Search Results - "Swiderski, L."

Combinatorial Atoh1 and Gfi1 induction enhances hair cell regeneration in the adult cochlea by Lee, Sungsu, Song, Jae-Jun, Beyer, Lisa A., Swiderski, Donald L., Prieskorn, Diane M., Acar, Melih, Jen, Hsin-I, Groves, Andrew K., Raphael, Yehoash

“…Mature mammalian cochlear hair cells (HCs) do not spontaneously regenerate once lost, leading to life-long hearing deficits. Attempts to induce HC regeneration…”
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Scintillation Properties of LuAG:Ce, YAG:Ce and LYSO:Ce Crystals for Gamma-Ray Detection by Chewpraditkul, W., Swiderski, L., Moszynski, M., Szczesniak, T., Syntfeld-Kazuch, A., Wanarak, C., Limsuwan, P.

“…The scintillation properties of LuAG:Ce and YAG:Ce crystals were compared with LYSO:Ce crystal under ¿ -ray excitation. Light yield non-proportionality and…”
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Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals by Raphael, Yehoash, Izumikawa, Masahiko, Minoda, Ryosei, Kawamoto, Kohei, Abrashkin, Karen A, Swiderski, Donald L, Dolan, David F, Brough, Douglas E

“…In the mammalian auditory system, sensory cell loss resulting from aging, ototoxic drugs, infections, overstimulation and other causes is irreversible and…”
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Inappropriate p53 activation during development induces features of CHARGE syndrome by Van Nostrand, Jeanine L., Brady, Colleen A., Jung, Heiyoun, Fuentes, Daniel R., Kozak, Margaret M., Johnson, Thomas M., Lin, Chieh-Yu, Lin, Chien-Jung, Swiderski, Donald L., Vogel, Hannes, Bernstein, Jonathan A., Attié-Bitach, Tania, Chang, Ching-Pin, Wysocka, Joanna, Martin, Donna M., Attardi, Laura D.

“…Inappropriate activation of the tumour-suppressor protein p53 during development can promote phenotypes similar to those of CHARGE syndrome, suggesting that…”
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Scar Formation and Debris Elimination during Hair Cell Degeneration in the Adult DTR Mouse by Lee, Sungsu, Kurioka, Takaomi, Lee, Min Young, Beyer, Lisa A., Swiderski, Donald L., Ritter, K. Elaine, Raphael, Yehoash

“…•The cochlear sensory epithelium changes rapidly after DT insult in the DTR mouse.•Hair cell degeneration involves epithelial reorganization similar to…”
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Differential Effects of AAV.BDNF and AAV.Ntf3 in the Deafened Adult Guinea Pig Ear by Budenz, Cameron L., Wong, Hiu Tung, Swiderski, Donald L., Shibata, Seiji B., Pfingst, Bryan E., Raphael, Yehoash

“…Cochlear hair cell loss results in secondary regression of peripheral auditory fibers (PAFs) and loss of spiral ganglion neurons (SGNs). The performance of…”
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Cochlear Health and Cochlear-implant Function by Schvartz-Leyzac, Kara C., Colesa, Deborah J., Swiderski, Donald L., Raphael, Yehoash, Pfingst, Bryan E.

“…The cochlear implant (CI) is widely considered to be one of the most innovative and successful neuroprosthetic treatments developed to date. Although outcomes…”
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Advanced automatic detection of fetal body movements from multichannel magnetocardiographic signals by Schmidt, A, Witte, R, Swiderski, L, Zöllkau, J, Schneider, U, Hoyer, D

“…Both heart rate (HR) monitoring and detection and description of fetal movements provide essential information of the integrity of in utero development and…”
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CHD7 and retinoic acid signaling cooperate to regulate neural stem cell and inner ear development in mouse models of CHARGE syndrome by Micucci, Joseph A, Layman, Wanda S, Hurd, Elizabeth A, Sperry, Ethan D, Frank, Sophia F, Durham, Mark A, Swiderski, Donald L, Skidmore, Jennifer M, Scacheri, Peter C, Raphael, Yehoash, Martin, Donna M

“…CHARGE syndrome is a multiple congenital anomaly disorder that leads to life-threatening birth defects, such as choanal atresia and cardiac malformations as…”
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Survival of human embryonic stem cells implanted in the guinea pig auditory epithelium by Lee, Min Young, Hackelberg, Sandra, Green, Kari L., Lunghamer, Kelly G., Kurioka, Takaomi, Loomis, Benjamin R., Swiderski, Donald L., Duncan, R. Keith, Raphael, Yehoash

