Search Results - "Swift, Jody L."

Live-cell microscopy - tips and tools by Frigault, Melanie M, Lacoste, Judith, Swift, Jody L, Brown, Claire M

“…Imaging of living cells and tissue is now common in many fields of the life and physical sciences, and is instrumental in revealing a great deal about cellular…”
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Revealing protein oligomerization and densities in situ using spatial intensity distribution analysis by Godin, Antoine G., Costantino, Santiago, Lorenzo, Louis-Etienne, Swift, Jody L., Sergeev, Mikhail, Ribeiro-da-Silva, Alfredo, De Koninck, Yves, Wiseman, Paul W., Snyder, Solomon H.

“…Measuring protein interactions is key to understanding cell signaling mechanisms, but quantitative analysis of these interactions in situ has remained a major…”
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Quantification of receptor tyrosine kinase transactivation through direct dimerization and surface density measurements in single cells by Swift, Jody L, Godin, Antoine G, Doré, Kim, Freland, Laure, Bouchard, Nathalie, Nimmo, Chelsea, Sergeev, Mikhail, De Koninck, Yves, Wiseman, Paul W, Beaulieu, Jean-Martin

“…Cell signaling involves dynamic changes in protein oligomerization leading to the formation of different signaling complexes and modulation of activity…”
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Nanoparticles as Fluorescence Labels: Is Size All that Matters? by Swift, Jody L., Cramb, David T.

“…Fluorescent labels are often used in bioassays as a means to detect and characterize ligand-receptor binding. This is due in part to the inherently high…”
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Fluorescence correlation spectroscopy using quantum dots: advances, challenges and opportunities by Heuff, Romey F, Swift, Jody L, Cramb, David T

“…Semiconductor nanocrystals (quantum dots) have been increasingly employed in measuring the dynamic behavior of biomacromolecules using fluorescence correlation…”
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Ligand-induced clustering of EGF receptors: A quantitative study by fluorescence image moment analysis by Sergeev, Mikhail, Swift, Jody L., Godin, Antoine G., Wiseman, Paul W.

“…Fluorescence microscopy is widely used in the life sciences, but largely for qualitative imaging. Here we apply a bioanalytical technique, fluorescence image…”
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Spatial intensity distribution analysis (SpIDA): a new tool for receptor tyrosine kinase activation and transactivation quantification by Barbeau, Annie, Swift, Jody L, Godin, Antoine G, De Koninck, Yves, Wiseman, Paul W, Beaulieu, Jean-Martin

“…This chapter presents a general approach for the application of spatial intensity distribution analysis (SpIDA) to pharmacodynamic quantification of receptor…”
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Effects of Various Small-Molecule Anesthetics on Vesicle Fusion: A Study Using Two-Photon Fluorescence Cross-Correlation Spectroscopy by Nguyen, Trinh T, Swift, Jody L, Burger, Melanie C, Cramb, David T

“…Currently, the molecular mechanism for membrane fusion remains unconfirmed. The most compelling suggested mechanism is the stalk hypothesis, which states that…”
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Two-Photon Excitation Fluorescence Cross-Correlation Assay for Ligand−Receptor Binding:  Cell Membrane Nanopatches Containing the Human μ-Opioid Receptor by Swift, Jody L, Burger, Melanie C, Massotte, Dominique, Dahms, Tanya E. S, Cramb, David T

“…Current ligand−receptor binding assays for G-protein coupled receptors cannot directly measure the system's dissociation constant, K d, without purification of…”
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A quantum dot-labeled ligand-receptor binding assay for G protein-coupled receptors contained in minimally purified membrane nanopatches by Swift, Jody L, Burger, Melanie C, Cramb, David T

“…A robust method to directly measure ligand-receptor binding interactions using fluorescence cross-correlation spectroscopy (FCCS) is described. The example…”
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Fluorescence microscopy investigations of ligand propagation and accessibility under adherent cells by Swift, Jody L, Sergeev, Mikhail, Wiseman, Paul W

“…Fluorescence microscopy methods including total internal reflection fluorescence and confocal laser scanning microscopy have played a major role in modern cell…”
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Anesthetic-Enhanced Membrane Fusion Examined Using Two-Photon Fluorescence Correlation Spectroscopy by Swift, Jody L, Carnini, Anna, Dahms, Tanya E. S, Cramb, David T

“…Vesicle fusion has been used as a model for viral fusion with cells, but measuring the kinetics of the process simultaneously with vesicle size has been…”
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Quantification of receptor tyrosine kinase activation and transactivation by G-protein-coupled receptors using spatial intensity distribution analysis (SpIDA) by Barbeau, Annie, Godin, Antoine G, Swift, Jody L, De Koninck, Yves, Wiseman, Paul W, Beaulieu, Jean-Martin

“…This chapter presents a general approach for the application of spatial intensity distribution analysis (SpIDA) to the pharmacodynamic quantification of…”
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Effects of Oversampling and Scanning Artifacts on the Accuracy of Spatial Fluorescence Intensity Fluctuation Analysis Methods by Sergeev, Mikhail, Godin, Antoine G., Swift, Jody L., De Koninck, Yves, Wiseman, Paul W.

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Live Cell Imaging: Tips and Tools by Frigault, Melanie M., Lacoste, Judith, Swift, Jody L., Brown, Claire M.

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Receptor Transactivation Measured in Live Cells Using Spatial Intensity Distribution Analysis (spida) by Godin, Antoine G., Swift, Jody L., Doré, Kim, Sergeev, Mikhail, Freland, Laure, De Koninck, Yves, Beaulieu, Martin J., Wiseman, Paul W.

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Two-photon excitation fluorescence cross-correlation assay for ligand-receptor binding: cell membrane nanopatches containing the human micro-opioid receptor by Swift, Jody L, Burger, Melanie C, Massotte, Dominique, Dahms, Tanya E S, Cramb, David T

“…Current ligand-receptor binding assays for G-protein coupled receptors cannot directly measure the system's dissociation constant, Kd, without purification of…”
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Spatial Intensity Distribution Analysis (SpIDA) by Barbeau, Annie, Swift, Jody L., Godin, Antoine G., De Koninck, Yves, Wiseman, Paul W., Beaulieu, Jean-Martin

“…This chapter presents a general approach for the application of spatial intensity distribution analysis (SpIDA) to pharmacodynamic quantification of receptor…”
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