Search Results - "Swisher, Stephen G"

Pathological response after neoadjuvant chemotherapy in resectable non-small-cell lung cancers: proposal for the use of major pathological response as a surrogate endpoint by Hellmann, Matthew D, MD, Chaft, Jamie E, MD, William, William N, MD, Rusch, Valerie, Prof, Pisters, Katherine M W, Prof, Kalhor, Neda, MD, Pataer, Apar, MD, Travis, William D, Prof, Swisher, Stephen G, Prof, Kris, Mark G, Dr Prof

“…Summary Improvements in outcomes for patients with resectable lung cancers have plateaued. Clinical trials of resectable non-small-cell lung cancers with…”
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Landscape of EGFR-Dependent and -Independent Resistance Mechanisms to Osimertinib and Continuation Therapy Beyond Progression in EGFR -Mutant NSCLC by Le, Xiuning, Puri, Sonam, Negrao, Marcelo V, Nilsson, Monique B, Robichaux, Jacqulyne, Boyle, Theresa, Hicks, J Kevin, Lovinger, Katherine L, Roarty, Emily, Rinsurongkawong, Waree, Tang, Ming, Sun, Huiying, Elamin, Yasir, Lacerda, Lara C, Lewis, Jeff, Roth, Jack A, Swisher, Stephen G, Lee, J Jack, William, Jr, William N, Glisson, Bonnie S, Zhang, Jianjun, Papadimitrakopoulou, Vassiliki A, Gray, Jhanelle E, Heymach, John V

“…Osimertinib was initially approved for T790M-positive non-small cell lung cancer (NSCLC) and, more recently, for first-line treatment of -mutant NSCLC…”
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IASLC Multidisciplinary Recommendations for Pathologic Assessment of Lung Cancer Resection Specimens After Neoadjuvant Therapy by Travis, William D, Dacic, Sanja, Wistuba, Ignacio, Sholl, Lynette, Adusumilli, Prasad, Bubendorf, Lukas, Bunn, Paul, Cascone, Tina, Chaft, Jamie, Chen, Gang, Chou, Teh-Ying, Cooper, Wendy, Erasmus, Jeremy J, Ferreira, Carlos Gil, Goo, Jin-Mo, Heymach, John, Hirsch, Fred R, Horinouchi, Hidehito, Kerr, Keith, Kris, Mark, Jain, Deepali, Kim, Young T, Lopez-Rios, Fernando, Lu, Shun, Mitsudomi, Tetsuya, Moreira, Andre, Motoi, Noriko, Nicholson, Andrew G, Oliveira, Ricardo, Papotti, Mauro, Pastorino, Ugo, Paz-Ares, Luis, Pelosi, Giuseppe, Poleri, Claudia, Provencio, Mariano, Roden, Anja C, Scagliotti, Giorgio, Swisher, Stephen G, Thunnissen, Erik, Tsao, Ming S, Vansteenkiste, Johan, Weder, Walter, Yatabe, Yasushi

“…Currently, there is no established guidance on how to process and evaluate resected lung cancer specimens after neoadjuvant therapy in the setting of clinical…”
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Local consolidative therapy versus maintenance therapy or observation for patients with oligometastatic non-small-cell lung cancer without progression after first-line systemic therapy: a multicentre, randomised, controlled, phase 2 study by Gomez, Daniel R, Dr, Blumenschein, George R, Prof, Lee, J Jack, Prof, Hernandez, Mike, MS, Ye, Rong, MS, Camidge, D Ross, Prof, Doebele, Robert C, MD, Skoulidis, Ferdinandos, MD, Gaspar, Laurie E, Prof, Gibbons, Don L, MD, Karam, Jose A, MD, Kavanagh, Brian D, Prof, Tang, Chad, MD, Komaki, Ritsuko, Prof, Louie, Alexander V, MD, Palma, David A, MD, Tsao, Anne S, MD, Sepesi, Boris, MD, William, William N, MD, Zhang, Jianjun, MD, Shi, Qiuling, PhD, Wang, Xin Shelley, MD, Swisher, Stephen G, Prof, Heymach, John V, Prof