“…Hair cells in the mature cochlea cannot spontaneously regenerate. One potential approach for restoring hair cells is stem cell therapy. However, when cells are…”
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GJB2 gene therapy and conditional deletion reveal developmental stage-dependent effects on inner ear structure and function by Guo, Jingying, Ma, Xiaobo, Skidmore, Jennifer M., Cimerman, Jelka, Prieskorn, Diane M., Beyer, Lisa A., Swiderski, Donald L., Dolan, David F., Martin, Donna M., Raphael, Yehoash

“…Pathogenic variants in GJB2, the gene encoding connexin 26, are the most common cause of autosomal-recessive hereditary deafness. Despite this high prevalence,…”
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BDNF gene therapy induces auditory nerve survival and fiber sprouting in deaf Pou4f3 mutant mice by Fukui, H., Wong, H. T., Beyer, L. A., Case, B. G., Swiderski, D. L., Di Polo, A., Ryan, A. F., Raphael, Y.

“…Current therapy for patients with hereditary absence of cochlear hair cells, who have severe or profound deafness, is restricted to cochlear implantation, a…”
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The time-of-flight method for characterizing the neutron response of liquid organic scintillators by Iwanowska, J., Swiderski, L., Krakowski, T., Moszynski, M., Szczesniak, T., Pausch, G.

“…The purpose of this work is to present a measurement method for determining the neutron responses of various liquid organic scintillators using a…”
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Response of the flat cochlear epithelium to forced expression of Atoh1 by Izumikawa, Masahiko, Batts, Shelley A., Miyazawa, Toru, Swiderski, Donald L., Raphael, Yehoash

“…Following hair cell elimination in severely traumatized cochleae, differentiated supporting cells are often replaced by a simple epithelium with cuboidal or…”
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SWAN - Detection of explosives by means of fast neutron activation analysis by Gierlik, M., Borsuk, S., Guzik, Z., Iwanowska, J., Kaźmierczak, Ł., Korolczuk, S., Kozłowski, T., Krakowski, T., Marcinkowski, R., Swiderski, L., Szeptycka, M., Szewiński, J., Urban, A.

“…In this work we report on SWAN, the experimental, portable device for explosives detection. The device was created as part of the EU Structural Funds Project…”
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The High Efficiency fast-Response GAmma (HERGA) detector based on SiPM readout by Altomare, C., Cerasole, D., Di Venere, L., Fanchini, E., Gargano, F., Giordano, F., Loparco, F., Loporchio, S., Mastroserio, A., Morichi, M., Pantaleo, F.R., Serini, D., Spinelli, P., Swiderski, L.

“…Gamma-ray spectroscopy and gamma-ray imaging are two complementary techniques used for the localization and the identification of radioactive sources…”
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Energy Resolution of Scintillation Detectors-New Observations by Moszynski, M., Nassalski, A., Syntfeld-Kazuch, A., Swiderski, L., Szczesniak, T.

“…According to the present knowledge, the non-proportionality of the light yield of scintillators appears to be the fundamental limitation of energy resolution…”
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ACEMg Diet Supplement Modifies Progression of Hereditary Deafness by Green, Kari L., Swiderski, Donald L., Prieskorn, Diane M., DeRemer, Susan J., Beyer, Lisa A., Miller, Josef M., Green, Glenn E., Raphael, Yehoash

“…Dietary supplements consisting of beta-carotene (precursor to vitamin A), vitamins C and E and the mineral magnesium (ACEMg) can be beneficial for reducing…”
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Energy Resolution and Slow Components in Undoped CsI Crystals by Moszynski, M., Syntfeld-Kazuch, A., Swiderski, L., Sibczynski, P., Grodzicka, M., Szczesniak, T., Gektin, A. V., Schotanus, P., Shiran, N., Williams, R. T.

“…According to the present knowledge, the non-proportionality of the light yield of scintillators appears to be the fundamental limitation of energy resolution…”
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Light Yield Non-Proportionality and Energy Resolution of Praseodymium Doped LuAG Scintillator by Swiderski, L., Moszynski, M., Nassalski, A., Syntfeld-Kazuch, A., Szczesniak, T., Kamada, K., Tsutsumi, K., Usuki, Y., Yanagida, T., Yoshikawa, A.

“…Scintillation properties of praseodymium doped LuAG have been investigated. The crystal is a dense (6.7 g/cm 3 ) scintillator with a short decay time around 20…”
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