Search Results - "Swiderek, Kristine"

Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo by Moldt, Brian, Rakasz, Eva G, Schultz, Niccole, Chan-Hui, Po-Ying, Swiderek, Kristine, Weisgrau, Kimberly L, Piaskowski, Shari M, Bergman, Zachary, Watkins, David I, Poignard, Pascal, Burton, Dennis R

“…Most animal studies using passive administration of HIV broadly neutralizing monoclonal antibodies (bnMAbs) have associated protection against high-dose…”
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Efficacy and Safety of Treatment With an Anti-M2e Monoclonal Antibody in Experimental Human Influenza by Ramos, Eleanor L., Mitcham, Jennifer L., Koller, Teri D., Bonavia, Aurelio, Usner, Dale W., Balaratnam, Ganesh, Fredlund, Paul, Swiderek, Kristine M.

“…Background. The efficacy of TCN-032, a human monoclonal antibody targeting a conserved epitope on M2e, was explored in experimental human influenza. Methods…”
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The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity by Maurer, Mark F., Lewis, Katherine E., Kuijper, Joseph L., Ardourel, Dan, Gudgeon, Chelsea J., Chandrasekaran, Siddarth, Mudri, Sherri L., Kleist, Kayla N., Navas, Chris, Wolfson, Martin F., Rixon, Mark W., Swanson, Ryan, Dillon, Stacey R., Levin, Steven D., Kimbung, Yengo Raymond, Akutsu, Masato, Logan, Derek T., Walse, Björn, Swiderek, Kristine M., Peng, Stanford L.

“…Despite the recent clinical success of T cell checkpoint inhibition targeting the CTLA-4 and PD-1 pathways, many patients either fail to achieve objective…”
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A Tenascin-C Aptamer Identified by Tumor Cell SELEX: Systematic Evolution of Ligands by Exponential Enrichment by Daniels, Dion A., Chen, Hang, Hicke, Brian J., Swiderek, Kristine M., Gold, Larry

“…The targeting of molecular repertoires to complex systems rather than biochemically pure entities is an accessible approach that can identify proteins of…”
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The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies by Sok, Devin, Laserson, Uri, Laserson, Jonathan, Liu, Yi, Vigneault, Francois, Julien, Jean-Philippe, Briney, Bryan, Ramos, Alejandra, Saye, Karen F, Le, Khoa, Mahan, Alison, Wang, Shenshen, Kardar, Mehran, Yaari, Gur, Walker, Laura M, Simen, Birgitte B, St John, Elizabeth P, Chan-Hui, Po-Ying, Swiderek, Kristine, Kleinstein, Steven H, Kleinstein, Stephen H, Alter, Galit, Seaman, Michael S, Chakraborty, Arup K, Koller, Daphne, Wilson, Ian A, Church, George M, Burton, Dennis R, Poignard, Pascal

“…Broadly neutralizing HIV antibodies (bnAbs) are typically highly somatically mutated, raising doubts as to whether they can be elicited by vaccination. We used…”
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Preclinical characterization of MTX-101: a novel bispecific CD8 Treg modulator that restores CD8 Treg functions to suppress pathogenic T cells in autoimmune diseases by Gardell, Jennifer L., Maurer, Meghan E., Childs, Monica M., Pham, Minh N., Meengs, Brent, Julien, Susan H., Tan, Cong, Boster, Daniel R., Quach, Phoenicia, Therriault, Jon H., Hermansky, Gleda, Patton, Daniel T., Bowser, Justin, Chen, Alex, Morgan, Nadine N., Gilbertson, Emily A., Bogatzki, Lisa, Encarnacion, Kaelen, McMahan, Catherine J., Crane, Courtney A., Swiderek, Kristine M.

“…Introduction Regulatory CD8 T cells (CD8 Treg) are responsible for the selective killing of self-reactive and pathogenic CD4 T cells. In autoimmune disease,…”
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Partial efficacy of a broadly neutralizing antibody against cell-associated SHIV infection by Parsons, Matthew S, Lloyd, Sarah B, Lee, Wen Shi, Kristensen, Anne B, Amarasena, Thakshila, Center, Rob J, Keele, Brandon F, Lifson, Jeffrey D, LaBranche, Celia C, Montefiori, David, Wines, Bruce D, Hogarth, P Mark, Swiderek, Kristine M, Venturi, Vanessa, Davenport, Miles P, Kent, Stephen J

“…Broadly neutralizing antibodies (BnAbs) protect macaques from cell-free simian/human immunodeficiency virus (SHIV) challenge, but their efficacy against…”
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ICOSL + plasmacytoid dendritic cells as inducer of graft-versus-host disease, responsive to a dual ICOS/CD28 antagonist by Adom, Djamilatou, Dillon, Stacey R, Yang, Jinfeng, Liu, Hao, Ramadan, Abdulraouf, Kushekhar, Kushi, Hund, Samantha, Albright, Amanda, Kirksey, Maykala, Adeniyan, Titilayo, Lewis, Katherine E, Evans, Lawrence, Wu, Rebecca, Levin, Steven D, Mudri, Sherri, Yang, Jing, Rickel, Erika, Seaberg, Michelle, Henderson, Katherine, Gudgeon, Chelsea J, Wolfson, Martin F, Swanson, Ryan M, Swiderek, Kristine M, Peng, Stanford L, Hippen, Keli L, Blazar, Bruce R, Paczesny, Sophie

“…Acute graft-versus-host disease (aGVHD) remains a major complication of allogeneic hematopoietic cell transplantation (HCT). CD146 and CCR5 are proteins that…”
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Abstract 870: Derivation and characterization of antibodies from immune checkpoint blockade treated cancer patients by Branum, Mark, Smith, Laura, Brett, Heather, Algate, Paul, Greenfield, Brad, Brown, William, Swiderek, Kristine M.