“…Summary Background Evidence from retrospective studies suggests that disease progression after first-line chemotherapy for metastatic non-small-cell lung…”
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Bayesian Adaptive Randomization Trial of Passive Scattering Proton Therapy and Intensity-Modulated Photon Radiotherapy for Locally Advanced Non-Small-Cell Lung Cancer by Liao, Zhongxing, Lee, J Jack, Komaki, Ritsuko, Gomez, Daniel R, O'Reilly, Michael S, Fossella, Frank V, Blumenschein, Jr, George R, Heymach, John V, Vaporciyan, Ara A, Swisher, Stephen G, Allen, Pamela K, Choi, Noah Chan, DeLaney, Thomas F, Hahn, Stephen M, Cox, James D, Lu, Charles S, Mohan, Radhe

“…Purpose This randomized trial compared outcomes of passive scattering proton therapy (PSPT) versus intensity-modulated (photon) radiotherapy (IMRT), both with…”
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Lobectomy, sublobar resection, and stereotactic ablative radiotherapy for early-stage non-small cell lung cancers in the elderly by Shirvani, Shervin M, Jiang, Jing, Chang, Joe Y, Welsh, James, Likhacheva, Anna, Buchholz, Thomas A, Swisher, Stephen G, Smith, Benjamin D

“…The incidence of early-stage non-small cell lung cancer (NSCLC) among the elderly is expected to rise dramatically owing to demographic trends and increased…”
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Randomized Phase IIB Trial of Proton Beam Therapy Versus Intensity-Modulated Radiation Therapy for Locally Advanced Esophageal Cancer by Lin, Steven H, Hobbs, Brian P, Verma, Vivek, Tidwell, Rebecca S, Smith, Grace L, Lei, Xiudong, Corsini, Erin M, Mok, Isabel, Wei, Xiong, Yao, Luyang, Wang, Xin, Komaki, Ritsuko U, Chang, Joe Y, Chun, Stephen G, Jeter, Melenda D, Swisher, Stephen G, Ajani, Jaffer A, Blum-Murphy, Mariela, Vaporciyan, Ara A, Mehran, Reza J, Koong, Albert C, Gandhi, Saumil J, Hofstetter, Wayne L, Hong, Theodore S, Delaney, Thomas F, Liao, Zhongxing, Mohan, Radhe

“…Whether dosimetric advantages of proton beam therapy (PBT) translate to improved clinical outcomes compared with intensity-modulated radiation therapy (IMRT)…”
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Image Analysis-based Assessment of PD-L1 and Tumor-Associated Immune Cells Density Supports Distinct Intratumoral Microenvironment Groups in Non-small Cell Lung Carcinoma Patients by Parra, Edwin R, Behrens, Carmen, Rodriguez-Canales, Jaime, Lin, Heather, Mino, Barbara, Blando, Jorge, Zhang, Jianjun, Gibbons, Don L, Heymach, John V, Sepesi, Boris, Swisher, Stephen G, Weissferdt, Annikka, Kalhor, Neda, Izzo, Julie, Kadara, Humam, Moran, Cesar, Lee, Jack J, Wistuba, Ignacio I

“…We investigated the correlation between immunohistochemical PD-L1 expression and tumor-associated immune cells (TAICs) density in non-small cell lung carcinoma…”
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Diagnostic accuracy of EUS in differentiating mucosal versus submucosal invasion of superficial esophageal cancers: a systematic review and meta-analysis by Thosani, Nirav, MD, MHA, Singh, Harvinder, MD, Kapadia, Asha, PhD, Ochi, Nobuo, MD, PhD, Lee, Jeffrey H., MD, Ajani, Jaffer, MD, Swisher, Stephen G., MD, Hofstetter, Wayne L., MD, Guha, Sushovan, MD, PhD, Bhutani, Manoop S., MD

