, Michael S., Stehr, Henning, Chabon, Jacob J., Sworder, Brian J., Hui, Angela B-Y, Frank, Matthew J., Moding, Everett J., Liu, Chih Long, Newman, Aaron M., Isbell, James M., Rudin, Charles M., Li, Bob T., Kurtz, David M., Diehn, Maximilian, Alizadeh, Ash A.

“…Profiling of circulating tumor DNA (ctDNA) in the bloodstream shows promise for noninvasive cancer detection. Chromatin fragmentation features have previously…”
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Determinants of resistance to engineered T cell therapies targeting CD19 in large B cell lymphomas by Sworder, Brian J., Kurtz, David M., Alig, Stefan K., Frank, Matthew J., Shukla, Navika, Garofalo, Andrea, Macaulay, Charles W., Shahrokh Esfahani, Mohammad, Olsen, Mari N., Hamilton, James, Hosoya, Hitomi, Hamilton, Mark, Spiegel, Jay Y., Baird, John H., Sugio, Takeshi, Carleton, Mia, Craig, Alexander F.M., Younes, Sheren F., Sahaf, Bita, Sheybani, Natasha D., Schroers-Martin, Joseph G., Liu, Chih Long, Oak, Jean S., Jin, Michael C., Beygi, Sara, Hüttmann, Andreas, Hanoun, Christine, Dührsen, Ulrich, Westin, Jason R., Khodadoust, Michael S., Natkunam, Yasodha, Majzner, Robbie G., Mackall, Crystal L., Diehn, Maximilian, Miklos, David B., Alizadeh, Ash A.

“…Most relapsed/refractory large B cell lymphoma (r/rLBCL) patients receiving anti-CD19 chimeric antigen receptor (CAR19) T cells relapse. To characterize…”
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Short Diagnosis-to-Treatment Interval Is Associated With Higher Circulating Tumor DNA Levels in Diffuse Large B-Cell Lymphoma by Alig, Stefan, Macaulay, Charles W, Kurtz, David M, Dührsen, Ulrich, Hüttmann, Andreas, Schmitz, Christine, Jin, Michael C, Sworder, Brian J, Garofalo, Andrea, Shahrokh Esfahani, Mohammad, Nabet, Barzin Y, Soo, Joanne, Scherer, Florian, Craig, Alexander F M, Casasnovas, Olivier, Westin, Jason R, Gaidano, Gianluca, Rossi, Davide, Roschewski, Mark, Wilson, Wyndham H, Meignan, Michel, Diehn, Maximilian, Alizadeh, Ash A

“…Patients with Diffuse Large B-cell Lymphoma (DLBCL) in need of immediate therapy are largely under-represented in clinical trials. The diagnosis-to-treatment…”
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A human lymphoma organoid model for evaluating and targeting the follicular lymphoma tumor immune microenvironment by Kastenschmidt, Jenna M, Schroers-Martin, Joseph G, Sworder, Brian J, Sureshchandra, Suhas, Khodadoust, Michael S, Liu, Chih Long, Olsen, Mari, Kurtz, David M, Diehn, Maximilian, Wagar, Lisa E, Alizadeh, Ash A

“…Heterogeneity in the tumor microenvironment (TME) of follicular lymphomas (FLs) can affect clinical outcomes. Current immunotherapeutic strategies, including…”
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Tracing Founder Mutations in Circulating and Tissue-Resident Follicular Lymphoma Precursors by Schroers-Martin, Joseph G, Soo, Joanne, Brisou, Gabriel, Scherer, Florian, Kurtz, David M, Sworder, Brian J, Khodadoust, Michael S, Jin, Michael C, Bru, Agnès, Liu, Chih Long, Stehr, Henning, Vineis, Paolo, Natkunam, Yasodha, Teras, Lauren R, Song, Joo Y, Nadel, Bertrand, Diehn, Maximilian, Roulland, Sandrine, Alizadeh, Ash A