“…Abstract The IgG+ memory B cell repertoire of cancer patients demonstrating durable responses to immune checkpoint blockade therapy has been interrogated to…”
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Immunological considerations for developing antibody therapeutics for Influenza A by Chan-Hui, Po-Ying, Swiderek, Kristine M

“…Influenza infection can give rise to serious illness leading to complications and hospitalization of patients. The efficacy of current standard of care is very…”
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Functional Interaction of Heterogeneous Nuclear Ribonucleoprotein C with Poliovirus RNA Synthesis Initiation Complexes by BRUNNER, Jo Ellen, NGUYEN, Joseph H. C, ROEHL, Holger H, HO, Tri V, SWIDEREK, Kristine M, SEMLER, Bert L

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cloning and Characterization of Inducible Nitric Oxide Synthase from Mouse Macrophages by Xie, Qiao-wen, Cho, Hearn J., Calaycay, Jimmy, Mumford, Richard A., Swiderek, Kristine M., Lee, Terry D., Ding, Aihao, Troso, Tiffany, Nathan, Carl

“…Nitric oxide (NO) conveys a variety of messages between cells, including signals for vasorelaxation, neurotransmission, and cytotoxicity. In some endothelial…”
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Correction: The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies by Sok, Devin, Laserson, Uri, Laserson, Jonathan, Liu, Yi, Vigneault, Francois, Julien, Jean-Philippe, Briney, Bryan, Ramos, Alejandra, Saye, Karen F., Le, Khoa, Mahan, Alison, Wang, Shenshen, Kardar, Mehran, Yaari, Gur, Walker, Laura M., Simen, Birgitte B., St. John, Elizabeth P., Chan-Hui, Po-Ying, Swiderek, Kristine, Kleinstein, Stephen H., Alter, Galit, Seaman, Michael S., Chakraborty, Arup K., Koller, Daphne, Wilson, Ian A., Church, George M., Burton, Dennis R., Poignard, Pascal

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P-type calcium channels blocked by the spider toxin omega-Aga-IVA by Mintz, I.M, Venema, V.J, Swiderek, K.M, Lee, T.D, Bean, B.P, Adams, M.E

“…Voltage dependent calcium channels mediate calcium entry into neurons, which is crucial for many processes in the brain including synaptic transmission,…”
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Physiological effects of unassembled chaperonin Cct subunits in the yeast Saccharomyces cerevisiae by Anaul Kabir, M., Kaminska, Joanna, Segel, George B., Bethlendy, Gabor, Lin, Paul, Della Seta, Flavio, Blegen, Casey, Swiderek, Kristine M., Żołądek, Teresa, Arndt, Kim T., Sherman, Fred

“…Eukaryotic chaperonins, the Cct complexes, are assembled into two rings, each of which is composed of a stoichiometric array of eight different subunits, which…”
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Definition of the full extent of glycosylation of the 45-kilodalton glycoprotein of Mycobacterium tuberculosis by Dobos, K M, Khoo, K H, Swiderek, K M, Brennan, P J, Belisle, J T

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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97-OR: Preclinical Characterization of MTX-101, a Novel KIRxCD8 Targeting Bispecific CD8 Treg Modulator by Patton, Daniel, Pham, Minh, Gardell, Jennifer L, Boster, Daniel, Julien, Susan, Mcmahan, Catherine, Crane, Courtney, Swiderek, Kristine M

“…Introduction and Objectives: In healthy individuals, activation and expansion of CD8 regulatory T cells (CD8 Treg) leads to selective killing of pathogenic CD4…”
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Cloning of the mspA gene encoding a porin from Mycobacterium smegmatis by Niederweis, Michael, Ehrt, Sabine, Heinz, Christian, Klöcker, Uta, Karosi, Stefanie, Swiderek, Kristine M., Riley, Lee W., Benz, Roland

“…Porins form channels in the mycolic acid layer of mycobacteria and thereby control access of hydrophilic molecules to the cell. We purified a 100 kDa protein…”
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Sa1117: A NEWLY DISCOVERED REGULATORY CD8 T CELL NETWORK HAS THE POTENTIAL TO REGULATE AND ELIMINATE PATHOGENIC CD4 T CELLS IN AUTOIMMUNE MEDIATED DIGESTIVE DISEASE by Crane, Courtney, Bowser, Justin, Fasnacht, Rachael, Gardell, Jennifer, Julien, Susan, Maurer, Meghan, Templeton, Megan L., Therriault, Jon, Swiderek, Kristine M.

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A NEWLY DISCOVERED REGULATORY CD8 T CELL NETWORK HAS THE POTENTIAL TO REGULATE AND ELIMINATE PATHOGENIC CD4 T CELLS IN AUTOIMMUNE MEDIATED DISEASE OF THE GUT by Crane, Courtney, Bowser, Justin, Fasnacht, Rachael, Gardell, Jennifer, Maurer, Meghan, Julien, Susan, Templeton, Megan, Therriault, Jon Henry, Swiderek, Kristine

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