“…Background The prognosis of esophageal cancer (EC) depends on the depth of tumor invasion and lymph node metastasis. EC limited to the mucosa (T1a) can be…”
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Stereotactic Ablative Radiation Therapy for Centrally Located Early Stage or Isolated Parenchymal Recurrences of Non-Small Cell Lung Cancer: How to Fly in a “No Fly Zone” by Chang, Joe Y., MD, PhD, Li, Qiao-Qiao, MD, Xu, Qing-Yong, MD, Allen, Pamela K., PhD, Rebueno, Neal, CMS, Gomez, Daniel R., MD, Balter, Peter, PhD, Komaki, Ritsuko, MD, Mehran, Reza, MD, Swisher, Stephen G., MD, Roth, Jack A., MD

“…Purpose We extended our previous experience with stereotactic ablative radiation therapy (SABR; 50 Gy in 4 fractions) for centrally located non-small cell lung…”
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Relationship between tumor size and survival in non-small-cell lung cancer (NSCLC): an analysis of the surveillance, epidemiology, and end results (SEER) registry by Zhang, Jianjun, Gold, Kathryn A, Lin, Heather Y, Swisher, Stephen G, Xing, Yan, Lee, J Jack, Kim, Edward S, William, Jr, William N

“…Tumor size is a known prognostic factor for early stage non-small-cell lung cancer (NSCLC), but its significance in node-positive and locally invasive NSCLC…”
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Oncogene-specific differences in tumor mutational burden, PD-L1 expression, and outcomes from immunotherapy in non-small cell lung cancer by Negrao, Marcelo V, Skoulidis, Ferdinandos, Montesion, Meagan, Schulze, Katja, Bara, Ilze, Shen, Vincent, Xu, Hao, Hu, Sylvia, Sui, Dawen, Elamin, Yasir Y, Le, Xiuning, Goldberg, Michael E, Murugesan, Karthikeyan, Wu, Chang-Jiun, Zhang, Jianhua, Barreto, David S, Robichaux, Jacqulyne P, Reuben, Alexandre, Cascone, Tina, Gay, Carl M, Mitchell, Kyle G, Hong, Lingzhi, Rinsurongkawong, Waree, Roth, Jack A, Swisher, Stephen G, Lee, Jack, Tsao, Anne, Papadimitrakopoulou, Vassiliki, Gibbons, Don L, Glisson, Bonnie S, Singal, Gaurav, Miller, Vincent A, Alexander, Brian, Frampton, Garrett, Albacker, Lee A, Shames, David, Zhang, Jianjun, Heymach, John V

“…BackgroundNon-small cell lung cancer (NSCLC) patients bearing targetable oncogene alterations typically derive limited benefit from immune checkpoint blockade…”
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Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma by Hu, Xin, Fujimoto, Junya, Ying, Lisha, Fukuoka, Junya, Ashizawa, Kazuto, Sun, Wenyong, Reuben, Alexandre, Chow, Chi-Wan, McGranahan, Nicholas, Chen, Runzhe, Hu, Jinlin, Godoy, Myrna C., Tabata, Kazuhiro, Kuroda, Kishio, Shi, Lei, Li, Jun, Behrens, Carmen, Parra, Edwin Roger, Little, Latasha D., Gumbs, Curtis, Mao, Xizeng, Song, Xingzhi, Tippen, Samantha, Thornton, Rebecca L., Kadara, Humam, Scheet, Paul, Roarty, Emily, Ostrin, Edwin Justin, Wang, Xu, Carter, Brett W., Antonoff, Mara B., Zhang, Jianhua, Vaporciyan, Ara A., Pass, Harvey, Swisher, Stephen G., Heymach, John V., Lee, J. Jack, Wistuba, Ignacio I., Hong, Waun Ki, Futreal, P. Andrew, Su, Dan, Zhang, Jianjun

“…There has been a dramatic increase in the detection of lung nodules, many of which are preneoplasia atypical adenomatous hyperplasia (AAH), adenocarcinoma in…”
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Propensity Score-based Comparison of Long-term Outcomes With 3-Dimensional Conformal Radiotherapy vs Intensity-Modulated Radiotherapy for Esophageal Cancer by Lin, Steven H., MD, PhD, Wang, Lu, PhD, Myles, Bevan, MD, Thall, Peter F., PhD, Hofstetter, Wayne L., MD, Swisher, Stephen G., MD, Ajani, Jaffer A., MD, Cox, James D., MD, Komaki, Ritsuko, MD, Liao, Zhongxing, MD

