Search Results - "Swift, Pauline A"
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Safety and Efficacy of NVX-CoV2373 Covid-19 Vaccine
Published in The New England journal of medicine (23-09-2021)“…In a phase 3 trial involving more than 15,000 participants, two doses of NVX-CoV2373, a recombinant SARS-CoV-2 nanoparticle vaccine, administered 21 days apart…”
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Delivering clinical studies of exercise in the COVID-19 pandemic: challenges and adaptations using a feasibility trial of isometric exercise to treat hypertension as an exemplar
Published in BMJ open (17-03-2023)“…The COVID-19 pandemic has significantly impacted on the delivery of clinical trials in the UK, posing complicated organisational challenges and requiring…”
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The health impacts of dietary sodium and a low-salt diet
Published in Clinical medicine (London, England) (01-12-2015)“…High salt intake is now endemic worldwide. It contributes to the generation and maintenance of high blood pressure, which is now the biggest risk factor for…”
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An ontological approach to identifying cases of chronic kidney disease from routine primary care data: a cross-sectional study
Published in BMC nephrology (10-04-2018)“…Accurately identifying cases of chronic kidney disease (CKD) from primary care data facilitates the management of patients, and is vital for surveillance and…”
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The effect of intravenous iron supplementation on exercise capacity in iron-deficient but not anaemic patients with chronic kidney disease: study design and baseline data for a multicentre prospective double-blind randomised controlled trial
Published in BMC nephrology (27-07-2022)“…Many people living with chronic kidney disease (CKD) are iron deficient, even though they may not be anaemic. The Iron and Muscle study aims to evaluate…”
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Step-Wise Management of Anemia in Patients With Chronic Kidney Disease in Primary Care: Qualitative Study
Published in Journal of primary care & community health (01-01-2023)“…Introduction: Anemia is common in chronic kidney disease (CKD) and is associated with increased cardiovascular risk and reduced quality of life, but is often…”
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Nocturnal blood pressure and progression to end-stage renal disease or death in nondiabetic chronic kidney disease stages 3 and 4
Published in Journal of hypertension (01-03-2010)“…OBJECTIVEThe objective was to assess the role of office and ambulatory blood pressure (BP) on the development of end-stage renal disease (ESRD) in nondiabetic…”
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Sodium‐glucose cotransporter‐2 inhibitors and kidney outcomes in real‐world type 2 diabetes populations: A systematic review and meta‐analysis of observational studies
Published in Diabetes, obesity & metabolism (01-08-2023)“…Aim To conduct a systematic review of observational studies to explore the real‐world kidney benefits of sodium‐glucose cotransporter‐2 (SGLT2) inhibitors in a…”
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Safety and Efficacy of the NVX-CoV2373 Coronavirus Disease 2019 Vaccine at Completion of the Placebo-Controlled Phase of a Randomized Controlled Trial
Published in Clinical infectious diseases (08-02-2023)“…The recombinant protein-based vaccine, NVX-CoV2373, demonstrated 89.7% efficacy against coronavirus disease 2019 (COVID-19) in a phase 3, randomized,…”
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A Comparison of Sodium-Glucose Co-Transporter 2 Inhibitor Kidney Outcome Trial Participants with a Real-World Chronic Kidney Disease Primary Care Population
Published in Nephrology, dialysis, transplantation (22-03-2024)“…Observational studies suggest sodium-glucose co-transporter-2 (SGLT2) inhibitor kidney outcome trials are not representative of the broader population of…”
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The Relationship between Serum Sodium Concentration and Albuminuria: A Retrospective Cohort Study
Published in Nephron (2015) (2024)“…Lowering dietary salt intake reduces albuminuria, an early marker of renal damage and a sensitive predictor of adverse cardiovascular outcomes. The mechanisms…”
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Uncertainties in BP management in dialysis patients
Published in Seminars in dialysis (01-05-2020)“…Hypertension in dialysis patients is extremely common. In this article, we review the current evidence for blood pressure (BP) goals in hemodialysis patients,…”
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The effect of dietary salt on blood pressure in individuals receiving chronic dialysis: a systematic review and meta-analysis of randomised controlled trials
Published in Journal of human hypertension (01-04-2019)“…Dietary salt reduction in the general population lowers blood pressure and cardiovascular risk. Despite being widely recommended, there is limited evidence as…”
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The predictive role of symptoms in COVID-19 diagnostic models: A longitudinal insight
Published in Epidemiology and infection (22-01-2024)“…To investigate the symptoms of SARS-CoV-2 infection, their dynamics and their discriminatory power for the disease using longitudinally, prospectively…”
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Serum sodium concentration and the progression of established chronic kidney disease
Published in Journal of nephrology (01-04-2019)“…Background Higher serum sodium concentration has been reported to be a risk factor for the development of incident chronic kidney disease (CKD), but its…”
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Acute Renal Failure in Association with Community-Acquired Clostridium difficile Infection and McKittrick-Wheelock Syndrome
Published in Case reports in gastroenterology (18-08-2011)“…We report the case of a 65-year-old Caucasian woman who experienced two separate episodes of acute renal failure within an 18-month period, both requiring…”
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The association between serum sodium concentration, hypertension and primary cardiovascular events: a retrospective cohort study
Published in Journal of human hypertension (01-01-2019)“…The mechanisms underlying the adverse cardiovascular effects of increased salt intake are incompletely understood, but parallel increases in serum sodium…”
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An Alternative Approach to Delivering Intensive Dialysis in Pregnancy
Published in Peritoneal dialysis international (01-09-2016)“…Pregnancy outcomes in patients with end-stage renal disease (ESRD) on dialysis are improving. Recent literature supports intensive hemodialysis (HD) as the…”
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Implementation of chronic kidney disease guidelines for sodium-glucose co-transporter-2 inhibitor use in primary care in the UK: a cross-sectional study
Published in EClinicalMedicine (01-02-2024)“…The cardiovascular and kidney benefits of sodium-glucose co-transporter-2 (SGLT2) inhibitors in people with chronic kidney disease (CKD) are well established…”
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