“…Follicular lymphomas (FL) are characterized by BCL2 translocations, often detectable in blood years before FL diagnosis, but also observed in aging healthy…”
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Bone marrow skeletal stem/progenitor cell defects in dyskeratosis congenita and telomere biology disorders by Balakumaran, Arun, Mishra, Prasun J., Pawelczyk, Edyta, Yoshizawa, Sayuri, Sworder, Brian J., Cherman, Natasha, Kuznetsov, Sergei A., Bianco, Paolo, Giri, Neelam, Savage, Sharon A., Merlino, Glenn, Dumitriu, Bogdan, Dunbar, Cynthia E., Young, Neal S., Alter, Blanche P., Robey, Pamela G.

“…Dyskeratosis congenita (DC) is an inherited multisystem disorder, characterized by oral leukoplakia, nail dystrophy, and abnormal skin pigmentation, as well as…”
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Specificity of immunoglobulin high-throughput sequencing minimal residual disease monitoring in non-Hodgkin lymphomas by Shukla, Navika D., Schroers-Martin, Joseph G., Sworder, Brian J., Kathuria, Karan Raj, Alig, Stefan K., Frank, Matthew J., Miklos, David B., Coutre, Steven, Diehn, Maximilian, Khodadoust, Michael S., Roschewski, Mark, Kurtz, David M., Alizadeh, Ash A.

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Corrigendum to “Molecular profile of clonal strains of human skeletal stem/progenitor cells with different potencies” [stem cell res. 14 (2015) 297–306] by Sworder, Brian J., Yoshizawa, Sayuri, Mishra, Prasun J., Cherman, Natasha, Kuznetsov, Sergei A., Merlino, Glenn, Balakumaran, Arun, Robey, Pamela G.

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Development of Circulating Tumor DNA (ctDNA) for Molecular Measurable Residual Disease (MRD) in Acute Myeloid Leukemia (AML) by Gunaratne, Ruwan, Zhou, Crystal, Tai, Jesse W., Schwede, Matthew, Tanaka, Kailee, Alkaitis, Matthew, Yin, Raymond, Sworder, Brian J., Mannis, Gabriel, Majeti, Ravindra, Khodadoust, Michael S., Kurtz, David M., Zhang, Tian Y.

“…Introduction: Despite advances in therapeutic options, the majority of AML patients experience relapsed or refractory disease. Standard-of-care (SOC) methods…”
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End-of-Treatment Response Assessment after Frontline Therapy for Aggressive B-Cell Lymphoma: Landmark Comparison of a Singular PET/CT Scan Versus Ultrasensitive Circulating Tumor DNA by Roschewski, Mark, Lindenberg, Liza, Mena, Esther, Lakhotia, Rahul, Melani, Christopher, Steinberg, Seth M., Schultz, Andre, Hogan, Gregory, Chabon, Jake J., Close, Sandra, Diehn, Maximilian, Sworder, Brian J., Kurtz, David M., Alizadeh, Ash A., Wilson, Wyndham H.

“…Background : Lymphoma response criteria rely on PET/CT scans at end of therapy (EOT) to determine complete response (CR), which is necessary for cure. ~25% of…”
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Prognostic Utility of Minimal Residual Disease (MRD) after Curative Intent Induction Therapy for DLBCL: A Prospective Real-World Ctdna Study by Sworder, Brian J., Yoon, Sang Eun, Kim, Seok Jin, Schultz, Andre, Hogan, Gregory, Close, Sandra, Chabon, Jacob J., Diehn, Maximilian, Kurtz, David M., Alizadeh, Ash A., Kim, Won Seog