“…Purpose Although 3-dimensional conformal radiotherapy (3D-CRT) is the worldwide standard for the treatment of esophageal cancer, intensity modulated…”
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Robotic-Assisted Lobectomy for Non-Small Cell Lung Cancer: A Comprehensive Institutional Experience by Nelson, David B., Mehran, Reza J., Mitchell, Kyle G., Rajaram, Ravi, Correa, Arlene M., Bassett, Roland L., Antonoff, Mara B., Hofstetter, Wayne L., Roth, Jack A., Sepesi, Boris, Swisher, Stephen G., Walsh, Garrett L., Vaporciyan, Ara A., Rice, David C.

“…It is unclear whether the enhanced dexterity and visualization of the surgical robot lessens morbidity and influences staging or survival. We compared outcomes…”
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Long-Term Survival Outcomes of Cancer-Directed Surgery for Malignant Pleural Mesothelioma: Propensity Score Matching Analysis by Nelson, David B, Rice, David C, Niu, Jiangong, Atay, Scott, Vaporciyan, Ara A, Antonoff, Mara, Hofstetter, Wayne L, Walsh, Garrett L, Swisher, Stephen G, Roth, Jack A, Tsao, Anne, Gomez, Daniel, Giordano, Sharon H, Mehran, Reza, Sepesi, Boris

“…Purpose Small observational studies have shown a survival advantage to undergoing cancer-directed surgery for malignant pleural mesothelioma (MPM); however, it…”
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Nodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer by Cascone, Tina, Weissferdt, Annikka, Godoy, Myrna C. B., William, William N., Leung, Cheuk H., Lin, Heather Y., Basu, Sreyashi, Yadav, Shalini S., Pataer, Apar, Mitchell, Kyle G., Khan, Md Abdul Wadud, Shi, Yushu, Haymaker, Cara, Solis, Luisa M., Parra, Edwin R., Kadara, Humam, Wistuba, Ignacio I., Sharma, Padmanee, Allison, James P., Ajami, Nadim J., Wargo, Jennifer A., Jenq, Robert R., Gibbons, Don L., Lee, J. Jack, Swisher, Stephen G., Vaporciyan, Ara A., Heymach, John V., Sepesi, Boris

“…Radiographic imaging is the standard approach for evaluating the disease involvement of lymph nodes in patients with operable NSCLC although the impact of…”
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Is the Centralization of Complex Surgical Procedures an Unintended Spillover Effect of Global Capitation? – Insights from the Maryland Global Budget Revenue Program by Offodile, Anaeze C., Lin, Yu-Li, Shah, Shivani A., Swisher, Stephen G., Jain, Amit, Butler, Charles E., Aliu, Oluseyi

“…To determine if global budget revenue (GBR) models incent the centralization of complex surgical care. In 2014, Maryland initiated a statewide GBR model. While…”
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Predictors of Postoperative Complications After Trimodality Therapy for Esophageal Cancer by Wang, Jingya, MD, Wei, Caimiao, PhD, Tucker, Susan L., PhD, Myles, Bevan, MD, Palmer, Matthew, CMD, MBA, Hofstetter, Wayne L., MD, Swisher, Stephen G., MD, Ajani, Jaffer A., MD, Cox, James D., MD, Komaki, Ritsuko, MD, Liao, Zhongxing, MD, Lin, Steven H., MD, PhD

“…Purpose While trimodality therapy for esophageal cancer has improved patient outcomes, surgical complication rates remain high. The goal of this study was to…”
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Time to treatment as a quality metric in lung cancer: Staging studies, time to treatment, and patient survival by Gomez, Daniel R, Liao, Kai-Ping, Swisher, Stephen G, Blumenschein, George R, Erasmus, Jeremy J, Buchholz, Thomas A, Giordano, Sharon H, Smith, Benjamin D

“…Abstract Purpose Prompt staging and treatment are crucial for non-small cell lung cancer (NSCLC). We determined if predictors of treatment delay after…”
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