Search Results - "Swift, Luther M"
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Demographic and Methodological Heterogeneity in Electrocardiogram Signals From Guinea Pigs
Published in Frontiers in physiology (02-06-2022)“…Electrocardiograms (ECG) are universally used to measure the electrical activity of the heart; however, variations in recording techniques and/or subject…”
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2
Bisphenol A exposure and cardiac electrical conduction in excised rat hearts
Published in Environmental health perspectives (01-04-2014)“…Bisphenol A (BPA) is used to produce polycarbonate plastics and epoxy resins that are widely used in everyday products, such as food and beverage containers,…”
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3
KairoSight: Open-Source Software for the Analysis of Cardiac Optical Data Collected From Multiple Species
Published in Frontiers in physiology (29-10-2021)“…Cardiac optical mapping, also known as optocardiography, employs parameter-sensitive fluorescence dye(s) to image cardiac tissue and resolve the electrical and…”
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Properties of blebbistatin for cardiac optical mapping and other imaging applications
Published in Pflügers Archiv (01-11-2012)“…Blebbistatin is a recently discovered myosin II inhibitor. It is rapidly becoming a compound of choice to reduce motion artifacts during cardiac optical…”
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5
Seeing the Invisible: Revealing Atrial Ablation Lesions Using Hyperspectral Imaging Approach
Published in PloS one (08-12-2016)“…Currently, there are limited means for high-resolution monitoring of tissue injury during radiofrequency ablation procedures. To develop the next generation of…”
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KairoSight-3.0: A validated optical mapping software to characterize cardiac electrophysiology, excitation-contraction coupling, and alternans
Published in Journal of Molecular and Cellular Cardiology Plus (Online) (01-09-2023)“…Cardiac optical mapping is an imaging technique that measures fluorescent signals across a cardiac preparation. Dual optical imaging of voltage-sensitive and…”
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Bisphenol S and Bisphenol F Are Less Disruptive to Cardiac Electrophysiology, as Compared With Bisphenol A
Published in Toxicological sciences (01-09-2021)“…Abstract Bisphenol A (BPA) is a high-production volume chemical used to manufacture consumer and medical-grade plastic products. Due to its ubiquity, the…”
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8
Stop the beat to see the rhythm: excitation-contraction uncoupling in cardiac research
Published in American journal of physiology. Heart and circulatory physiology (01-12-2021)“…Optical mapping is an imaging technique that is extensively used in cardiovascular research, wherein parameter-sensitive fluorescent indicators are used to…”
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Age-dependent changes in electrophysiology and calcium handling: implications for pediatric cardiac research
Published in American journal of physiology. Heart and circulatory physiology (01-02-2020)“…Rodent models are frequently employed in cardiovascular research, yet our understanding of pediatric cardiac physiology has largely been deduced from more…”
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10
Evidence for the cardiodepressive effects of the plasticizer di-2-ethylhexyl phthalate
Published in Toxicological sciences (01-01-2024)“…Abstract Di-2-ethylhexyl phthalate (DEHP) is commonly used in the manufacturing of plastic materials, including intravenous bags, blood storage bags, and…”
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11
Electroanatomical adaptations in the guinea pig heart from neonatal to adulthood
Published in Europace (London, England) (02-07-2024)“…Abstract Aims Electroanatomical adaptations during the neonatal to adult phase have not been comprehensively studied in preclinical animal models. To explore…”
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12
Localization of dichlorofluorescin in cardiac myocytes: implications for assessment of oxidative stress
Published in American journal of physiology. Heart and circulatory physiology (01-03-2000)“…Localization and staining features of the oxidant-sensitive fluorescent probe 2'7'-dichlorofluorescin (DCFH) were evaluated in isolated cardiac muscle cells…”
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13
NADH fluorescence imaging of isolated biventricular working rabbit hearts
Published in Journal of visualized experiments (24-07-2012)“…Since its inception by Langendorff(1), the isolated perfused heart remains a prominent tool for studying cardiac physiology(2). However, it is not well-suited…”
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14
Phthalate Exposure Changes the Metabolic Profile of Cardiac Muscle Cells
Published in Environmental health perspectives (01-09-2012)“…Background: Phthalates are common plasticizers present in medical-grade plastics and other everyday products. They can also act as endocrine-disrupting…”
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15
Hyperspectral imaging for label-free in vivo identification of myocardial scars and sites of radiofrequency ablation lesions
Published in Heart rhythm (01-04-2018)“…Treatment of cardiac arrhythmias often involves ablating viable muscle tissue within or near islands of scarred myocardium. Yet, today there are limited means…”
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16
Autofluorescence hyperspectral imaging of radiofrequency ablation lesions in porcine cardiac tissue
Published in Journal of biophotonics (01-08-2017)“…Radiofrequency ablation (RFA) is a widely used treatment for atrial fibrillation, the most common cardiac arrhythmia. Here, we explore autofluorescence…”
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17
Functional response of the isolated, perfused normoxic heart to pyruvate dehydrogenase activation by dichloroacetate and pyruvate
Published in Pflügers Archiv (01-01-2016)“…Dichloroacetate (DCA) and pyruvate activate pyruvate dehydrogenase (PDH), a key enzyme that modulates glucose oxidation and mitochondrial NADH production. Both…”
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18
Changes in phospholipid content and myocardial calcium-independent phospholipase A2 activity during chronic anthracycline administration
Published in The Journal of pharmacology and experimental therapeutics (01-11-2004)“…Despite numerous investigations, the causes underlying anthracycline cardiomyopathy are yet to be established. We have recently reported that acute treatment…”
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Localized injury in cardiomyocyte network: a new experimental model of ischemia-reperfusion arrhythmias
Published in American journal of physiology. Heart and circulatory physiology (01-04-2001)“…We developed a new experimental approach to study the effects of local injury in a multicellular preparation and tested the ability of the method to induce…”
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Clinically relevant concentrations of di (2-ethylhexyl) phthalate (DEHP) uncouple cardiac syncytium
Published in Toxicology and applied pharmacology (01-04-2009)“…Di(2-ethylhexyl) phthalate (DEHP) is a widely used plasticizer found in a variety of polyvinyl chloride (PVC) medical products. The results of studies in…”
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