“…Background: The prognostic value of MRD using ultra-sensitive ctDNA assays after 1L DLBCL immunochemotherapy was recently reported (Roschewski, ASH 2022)…”
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Distinct Hodgkin lymphoma subtypes defined by noninvasive genomic profiling by Alig, Stefan K., Shahrokh Esfahani, Mohammad, Garofalo, Andrea, Li, Michael Yu, Rossi, Cédric, Flerlage, Tim, Flerlage, Jamie E., Adams, Ragini, Binkley, Michael S., Shukla, Navika, Jin, Michael C., Olsen, Mari, Telenius, Adèle, Mutter, Jurik A., Schroers-Martin, Joseph G., Sworder, Brian J., Rai, Shinya, King, Daniel A., Schultz, Andre, Bögeholz, Jan, Su, Shengqin, Kathuria, Karan R., Liu, Chih Long, Kang, Xiaoman, Strohband, Maya J., Langfitt, Deanna, Pobre-Piza, Kristine Faye, Surman, Sherri, Tian, Feng, Spina, Valeria, Tousseyn, Thomas, Buedts, Lieselot, Hoppe, Richard, Natkunam, Yasodha, Fornecker, Luc-Matthieu, Castellino, Sharon M., Advani, Ranjana, Rossi, Davide, Lynch, Ryan, Ghesquières, Hervé, Casasnovas, Olivier, Kurtz, David M., Marks, Lianna J., Link, Michael P., André, Marc, Vandenberghe, Peter, Steidl, Christian, Diehn, Maximilian, Alizadeh, Ash A.

“…The scarcity of malignant Hodgkin and Reed–Sternberg cells hampers tissue-based comprehensive genomic profiling of classic Hodgkin lymphoma (cHL). By contrast,…”
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Inferred Gene Expression By Cell-Free DNA Profiling Allows Noninvasive Lymphoma Classification by Mutter, Jurik A, Shahrokh Esfahani, Mohammad, Schroers-Martin, Joseph, Alig, Stefan K., Hamilton, Mark P., Sworder, Brian J., Tessoulin, Benoit, Boegeholz, Jan, Flerlage, Timothy, Flerlage, Jamie E., Binkley, Michael S., Sugio, Takeshi, Rossi, Cédric, Olsen, Mari, Liu, Chih Long, Le Gouill, Steven, Kurtz, David M., Diehn, Maximilian, Alizadeh, Ash A.

“…Background : Current diagnostic criteria for mature B-cell tumors require a combination of histopathological, immunophenotypic, cytogenetic, and genetic…”
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Genomic, Transcriptional, and Immunological Validation of Distinct Molecular Subtypes of Classic Hodgkin Lymphoma through Tissue-Based and Noninvasive Methods by Alig, Stefan K., Shahrokh Esfahani, Mohammad, Garofalo, Andrea, Li, Michael Yu, Rossi, Cédric, Flerlage, Timothy, Flerlage, Jamie E., Adams, Ragini, Binkley, Michael S., Shukla, Navika, Jin, Michael, Olsen, Mari, Telenius, Adele, Mutter, Jurik A, Schroers-Martin, Joseph, Sworder, Brian J., Rai, Shinya, King, Daniel, Schultz, Andre, Bögeholz, Jan Lukas, Su, Shengqin, Kathuria, Karan R, Liu, Chih Long, Kang, Xiaoman, Langfitt, Deanna M., Pobre-Piza, Kristine Faye, Tian, Feng, Strohband, Maya J., Spina, Valeria, Tousseyn, Thomas, Buedts, Lieselot, Fornecker, Luc-Matthieu, Castellino, Sharon M., Advani, Ranjana H., Rossi, Davide, Lynch, Ryan C, Ghesquieres, Herve, Casasnovas, Olivier, Kurtz, David M., Marks, Lianna J., Link, Michael P., Andre, Marc, Vandenberghe, Peter, Steidl, Christian, Diehn, Maximilian, Alizadeh, Ash A.

“…Introduction: The scarcity of malignant Hodgkin and Reed-Sternberg (HRS) cells has hampered comprehensive genomic profiling of classic Hodgkin lymphoma (cHL)…”
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